1. Articles from Hsin-Ming Chen

    1-4 of 4
    1. Method for analyzing mucosa samples with optical coherence tomography

      Method for analyzing mucosa samples with optical coherence tomography

      A method for analyzing mucosa structure with optical coherence tomography (OCT) is provided, and includes: (a) scanning a mucosa sample with optical coherence tomography; (b) choosing a lateral range from a two- or three-dimensional OCT image and analyzing all the A-scan intensity profiles in the lateral range; (c) calculating three indicators in each A-scan intensity profile, including the standard deviation for a certain depth range below the sample surface, the exponential decay constant of the spatial-frequency spectrum and the epithelium thickness under the condition that the basement membrane is identifiable; and (d) using the three indicators of each A-scan intensity ...

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    2. Diagnosis of oral submucous fibrosis with optical coherence tomography

      The epithelium (EP) thickness and the standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer are used as effective indicators for the diagnosis of oral submucous fibrosis (OSF) based on the noninvasive clinical scanning of a swept-source optical coherence tomography (OCT) system of ~6 µm in axial resolution (in tissue) and 103 dB in sensitivity. Compared with the corresponding parameters in healthy oral mucosal mucosa, in OSF mucosa, the EP thickness becomes smaller and the SD of A-mode scan intensity in the LP layer (LP SD) also becomes smaller. The LP SD can also be used ...

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    3. Differentiating oral lesions in different carcinogenesis stages with optical coherence tomography

      A swept-source optical coherence tomography (SS-OCT) system is used to clinically scan oral lesions in different oral carcinogenesis stages, including normal oral mucosa control, mild dysplasia (MiD), moderate dysplasia (MoD), early-stage squamous cell carcinoma (ES-SCC), and well-developed SCC (WD-SCC), for diagnosis purpose. On the basis of the analyses of the SS-OCT images, the stages of dysplasia (MiD and MoD), and SCC (ES-SCC and WD-SCC) can be differentiated from normal control by evaluating the depth-dependent standard deviation (SD) values of lateral variations. In the dysplasia stage, the boundary between the epithelium (EP) and lamina propria (LP) layers can still be identified ...

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    4. Effective indicators for diagnosis of oral cancer using optical coherence tomography

      Effective indicators for diagnosis of oral cancer using optical coherence tomography

      C. C. Yang, Meng-Tsan Tsai, Hsiang-Chieh Lee, Cheng-Kuang Lee, Chuan-Hang Yu, Hsin-Ming Chen, Chun-Pin Chiang, Cheng-Chang Chang, Yih-Ming Wang, C. C. Yang A swept-source optical coherence tomography system is used to clinically scan oral precancer and cancer patients for statistically analyzing the effective indicators of diagnosis. Three indicators are considered, including the standard deviation (SD) of an A-mode scan signal profile, the ... [Opt. Express 16, 15847-15862 (2008)]

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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) National Taiwan University
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    Effective indicators for diagnosis of oral cancer using optical coherence tomography Method for analyzing mucosa samples with optical coherence tomography Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries The role of optical coherence tomography angiography in moderate and advanced primary open-angle glaucoma OCT-angiography follow-up of choroidal neovascularization treated with treat- and- extend aflibercept regimen to avoid over-treatment A Review of Spectroscopic and Non-Spectroscopic Techniques for Diagnosing Breast Cancer Collaboration Between Seno Medical and Cogmedix Drives GOLDEN Results for Innovative Medical Breast Imaging System Prediction of Retinal Ganglion Cell Counts Considering Various Displacement Methods From OCT-Derived Ganglion Cell-Inner Plexiform Layer Thickness Changes of blood flow in macular zone of patients with diabetic retinopathy at different stages evaluated by optical coherence tomography angiography Very late stent thrombosis lacking findings of the typical causes on optical coherence tomography in a patient with SARS-CoV-2 Coarsening of choriocapillaris on optical coherence tomography angiography as a sign of acute idiopathic blind spot enlargement Valve-Like Outflow System Behavior With Motion Slowing in Glaucoma Eyes: Findings Using a Minimally Invasive Glaucoma Surgery-MIGS-Like Platform and Optical Coherence Tomography Imaging