1. Articles from Nicolas Foin

    1-14 of 14

    1. Intracoronary imaging using attenuation-compensated optical coherence tomography allows better visualisation of coronary artery diseases

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      Intracoronary imaging using attenuation-compensated optical coherence tomography allows better visualisation of coronary artery diseases

      Purpose To allow an accurate diagnosis of coronary artery diseases by enhancing optical coherence tomography (OCT) images of atheromatous plaques using a novel automated attenuation compensation technique. Background One of the major drawbacks of coronary OCT imaging is the rapid attenuation of the OCT signal, limiting penetration in tissue to only few millimetres. Visualisation of deeper anatomy is however critical for accurate assessment of plaque burden in-vivo. Methods A compensation algorithm, previously developed to correct for light attenuation in soft tissues and to enhance contrast in ophthalmic OCT images, was applied to intracoronary plaque imaging using spectral-domain OCT. Results Application ...

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      Mentions: Imperial College London University College London Carlo Di Mario

    2. Optical coherence tomography to guide the treatment of chronic total occlusions (Book Chapter)

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      Optical coherence tomography to guide the treatment of chronic total occlusions (Book Chapter)

      Intra-coronary imaging can enhance the success rate of CTO recanalization, improving the mid- to long-term outcome, and decreasing the incidence of sub-optimal stent deployment. Percutaneous coronary interventions (PCI) to chronic total occlusions (CTO) of the coronary arteries are amongst the most challenging lesions faced by the interventional cardiologist. This chapter aims to describe the role of a recently introduced technology optical coherence tomography (OCT) in the treatment of CTO, outlining the principles underlying the use of OCT, summarizing research on the use of this technique to date, and proposing possible future applications in percutaneous coronary interventions. Intravascular ultrasound (IVUS) continues ...

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      Mentions: Carlo Di Mario Royal Brompton Hospital Ron Waksman

    4. Immediate results of bifurcational stenting assessed with optical coherence tomography

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      Immediate results of bifurcational stenting assessed with optical coherence tomography

      Background: A tubular stent may adapt with difficulty to coronary bifurcation lesions (CBLs). Methods: Time domain or frequency domain (FD) optical coherence tomography (OCT) was performed to assess strut apposition immediately after stent implantation across four segments inside the bifurcation, in a consecutive series of patients. OCT pullbacks were performed in the main vessel (MV). Results: A total of 13,142 struts in 45 CBL in 41 patients were assessed. Strut malapposition was significantly more frequent in the half bifurcation facing the side-branch (SB) ostium (42.9%) than in the proximal segment of the bifurcation 11.8%, half bifurcation opposite ...

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    5. Healing of floating unapposed drug eluting stent struts: insights from 3D optical coherence tomography

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      Healing of floating unapposed drug eluting stent struts: insights from 3D optical coherence tomography

      Pathological evidence suggests that coverage of malapposed struts in Drug Eluting Stents is necessary to limit risks of late and very late stent thrombosis. In this case report, the coverage of the struts left unapposed in bifurcations using 3D Optical Coherence Tomography is illustrated. The follow-up with optical coherence tomography (OCT) suggests that struts which were left unapposed at the ostium become covered with a thick layer of tissue, which differs from the thin coverage found on well-apposed struts. Questions are raised as to whether such coverage is able to functionally isolate the metallic struts left unapposed and eliminate the ...

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      Mentions: Imperial College London Lightlab C7 XR OCT Imaging System St. Jude Medical

    6. Feature Of The Week 9/9/12: Imaging of Coronary Artery Plaques Using Contrast Enhanced Optical Coherence Tomography

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      Feature Of The Week 9/9/12: Imaging of Coronary Artery Plaques Using Contrast Enhanced Optical Coherence Tomography

      Optical Coherence Tomography (OCT) has recently emerged as a promising technology for intravascular guidance of interventions. With a resolution on the order of 10 microns, Intravascular OCT surpasses Intravascular Ultrasounds, and allows for precise measurement of cap thickness and identification of lipid rich Thin-Cap Fibroatheroma (TCFA). The diagnostic accuracy and assessment of atherosclerotic plaque morphology with OCT remains however limited by the rapid attenuation of OCT signal in tissue, limiting contrast on deep plaque structure and accurate assessment of plaque burden.A contrast enhancement algorithm, previously developed to compensate for light attenuation in spectral-domain OCT images of the human optic ...

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    7. Imaging of coronary artery plaques using contrast-enhanced optical coherence tomography

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Imaging of coronary artery plaques using contrast-enhanced optical coherence tomography

      Optical coherence tomography (OCT) has recently emerged as a promising technology for intravascular guidance of interventions. With a resolution on the order of 10µm, intravascular OCT surpasses intravascular ultrasounds, and allows for precise measurement of cap thickness and identification of lipid-rich thin-cap fibroatheroma. The diagnostic accuracy and assessment of atherosclerotic plaque

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    9. Optical coherence tomography: from research to practice

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Optical coherence tomography: from research to practice

      Optical coherence tomography (OCT) is a high-resolution imaging technique with great versatility of applications. In cardiology, OCT has remained hitherto as a research tool for characterization of vulnerable plaques and evaluation of neointimal healing after stenting. However, OCT is now successfully applied in different clinical scenarios, and the introduction of frequency domain analysis simplified its application to the point it can be considered a potential alternative to intravascular ultrasound for clinical decision-making in some cases. This article reviews the use of OCT for assessment of lesion severity, characterization of acute coronary syndromes, guidance of intracoronary stenting, and evaluation of long-term ...

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    10. Choosing the right cell: guidance with three-dimensional optical coherence tomography of bifurcational stenting

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Choosing the right cell: guidance with three-dimensional optical coherence tomography of bifurcational stenting

      A 36-year-old male with progressive exertional angina, inducible anterolateral ischaemia, and single-vessel disease involving the bifurcation left anterior descending coronary artery (LAD)/first diagonal branch (Panel 1A). Panel 1B shows the three-dimensional (3D)-optical coherence tomography (OCT) image of a 2.75 × 28 mm Integrity RESOLUTE® stent with a wire crossing the...

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    11. Frequency domain optical coherence tomography for guidance of coronary stenting

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      Frequency domain optical coherence tomography for guidance of coronary stenting
      Objective To evaluate the role of Frequency domain optical coherence tomography (FD-OCT) in guiding stent implantation procedures. Methods Dragonfly™-imaging catheter was used pre-intervention, after pre-dilatation or at various stages of stent deployment/post-dilatation to assess lesion severity, characteristics and guide stent expansion/apposition. Results We performed 398 OCT pull-backs in 108 consecutive patients. The 371 pull-backs analysable, had an average length of 35 mm and encompassed 193 lesions (1.8 lesions per patient). Seventy-six percent of patient had AHA-ACC-class B–C lesions. In the pre-intervention group deferral of treatment was decided for 13/68 pullbacks (19.1%), whereas strategies ...
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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    12. Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons

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      Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons

      Aims: The treatment of in-stent restenosis (ISR) remains a challenge with poor immediate results and higher restenosis rate than in de novo lesions. We propose, based on a consecutive series of patients treated with cutting balloon, a strategy of aggressive device selection based on the results of serial FD-OCT assessment.

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      Mentions: Imperial College London Carlo Di Mario Royal Brompton Hospital

    13. Jailed side branches: fate of unapposed struts studied with 3D frequency-domain optical coherence tomography

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      Jailed side branches: fate of unapposed struts studied with 3D frequency-domain optical coherence tomography

      We report the case of a 64-year-old man treated for stable angina with two bare-metal stents in the proximal-mid segment of the left anterior descending artery at the bifurcation with the first diagonal and second septal branches without final kissing balloon dilatation. Seven months later he complained of recurrent angina. Frequency-domain optical coherence tomography (OCT) with three-dimensional (3D) reconstruction was performed, showing a thick rim of neointimal proliferation at the ostium of both branches, causing severe restenosis. Deployment of a stent in a bifurcation main branch without opening the struts at the side-branch ostium may facilitate focal restenosis.

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      Mentions: Carlo Di Mario Royal Brompton Hospital Nicolas Foin

    14. Optical coherence tomography for guidance in bifurcation lesion treatment

      Explore eurointervention.org Cardiology
      Optical coherence tomography for guidance in bifurcation lesion treatment

      Images acquired of coronary vessels during a pullback of time-domain optical coherence tomography (OCT) are influenced y the dynamics of the heart. T his study explores the feasibility of applying an in-house developed retrospective imaging-based gating method for OCT and the influence of catheter dislocation and luminal changes during the cardiac cycle on the outcome of quantitative OCT (QOCT).

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      Mentions: Carlo Di Mario Royal Brompton Hospital Erasmus Medical Center
    1-14 of 14
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    1. (14 articles) Nicolas Foin
    2. (12 articles) Royal Brompton Hospital
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    6. (6 articles) Lightlab C7 XR OCT Imaging System
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    Optical coherence tomography for guidance in bifurcation lesion treatment Jailed side branches: fate of unapposed struts studied with 3D frequency-domain optical coherence tomography Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons Frequency domain optical coherence tomography for guidance of coronary stenting Choosing the right cell: guidance with three-dimensional optical coherence tomography of bifurcational stenting Optical coherence tomography: from research to practice Optical coherence tomography for guidance of distal cell recrossing in bifurcation stenting: choosing the right cell matters Imaging of coronary artery plaques using contrast-enhanced optical coherence tomography Feature Of The Week 9/9/12: Imaging of Coronary Artery Plaques Using Contrast Enhanced Optical Coherence Tomography Longitudinal Stent Compression Demonstrated by Angiographic “Wedding Band” and 3-Dimensional Optical Coherence Tomography