1. Articles from Lindsy Peterson

    1-2 of 2
    1. Ethanol exposure alters early cardiac function in the looping heart: a mechanism for congenital heart defects?

      Ethanol exposure alters early cardiac function in the looping heart: a mechanism for congenital heart defects?

      Alcohol-induced congenital heart defects (CHDs) are frequently among the most life-threatening and require surgical correction in newborns. The etiology of these defects, collectively known as Fetal Alcohol Syndrome (FAS), has been the focus of much study, particularly involving cellular and molecular mechanisms. Few studies have addressed the influential role of altered cardiac function in early embryogenesis, due to a lack of tools with the capability to assay tiny beating hearts. To overcome this gap in our understanding, we used optical coherence tomography (OCT), a non-destructive imaging modality capable of micrometer-scale resolution imaging, to rapidly and accurately map cardiovascular structure and ...

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    2. Measuring hemodynamics in the developing heart tube with four-dimensional gated Doppler optical coherence tomography

      Measuring hemodynamics in the developing heart tube with four-dimensional gated Doppler optical coherence tomography

      Hemodynamics is thought to play a major role in heart development, yet tools to quantitatively assess hemodynamics in the embryo are sorely lacking. The especially challenging analysis of hemodynamics in the early embryo requires new technology. Small changes in blood flow could indicate when anomalies are initiated even before structural changes can be detected. Furthermore, small changes in the early embryo that affect blood flow could lead to profound abnormalities at later stages. We present a demonstration of 4-D Doppler optical coherence tomography (OCT) imaging of structure and flow, and present several new hemodynamic measurements on embryonic avian hearts at ...

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    1-2 of 2
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  2. Topics in the News

    1. (2 articles) Case Western Reserve University
    2. (1 articles) University of Bologna
    3. (1 articles) University of Cambridge
    4. (1 articles) FDA
    5. (1 articles) Notal Vision
    6. (1 articles) Topcon Medical Systems
    7. (1 articles) Tomey Corporation
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    Measuring hemodynamics in the developing heart tube with four-dimensional gated Doppler optical coherence tomography Ethanol exposure alters early cardiac function in the looping heart: a mechanism for congenital heart defects? Comparison of Anterior Segment Measurements with a New Multifunctional Unit and Five Other Devices Efficacy of Notal Vision Home OCT demonstrated by a series of scientific and clinical work Synergy Between morpHOlogical and inflammatoRy Evaluation in Predicting Long-term Coronary Plaque Progression Altered ocular microvasculature in patients with systemic sclerosis and very early disease of systemic sclerosis using optical coherence tomography angiography Assessment of macular findings by OCT angiography in patients without clinical signs of diabetic retinopathy: radiomics features for early screening of diabetic retinopathy Self-Examination Low-Cost Full-Field Optical Coherence Tomography (SELFF-OCT) for neovascular age-related macular degeneration: a cross-sectional diagnostic accuracy study The Use of Optical Coherence Tomography to Demonstrate Dark and Light Adaptation in a Live Moth Treatment of Descemet's membrane detachment after primary Descemet's stripping automated endothelial keratoplasty during surgery using intraoperative optical coherence tomography Reflectance-Based Structural Quantification of the Healthy and Glaucomatous Retinal Nerve ... Artificial Intelligence Enhances Potential of Intravascular OCT