1. Articles from David P. Kreil

    1-4 of 4
    1. Polarization-Sensitive Optical Coherence Tomography and Conventional Retinal Imaging Strategies in Assessing Foveal Integrity in Geographic Atrophy

      Polarization-Sensitive Optical Coherence Tomography and Conventional Retinal Imaging Strategies in Assessing Foveal Integrity in Geographic Atrophy

      Purpose : To compare current imaging methods with respect to their ability to detect the condition of the fovea in patients with geographic atrophy (GA). Methods : The retinas of 176 eyes with GA were imaged using two spectral-domain optical coherence tomography (SD-OCT) systems, Cirrus HD-OCT and Spectralis HRA+OCT, and fundus autofluorescence (FAF) and infrared imaging (IR) was used in the scanning laser ophthalmoscope (SLO) mode. Polarization-sensitive OCT (PS-OCT), which selectively visualizes the RPE in addition to SD-OCT features, was used to image 95 eyes. Geographic atrophy lesions were categorized as fovea spared, involved, or not quantifiable (grades 0, 1, and ...

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    2. A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

      A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy

      Purpose To identify reliable criteria based on spectral-domain optical coherence tomography (SD-OCT) to monitor disease progression in geographic atrophy due to age-related macular degeneration (AMD) compared with lesion size determination based on fundus autofluorescence (FAF). Design Prospective longitudinal observational study Methods Setting :Institutional. Study population A total of 48 eyes in 24 patients with geographic atrophy. Observation Procedures Eyes with geographic atrophy were included and examined at baseline and months 3, 6, 9 and 12. At each study visit best-corrected visual acuity (BCVA), FAF and SD-OCT imaging using a Spectralis HRA + OCT System were performed. FAF images were analyzed using ...

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    3. A systematic correlation of morphology and function using spectral domain optical coherence tomography and microperimetry in patients with geographic atrophy

      A systematic correlation of morphology and function using spectral domain optical coherence tomography and microperimetry in patients with geographic atrophy

      Aims This study has been designed to describe the functional impact of distinct pathologies within the retinal layers in patients with geographic atrophy (GA) by means of a point-to-point correlation between optical coherence tomography (OCT) and microperimetry. Methods Retinal morphology and function of 23 patients suffering from GA of the retinal pigment epithelium (RPE) have been investigated using the Spectralis OCT (Heidelberg Engineering) and the MP1 microperimeter (Nidek Technologies). The point-to-point overlay of morphology and function has been done using proprietary software, allowing OCT image grading to define distinct alterations of the neurosensory retina, the RPE and the choroid. By ...

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    4. A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy

      A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy

      PurposeTo evaluate spectral-domain optical coherence tomography (SD-OCT) in providing reliable and reproducible parameters for grading geographic atrophy (GA) compared with fundus autofluorescence (FAF) images acquired by confocal scanning laser ophthalmoscopy (cSLO).DesignProspective observational study.ParticipantsA total of 81 eyes of 42 patients with GA.MethodsPatients with atrophic age-related macular degeneration (AMD) were enrolled on the basis of total GA lesion size ranging from 0.5 to 7 disc areas and best-corrected visual acuity of at least 20/200. A novel combined cSLO-SD-OCT system (Spectralis HRA-OCT, Heidelberg Engineering, Heidelberg, Germany) was used to grade foveal involvement and to manually measure disease ...

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) Medical University of Vienna
    2. (3 articles) Heidelberg Engineering
    3. (1 articles) Nidek
    4. (1 articles) Columbia University
    5. (1 articles) University of Rochester
    6. (1 articles) Stanford University
    7. (1 articles) Johns Hopkins University
    8. (1 articles) National University of Singapore
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    A Systematic Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Patients with Geographic Atrophy A systematic correlation of morphology and function using spectral domain optical coherence tomography and microperimetry in patients with geographic atrophy A Longitudinal Comparison of Spectral-Domain Optical Coherence Tomography and Fundus Autofluorescence in Geographic Atrophy Polarization-Sensitive Optical Coherence Tomography and Conventional Retinal Imaging Strategies in Assessing Foveal Integrity in Geographic Atrophy Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea Optical coherence tomography image based eye disease detection using deep convolutional neural network Optical Coherence Tomography Biomarkers in Predicting Treatment Outcomes of Diabetic Macular Edema After Dexamethasone Implants Macular and Optic Disc Parameters in Children with Amblyopic and Nonamblyopic Eyes under Optical Coherence Tomography Fundus Images Optical coherence tomography assessment of the enamel surface after debonding the ceramic brackets using three different techniques Schizophrenia in Translation: Why the Eye? Advances in OCT Imaging in Myopia and Pathologic Myopia