1. Articles from Hsin-Ming Chen

    1-4 of 4

    1. Method for analyzing mucosa samples with optical coherence tomography

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      Method for analyzing mucosa samples with optical coherence tomography

      A method for analyzing mucosa structure with optical coherence tomography (OCT) is provided, and includes: (a) scanning a mucosa sample with optical coherence tomography; (b) choosing a lateral range from a two- or three-dimensional OCT image and analyzing all the A-scan intensity profiles in the lateral range; (c) calculating three indicators in each A-scan intensity profile, including the standard deviation for a certain depth range below the sample surface, the exponential decay constant of the spatial-frequency spectrum and the epithelium thickness under the condition that the basement membrane is identifiable; and (d) using the three indicators of each A-scan intensity ...

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      Mentions: National Taiwan University

    2. Diagnosis of oral submucous fibrosis with optical coherence tomography

      Explore SPIE Digital Library Dentistry

      The epithelium (EP) thickness and the standard deviation (SD) of A-mode scan intensity in the laminar propria (LP) layer are used as effective indicators for the diagnosis of oral submucous fibrosis (OSF) based on the noninvasive clinical scanning of a swept-source optical coherence tomography (OCT) system of ~6 µm in axial resolution (in tissue) and 103 dB in sensitivity. Compared with the corresponding parameters in healthy oral mucosal mucosa, in OSF mucosa, the EP thickness becomes smaller and the SD of A-mode scan intensity in the LP layer (LP SD) also becomes smaller. The LP SD can also be used ...

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      Mentions: National Taiwan University Chang Gung University National Yang-Ming University

    3. Differentiating oral lesions in different carcinogenesis stages with optical coherence tomography

      Explore SPIE Digital Library Dentistry , Oncology

      A swept-source optical coherence tomography (SS-OCT) system is used to clinically scan oral lesions in different oral carcinogenesis stages, including normal oral mucosa control, mild dysplasia (MiD), moderate dysplasia (MoD), early-stage squamous cell carcinoma (ES-SCC), and well-developed SCC (WD-SCC), for diagnosis purpose. On the basis of the analyses of the SS-OCT images, the stages of dysplasia (MiD and MoD), and SCC (ES-SCC and WD-SCC) can be differentiated from normal control by evaluating the depth-dependent standard deviation (SD) values of lateral variations. In the dysplasia stage, the boundary between the epithelium (EP) and lamina propria (LP) layers can still be identified ...

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      Mentions: National Taiwan University Chang Gung University National Yang-Ming University

    4. Effective indicators for diagnosis of oral cancer using optical coherence tomography

      Explore opticsinfobase.org Dentistry
      Effective indicators for diagnosis of oral cancer using optical coherence tomography

      C. C. Yang, Meng-Tsan Tsai, Hsiang-Chieh Lee, Cheng-Kuang Lee, Chuan-Hang Yu, Hsin-Ming Chen, Chun-Pin Chiang, Cheng-Chang Chang, Yih-Ming Wang, C. C. Yang A swept-source optical coherence tomography system is used to clinically scan oral precancer and cancer patients for statistically analyzing the effective indicators of diagnosis. Three indicators are considered, including the standard deviation (SD) of an A-mode scan signal profile, the ... [Opt. Express 16, 15847-15862 (2008)]

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      Mentions: National Taiwan University
    1-4 of 4
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