1. Articles from R. W. Kirk

    1-2 of 2
    1. 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      Evaluation of degradation in the structure of skeletal muscle is important for the assessment or diagnosis of many myopathies, such as Duchenne muscular dystrophy. Histological analysis is the gold standard to evaluate such degradation but requires excision and fixation of the tissue. This is undesirably invasive in patients and precludes longitudinal study of disease progression in patients or animal models. Optical coherence tomography (OCT) is a high-resolution (∼10μm) imaging modality capable of visualising muscle structure and the morphological changes in muscular dystrophy. However, because of the limited image penetration of OCT (∼2mm), previous studies have been restricted to imaging ...

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    2. Ultrathin side-viewing needle probe for optical coherence tomography

      Ultrathin side-viewing needle probe for optical coherence tomography

      We present the smallest reported side-viewing needle probe for optical coherence tomography (OCT). Design, fabrication, optical characterization, and initial application of a 30-gauge (outer diameter 0.31 mm) needle probe are demonstrated. Extreme miniaturization is achieved by using a simple all-fiber probe design incorporating an angle-polished and reflection-coated fiber-tip beam deflector. When inserted into biological tissue, aqueous interstitial fluids reduce the probe’s inherent astigmatism ratio to 1.8, resulting in a working distance of 300 μm and a depth-of-field of 550 μm with beam diameters below 30 μm. The needle probe was interfaced with an 840 nm spectral-domain OCT ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) University of Western Australia
    2. (2 articles) Dirk Lorenser
    3. (2 articles) Xiaojie Yang
    4. (2 articles) David D. Sampson
    5. (2 articles) Rodney W. Kirk
    6. (1 articles) Robert A. McLaughlin
    7. (1 articles) Center for Ophthalmic Optics and Lasers
    8. (1 articles) Yale University
    9. (1 articles) University of Copenhagen
    10. (1 articles) Oregon Health & Science University
    11. (1 articles) Michael Larsen
    12. (1 articles) David Huang
    13. (1 articles) Michael A. Choma
    14. (1 articles) Steven T. Bailey
    15. (1 articles) Christina J. Flaxel
    16. (1 articles) Yali Jia
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    Ultrathin side-viewing needle probe for optical coherence tomography 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe Dispersion and compensation of optical coherence tomography using double-path rapid scanning optical delay line Evaluation of the macular choroidal thickness using spectral-domain optical coherence tomography in patients with obstructive sleep apnoea syndrome: response Application of fractional flow reserve and optical coherence tomography examinations in a patient presenting with recurrent angina: a case report OPTICAL COHERENCE TOMOGRAPHY IN JUVENILE NEURONAL CEROID LIPOFUSCINOSIS OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY FEATURES OF DIABETIC RETINOPATHY Long-Term Changes of Macular Thickness after Pars Plana Vitrectomy in Optic Disc Pit Maculopathy: A Spectral-Domain Optical Coherence Tomography Study Quantifying hyperoxia-mediated damage to mammalian respiratory cilia-driven fluid flow using particle tracking velocimetry optical coherence tomography Two-grating Talbot bands spectral-domain interferometer Natural History of Idiopathic Epiretinal Membrane in Eyes with Good Vision Assessed by Spectral-Domain Optical Coherence Tomography Optical coherence tomography angiography of shallow irregular pigment epithelial detachments in pachychoroid spectrum disease - American Journal of Ophthalmology