1. Articles from Y. Yasuno

    1-8 of 8
    1. Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography

      Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography

      We evaluated intraretinal RPE migration in AMD using multimodal imaging including polarimetric images. Depolarized light images were computed using a PS-SLO. M-DOPU was calculated using multifunctional Jones-matrix OCT. RPE migration was detected in 59 of 155 eyes. Focal similarities could be confirmed among en-face projection images of minimum M-DOPU, depolarized light images, and NIR-AF images.

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    2. Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography

      Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography

      Quantitative evaluation of optical properties of choroid and sclera are performed by multifunctional optical coherence tomography. Five normal eyes, five glaucoma eyes and one choroidal atrophy eye are examined. The refractive error was found to be correlated with choroidal birefringence, polarization uniformity, and flow in addition to scleral birefringence among normal eyes. The significant differences were observed between the normal and the glaucoma eyes, as for choroidal polarization uniformity, flow and scleral birefringence. An automatic segmentation algorithm of retinal pigment epithelium and chorioscleral interface based on multifunctional signals is also presented.

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    3. Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography

      Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography

      Collagen crosslinking (CXL) has shown promising results in the prevention of the progression of keratoconus and corneal ectasia. However, techniques for in vivo and in situ assessment of the treatment are limited. In this study, ex vivo porcine eyes were treated with a chemical CXL agent (glutaraldehyde), during which polarization sensitive optical coherence tomography (PS-OCT) recordings were acquired simultaneously to assess the sensitivity of the technique to assess changes in the cornea. The results obtained in this study suggest that PSOCT may be a suitable technique to measure CXL changes in situ and to assess the local changes in the ...

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    4. Visualization of Sub-Retinal Pigment Epithelium and Sub-Choroidal Neovascularization Morphologies of Exudative Macular Diseases by Optical Coherence Tomography with Long Wavelength Probe.

      Visualization of Sub-Retinal Pigment Epithelium and Sub-Choroidal Neovascularization Morphologies of Exudative Macular Diseases by Optical Coherence Tomography with Long Wavelength Probe. Invest Ophthalmol Vis Sci. 2008 Aug 1; Authors: Yasuno Y, Miura M, Kawana K, Makita S, Sato M, Okamoto F, Yamanari M, Iwasaki T, Yatagai T, Oshika T Purpose: To evaluate the clinical significance of the newly developed long wavelength probe optical coherence tomography (LP-OCT) for the diagnosis of exudative macular diseases. Participants: Fourteen eyes of 13 cases were prospectively involved in this study. The cases included 7 type-I and 5 type-II choroidal neovascularization (CNV) cases associated with age ...
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    5. Three-dimensional optical coherence tomography of proliferative diabetic retinopathy.

      Fourier-domain optical coherence tomography (OCT) was used to image the three-dimensional (3D) structures of the proliferative membrane in proliferative diabetic retinopathy. The case of a 51-year-old man with retinal detachment of the macula in his left eye is reported. The proliferative membrane covered the entire macular area. In the OCT image, the 3D structure of the proliferative membrane could be clearly visualised. The OCT image showed the presence of multiple adhesions between the retina and the proliferative membrane and separation of the proliferative membrane. The patient underwent three-port vitrectomy, and the extent and locations of the adhesions corresponded well with ...
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    6. Three-dimensional Anterior Segment Optical Coherence Tomography of Filtering Blebs After Trabeculectomy.

      PURPOSE: To evaluate trabeculectomy blebs by using 3-dimensional anterior segment optical coherence tomography (OCT). METHODS: We prospectively examined 4 eyes of 4 patients who developed filtering blebs after trabeculectomy. A 1310-nm high-speed OCT prototype was used to image the 3-dimensional structure of the filtering blebs. RESULTS: The 3-dimensional structure of the filtering blebs was clearly observed in the OCT images. Three types of filtering blebs were observed: diffuse blebs in 2 eyes, an encapsulated bleb in 1 eye, and a nonfunctioning cystic bleb in 1 eye. The volume of each bleb was 9.97, 1.10, 0.76, and 0 ...
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    7. Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry.

      Phase retardation measurement of retinal nerve fiber layer by polarization-sensitive spectral-domain optical coherence tomography and scanning laser polarimetry. J Biomed Opt. 2008 Jan-Feb;13(1):014013 Authors: Yamanari M, Miura M, Makita S, Yatagai T, Yasuno Y Phase retardation of in vivo human retinal nerve fiber layer (RNFL) is quantitatively measured by two methods-polarization-sensitive spectral-domain optical coherence tomography (PS-SD-OCT) and scanning laser polarimetry (SLP). An en face cumulative phase retardation map is calculated from the three-dimensional (3-D) phase retardation volume of healthy and glaucomatous eyes measured by PS-SD-OCT. It is shown that the phase retardation curves around the optic nerve ...
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    8. In vivo Three-Dimensional Birefringence Analysis Shows Collagen Differences between Young and Old Photo-Aged Human Skin.

      Polarization-sensitive optical coherence tomography (PS-OCT) permits non-invasive visualization of dermal birefringence, mainly due to collagenous structures. The purpose of this study is to use PS-OCT to assess intrinsic-age-related and photo-age-related differences in three-dimensional dermal birefringence. We measured dermal birefringence of the cheek skin and photo-protected interior upper arm skin from old and young volunteers. The algorithm that we used automatically produces the transversal dermal birefringence map from the polarization-sensitive OCT volume. This allowed quantitative comparison and visualization of the transverse distribution of the dermal birefringence. We found that dermal birefringence of the cheek skin was significantly smaller in the old ...

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      Mentions: Akiko Matsumoto
    1-8 of 8
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  2. Topics in the News

    1. (5 articles) Tokyo Medical University
    2. (5 articles) Shuichi Makita
    3. (5 articles) Yoshiaki Yasuno
    4. (4 articles) University of Tsukuba
    5. (4 articles) Masahiro Miura
    6. (3 articles) Masahiro Yamanari
    7. (2 articles) Tomey Corporation
    8. (1 articles) Indiana University
    9. (1 articles) Akiko Matsumoto
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    Non-invasive assessment of corneal crosslinking changes using polarization sensitive optical coherence tomography Quantitative polarization and flow evaluation of choroid and sclera by multifunctional Jones matrix optical coherence tomography Evaluation of intraretinal migration of retinal pigment epithelial cells with Jones matrix optical coherence tomography Structure–Function Correlation Using OCT Angiography And Microperimetry In Diabetic Retinopathy Response to Re: Evaluation of choroidal changes in adolescent idiopathic scoliosis using enhanced depth imaging optical coherence tomography OCT Image-Guided Treatment of Scars (Book Chapter) Spatial coordinate corrected motion tracking for optical coherence elastography Signal-to-background ratio and lateral resolution in deep tissue imaging by optical coherence microscopy in the 1700 nm spectral band Evaluation of the choroidal features in pachychoroid spectrum diseases by optical coherence tomography and optical coherence tomography angiography Improved description of the signal formation in grating generated-optical coherence tomography Optical Coherence Tomography for Imaging Dental Caries (Book Chapter) Topography and pachymetry maps for mouse corneas using optical coherence tomography