1. Articles from Edward Baraghis

    1-2 of 2
    1. Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

      Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow

      Endothelial dysfunction and oxidative stress contribute to the atherosclerotic process that includes stiffening of large peripheral arteries. In contrast, we previously reported a paradoxical increase in cerebrovascular compliance in LDLr-/-: hApoB+/+ atherosclerotic (ATX) mice. We hypothesized that prevention of cerebral artery endothelial function with a chronic dietary antioxidant intake would normalize the changes in cerebral artery wall structure and biomechanics and prevent the decline in basal cerebral blood flow (CBF) associated with atherosclerosis. Three-month old ATX mice were treated, or not, for 3 months with the polyphenol (+)-catechin (CAT, 30 mg/kg/day) and compared to wild-type (WT) controls. In ...

      Read Full Article
    2. Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

      Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice

      Severe dyslipidemia and the associated oxidative stress, could accelerate the age-related decline in cerebrovascular endothelial function and cerebral blood flow (CBF), leading to neuronal loss and impaired learning abilities. We hypothesized that a chronic treatment with the polyphenol catechin would prevent endothelial dysfunction, maintain CBF responses and protect learning abilities in atherosclerotic (ATX) mice. We treated ATX (C57Bl/6-LDLR-/-hApoB+/+; 3 month-old, m/o) mice with catechin (30 mg/kg/day) for 3 months, and C57Bl/6 (WT, 3 and 6-m/o) mice were used as controls. ACh- and flow-mediated dilations (FMD) were recorded in pressurized cerebral arteries. Basal CBF ...

      Read Full Article
    1-2 of 2
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (2 articles) Polytechnique Montreal
    2. (2 articles) Frédéric Lesage
    3. (1 articles) University of Montreal
  3. Popular Articles

  4. Picture Gallery

    Catechin treatment improves cerebrovascular flow-mediated dilation and learning abilities in atherosclerotic mice Catechin prevents severe dyslipidemia-associated changes in wall biomechanics of cerebral arteries in LDLr-/-:hApoB+/+ mice and improves cerebral blood flow Extending the depth of focus of fiber-optic optical coherence tomography using a chromatic dual-focus design Ocular toxicity due to colours used during Holi celebration in India: Correlation of clinical findings with the anterior segment OCT Optic coherence tomography appearances of retinal astrocytic hamartoma and systemic features in tuberous sclerosis of Japanese patients MACULAR GANGLION CELL LAYER THICKNESS MEASUREMENT BY SD-OCT IN NON GLAUCOMATOUS MYOPIC EYE AND ITS CORRELATION WITH SPHERICAL EQUIVALENT AND AXIAL LENGTH Optical coherence tomography angiography in myopic choroidal neovascularization after intravitreal ranibizumab Visible-light optical coherence tomography oximetry based on circumpapillary scan and graph-search segmentation Long scan depth optical coherence tomography on imaging accommodation: impact of enhanced axial resolution, signal-to-noise ratio and speed Optical Coherence Tomography of Small Retinoblastoma Interferometric detection of 3D motion using computational subapertures in optical coherence tomography Effect of a coating material containing surface reaction-type pre-reacted glass-ionomer filler on prevention of primary enamel demineralization detected by optical coherence tomography