1. Articles from Wu Jian

    1-3 of 3
    1. Different vessel response between chronic total occlusions and non-CTO lesion after Sirolimus-eluting stent implantation: a serial optical coherence tomography study

      Different vessel response between chronic total occlusions and non-CTO lesion after Sirolimus-eluting stent implantation: a serial optical coherence tomography study
      Objectives To investigate the neointimal coverage and malapposition of sirolimus-eluting stent in treatment of CTOs and non-CTO lesions (including lipid-rich plaque and non-lipid-rich plaque) by optical coherence tomography. Methods We enrolled 64 patients (CTO: n=29 stents/21 patients, lipid-rich plaque: n=33 stents/26 patients, and non-lipid-rich plaque: n=21 stents/17 patients) with 68 target vessels and examined lesion characteristics by using OCT at pre- and post-SES implantation and 6 months follow-up. Lipid rich plaque was defined as the plaque with lipid content in ≥2 quadrants. Non-lipid-rich plaque consists of fibrous, fibrocalcific plaque, and lipid plaque with less ...
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    2. High frequency of peri-strut low intensity area assessed by optical coherence tomography after polymer-based sirolimus-eluting stents implantation in porcine model

      High frequency of peri-strut low intensity area assessed by optical coherence tomography after polymer-based sirolimus-eluting stents implantation in porcine model
      Objectives To assess the frequency of peri-strut low intensity area (PLIA) in polymeric and nonpolymeric drug-eluting stents by optical coherence tomography (OCT) in porcine model, to analyse the pathological changes in PLIA. Setting Previous intravascular ultrasound studies showed that black holes were more commonly seen in sirolimus-eluting stent restenosis. Similar phenomenon (peri-strut low intensity area) was also frequently detected by OCT in DES follow-up. However, it is still largely unknown what triggers this uncommon response. Design and interventions: A total of 18 stents (BMS, n=6; polymer-free PES [PF-PES], n=6 and polymer-based SES [PB-SES], n=6) were implanted in ...
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    3. Evaluate seriate progress of vulnerable plaque by optical coherence tomography on rabbit vulnerable plaque model

      Evaluate seriate progress of vulnerable plaque by optical coherence tomography on rabbit vulnerable plaque model

      Objectives Assess seriate progress of vulnerable plaque (VP) formation fusing Optical Coherence Tomography (OCT) with histopathological test to confirm what we find in the OCT imaging of vulnerable plaque on established rabbit vulnerable plaque model. Providing early characteristics of the signals displayed by VP in order to prior recognise vulnerable people, in order to give accurate and reasonable therapy. Method 23 New Zealand white rabbits were randomly divided into 4 groups after balloon injurying the intima with subsequently 1% high fat diet. Grouping: Examed at 4 time points: 6 (n=6), 8 (n=5), 10 (n=5), 12 (n=7 ...

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    1-3 of 3
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    1. (2 articles) Harbin Medical University
    2. (1 articles) Harvard University
    3. (1 articles) Massachusetts General Hospital
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