1. Articles from Michael F. Chiang

    1-6 of 6
    1. 105° field of view non-contact handheld swept-source optical coherence tomography

      105° field of view non-contact handheld swept-source optical coherence tomography

      We demonstrate a handheld swept-source optical coherence tomography (OCT) system with a 400 kHz vertical-cavity surface-emitting laser (VCSEL) light source, a non-contact approach, and an unprecedented single shot 105° field of view (FOV). We also implemented a spiral scanning pattern allowing real-time visualization with improved scanning efficiency. To the best of our knowledge, this is the widest FOV achieved in a portable non-contact OCT retinal imaging system to date. Improvements to the FOV may aid the evaluation of retinal diseases such as retinopathy of prematurity, where important vitreoretinal changes often occur in the peripheral retina.

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    2. Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic

      Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic

      This study was designed to evaluate iVue Spectral-domain optical coherence tomography (SD-OCT) effectiveness in screening for eye disease compared to clinical examination. Subjects were recruited from the Casey Eye Community Outreach Program Mobile Clinic during its routinely scheduled outreach clinics to indigent, underserved populations throughout Oregon. Macular optical coherence tomography interpretation and automated optical coherence tomography analysis were compared to the clinical examination, with specific attention to findings indicative of retinal abnormalities, risks for glaucoma, and narrow angles. As a result, a total of 114 subjects were included in this study. In diabetics, optical coherence tomography and clinical exam were ...

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    3. High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source

      High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source

      Optical coherence tomography (OCT) and OCT angiography (OCTA) enable noninvasive structural and angiographic imaging of the eye. Portable handheld OCT/OCTA systems are required for imaging patients in the supine position. Examples include infants in the neonatal intensive care unit (NICU) and operating room (OR). The speed of image acquisition plays a pivotal role in acquiring high-quality OCT/OCTA images, particularly with the handheld system, since both the operator hand tremor and subject motion can cause significant motion artifacts. In addition, having a large field of view and the ability of real-time data visualization are critical elements in rapid disease ...

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    4. Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity

      Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity

      Importance Retinopathy of prematurity (ROP) is a leading cause of childhood blindness worldwide. Optical coherence tomography (OCT) has improved the care of adults with vitreoretinal disease, and OCT angiography (OCTA) is demonstrating promise as a technique to visualize the retinal vasculature with lower risk and cost than fluorescein angiography. However, to date, there are no commercially available devices able to obtain ultra–wide-field OCT or OCTA images in neonates. Objective To obtain ultra–wide-field OCT and OCTA images in neonates with ROP using a prototype handheld OCT and OCTA device. Design, Setting, and Participants This observational case series was conducted ...

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    5. Outer Retinal Structural Alternation and Segmentation Errors in Optical Coherence Tomography Imaging in Patients with a History of Retinopathy of Prematurity

      Outer Retinal Structural Alternation and Segmentation Errors in Optical Coherence Tomography Imaging in Patients with a History of Retinopathy of Prematurity

      Purpose To evaluate retinal anatomy and segmentation errors from spectral domain optical coherence tomography (SD-OCT) imaging (MM5 protocol of RTVue-100; Optovue, Inc., Fremont, CA) in school-aged children. Design A prospective cohort study in a referral medical center. Methods 133 eyes of 133 patients were enrolled. Patients were grouped as those who were treated for retinopathy of prematurity (ROP) (ROP-Tx-group); those with spontaneously-regressed ROP (ROP-non-Tx-group); other premature patients (premature group); and full-term age-matched children (full-term group). Anatomy and segmentation errors of retina were evaluated by SD-OCT. Results The mean age at assessment was 9.5 years (range 4–16 years). The ...

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      Mentions: Optovue
    6. Applying newer technology to your practice in pediatric ophthalmology and strabismus

      Applying newer technology to your practice in pediatric ophthalmology and strabismus
      Relevance: Imaging modalities like optical coherence tomography enable us to view and document details of ocular anatomy. These tools which are commonly used by our colleagues in cornea, glaucoma and retina, should be incorporated in the pediatric ophthalmology practice. Posterior segment OCT can be used to objectively monitor children with glaucoma, measure RNFL changes in papilledema or optic atrophy, study foveal morphology in diseases like retinoschisis. Anterior segment OCT can be used to assess anterior chamber depth, measure white-to-white distance, document the thickness of both the ciliary body and lens in children with anterior segment abnormalities. Newer technology now allow ...
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    1-6 of 6
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  2. Topics in the News

    1. (4 articles) Oregon Health & Science University
    2. (3 articles) Center for Ophthalmic Optics and Lasers
    3. (2 articles) National Institutes of Health
    4. (2 articles) Simon Fraser University
    5. (1 articles) Optovue
    6. (1 articles) Capital Medical University
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    Applying newer technology to your practice in pediatric ophthalmology and strabismus Outer Retinal Structural Alternation and Segmentation Errors in Optical Coherence Tomography Imaging in Patients with a History of Retinopathy of Prematurity Handheld OCT Angiography and Ultra–Wide-Field OCT in Retinopathy of Prematurity High-speed and widefield handheld swept-source OCT angiography with a VCSEL light source Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic 105° field of view non-contact handheld swept-source optical coherence tomography Trojan-Horse Diameter-Reducible Nanotheranostics for Macroscopic/Microscopic Imaging-Monitored Chemo-Antiangiogenic Therapy Thickness of retinal pigment epithelium–Bruch’s membrane complex in adult Chinese using optical coherence tomography Interocular symmetry of optical coherence tomography parameters in healthy children and adolescents Fluorescein Leakage and Optical Coherence Tomography Angiography Features of Microaneurysms in Diabetic Retinopathy Cross-free in both lateral and axial directions Fourier-domain full-field optical coherence tomography Microperimetry, Humphrey field analyzer, and optical coherence tomography in detecting glaucoma: a comparative performance study