1. Articles from Eric Thorin

    1-2 of 2

    1. Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

      Explore AJP - Heart and Circulatory Physiology
      Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

      Endothelial dysfunction and oxidative stress contribute to the atherosclerotic process that includes stiffening of large peripheral arteries. In contrast, we previously reported a paradoxical increase in cerebrovascular compliance in LDLr-/-: hApoB+/+ atherosclerotic (ATX) mice. We hypothesized that prevention of cerebral artery endothelial function with a chronic dietary antioxidant intake would normalize the changes in cerebral artery wall structure and biomechanics and prevent the decline in basal cerebral blood flow (CBF) associated with atherosclerosis. Three-month old ATX mice were treated, or not, for 3 months with the polyphenol (+)-catechin (CAT, 30 mg/kg/day) and compared to wild-type (WT) controls. In ...

      Read Full Article
      Mentions: University of Montreal Polytechnique Montreal Frédéric Lesage

    2. Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

      Explore AJP - Heart and Circulatory Physiology Cardiology
      Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

      Severe dyslipidemia and the associated oxidative stress, could accelerate the age-related decline in cerebrovascular endothelial function and cerebral blood flow (CBF), leading to neuronal loss and impaired learning abilities. We hypothesized that a chronic treatment with the polyphenol catechin would prevent endothelial dysfunction, maintain CBF responses and protect learning abilities in atherosclerotic (ATX) mice. We treated ATX (C57Bl/6-LDLR-/-hApoB+/+; 3 month-old, m/o) mice with catechin (30 mg/kg/day) for 3 months, and C57Bl/6 (WT, 3 and 6-m/o) mice were used as controls. ACh- and flow-mediated dilations (FMD) were recorded in pressurized cerebral arteries. Basal CBF ...

      Read Full Article
      Mentions: Polytechnique Montreal Frédéric Lesage
    1-2 of 2
  1. Search:

  2. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology

    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents

    3. Technology:

      Broadband Sources, Probes, Tunable Sources

    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks

  4. Topics in the News

    1. (2 articles) Polytechnique Montreal
    2. (2 articles) Frédéric Lesage
    3. (2 articles) Nanjing University of Science and Technology
    4. (1 articles) University of Montreal
    5. (1 articles) Singapore Eye Research Institute
    6. (1 articles) Nanyang Technological University

  5. Popular Articles

  6. Picture Gallery

    Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow CT texture analysis of vulnerable plaques on optical coherence tomography Peri-stent contrast staining after ultrathin, biodegradable polymer sirolimus-eluting stent implantation: findings from optical coherence tomography and coronary angioscopy An optimized segmentation and quantification approach in microvascular imaging for OCTA-based neovascular regression monitoring Postdoctoral Research Fellowship at Nanyang Technological University, Singapore The Macular Choriocapillaris Flow in Glaucoma and Within-Day Fluctuations: An Optical Coherence Tomography Angiography Study Impact of Optical Coherence Tomography Imaging on Decision-Making During Percutaneous Coronary Intervention in Patients Presented With Acute Coronary Syndromes Time course of collateral vessel formation after retinal vein occlusion visualized by OCTA and elucidation of factors in their formation Peripapillary Retinal Nerve Fiber Layer and Ganglion Cell-Inner Plexiform Layer Changes on Optical Coherence Tomography in Patients with Unilateral Hypertensive Cytomegalovirus Anterior Uveitis Utility of spectral domain OCT in differentiating optic disc drusen from papilledema in children Plexus-specific retinal vascular anatomy and pathologies as seen by projection-resolved optical coherence tomographic angiography