1. Articles from Nienke S. van Ditzhuijzen

    1-8 of 8
    1. EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging

      EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging

      Aims: Qualitative criteria for plaque tissue characterisation by OCT are well established, but quantitative methods lack systematic validation in vivo . High optical attenuation coefficient µ t has been associated with unstable plaque features, such as lipid core. The purpose of this study was to validate optical coherence tomography (OCT) attenuation imaging for tissue characterisation in vivo , specifically to detect lipid core in coronary atherosclerotic plaques, and to evaluate quantitatively the ability of OCT attenuation imaging to differentiate thin-cap (TCFA) and thick-cap fibroatheroma (FA). Methods and results: We prospectively enrolled 85 patients undergoing imaging of a native coronary segment by both OCT ...

      Read Full Article
    2. Three-dimensional registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      Three-dimensional registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      Evidence suggests high-resolution, high-contrast, 100    frames / s 100  frames/s intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and three-dimensional (3-D) registration methods to provide validation of IVOCT pullback volumes using microscopic, color, and fluorescent cryo-image volumes with optional registered cryo-histology. A specialized registration method matched IVOCT pullback images acquired in the catheter reference frame to a true 3-D cryo-image volume. Briefly, an 11-parameter registration model including a polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition ...

      Read Full Article
    3. 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation

      High resolution, 100 frames/sec intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and 3D registration methods, to provide validation of IVOCT pullback volumes using microscopic, brightfield and fluorescent cryoimage volumes, with optional, exactly registered cryo-histology. The innovation was a method to match an IVOCT pullback images, acquired in the catheter reference frame, to a true 3D cryo-image volume. Briefly, an 11-parameter, polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition. Virtual catheter parameters were optimized to ...

      Read Full Article
    4. Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound

      Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound

      Aims Previous studies have reported the safety and feasibility of both time-domain optical coherence tomography (TD-OCT) and Fourier-domain OCT (FD-OCT) in highly selected patients and clinical settings. However, the generalizability of these data is limited, and data in unselected patient populations reflecting a routine cathlab practice are lacking. We compared safety of intracoronary FD-OCT imaging to intravascular ultrasound (IVUS) imaging in a large real-world series of consecutive patients who underwent invasive imaging during coronary catheterization in our centre. Methods and results This is a prospective, single-centre registry of patients scheduled for coronary angiography or intervention undergoing intracoronary imaging with FD-OCT ...

      Read Full Article
    5. OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold

      OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold

      Background Although recent observations suggest a favorable initial healing process of the everolimus-eluting bioresorbable vascular scaffold (BVS), little is known regarding long-term healing response. Objectives This study assessed the in vivo vascular healing response using optical coherence tomography (OCT) 5 years after elective first-in-man BVS implantation. Methods Of the 14 living patients enrolled in the Thoraxcenter Rotterdam cohort of the ABSORB A study, 8 patients underwent invasive follow-up, including OCT, 5 years after implantation. Advanced OCT image analysis included luminal morphometry, assessment of the adluminal signal-rich layer separating the lumen from other plaque components, visual and quantitative tissue characterization, and ...

      Read Full Article
    6. A novel method to assess coronary artery bifurcations by OCT: cut-plane analysis for side-branch ostial assessment from a main-vessel pullback

      A novel method to assess coronary artery bifurcations by OCT: cut-plane analysis for side-branch ostial assessment from a main-vessel pullback

      Aims In coronary bifurcations assessment, evaluation of side-branch (SB) ostia by an optical coherence tomography (OCT) pullback performed in the main branch (MB) could speed up lesion evaluation and minimize contrast volume. Dedicated software that reconstructs the cross-sections perpendicular to the SB centreline could improve this assessment. We aimed to validate a new method for assessing the SB ostium from an OCT pullback performed in the MB. Methods and results Thirty-one sets of frequency-domain OCT pullbacks from 28 patients, both from the MB and the SB of a coronary artery bifurcation were analysed. Measurements of the SB ostium from the ...

      Read Full Article
    7. Optical Coherence Tomography-guided Bifurcation Stenting of a Coronary Artery Dissection

      Optical Coherence Tomography-guided Bifurcation Stenting of a Coronary Artery Dissection

      Periprocedural guide-wire induced coronary artery dissection is a rare but potentially serious complication of PCI. Immediate stenting of the entry point is one of the therapeutic options but engaging the guide-wire in the true lumen may be challenging. We report a case of a 55-year-old woman with a guide-wire induced coronary dissection that occurred during treatment of a bifurcation lesion. Optical coherence tomography was instrumental to distinguish true form false lumen and thereby guide correct positioning of the guide-wire to successfully treat the lesion using a dedicated bifurcation stent.

      Read Full Article
    8. Plaque and thrombus evaluation by optical coherence tomography

      Plaque and thrombus evaluation by optical coherence tomography
      Intravascular Optical Coherence Tomography has been explored as an imaging tool for vessel wall and thrombus characterization. OCT enables a high resolution arterial wall imaging, and light properties allow tissue characterization. It has been proved one of the most valuable imaging modalities for the evaluation of vulnerable plaque and thrombus. OCT has a unique capacity in volumetric quantification of calcium, and unlike ultrasound, light can easily penetrate calcified plaques. Finally, this review paper will address aspects of the validation method of plaque characterization and potential pitfalls and put in perspective new approaches that may help the evolution of the field.
      Read Full Article
    1-8 of 8
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (5 articles) Erasmus University
    2. (5 articles) Evelyn Regar
    3. (4 articles) Antonios Karanasos
    4. (4 articles) Jurgen M. Ligthart
    5. (4 articles) Robert-Jan van Geuns
    6. (3 articles) Case Western Reserve University
    7. (3 articles) Gijs van Soest
    8. (3 articles) Hiram G. Bezerra
    9. (3 articles) Shengxian Tu
    10. (3 articles) Karen T. Witberg
  3. Popular Articles

  4. Picture Gallery

    Plaque and thrombus evaluation by optical coherence tomography Optical Coherence Tomography-guided Bifurcation Stenting of a Coronary Artery Dissection A novel method to assess coronary artery bifurcations by OCT: cut-plane analysis for side-branch ostial assessment from a main-vessel pullback OCT Assessment of the Long-Term Vascular Healing Response 5 Years After Everolimus-Eluting Bioresorbable Vascular Scaffold Safety of optical coherence tomography in daily practice: a comparison with intravascular ultrasound 3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation Three-dimensional registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation EuroIntervention Automated characterisation of lipid core plaques in vivo by quantitative optical coherence tomography tissue type imaging Retinal Vascular Features in Ocular Blunt Trauma by Optical Coherence Tomography Angiography Non-invasive imaging of a choroidal macrovessel Correlation between optical coherence tomography, multifocal electroretinogram findings and visual acuity in diabetic macular edema Digital Wavefront Sensing