1. Articles from Youwu He

    1-6 of 6
    1. Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal-polarization-gating optical coherence tomography

      Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal-polarization-gating optical coherence tomography

      In this study, an automatic algorithm combining an ellipsoid approximation and U-net has been presented for characterization of a zebrafish's yolk sac The polarization-difference-balanced-detection image of zebrafish was obtained based on orthogonal-polarization-gating optical coherence tomography and used to segment the yolk sac region. And ellipsoid can approximate the shape of the three-dimensional yolk sac, and the multiple parameters of volume and the three principal axes (k, l and m) can be used to quantify the yolk sac. In addition, the multiple parameters of two principal axes (l and m) and volume can distinguish the malformation from the normal controlled ...

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    2. Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo

      Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo

      We propose an orthogonal‐polarization‐gating optical coherence tomography (OPGOCT) for human sweat ducts in vivo . OPG‐OCT is composed of the orthogonal linearly polarized light of a sample arm individually interfering with orthogonal linearly polarized lights of the reference arms, where OPG‐OCT induces two images, one reflecting the projection intensity and the other the horizontal linear diattenuation (HLD). The results demonstrate that OPG‐OCT projection intensity could improve the image quality of sweat ducts. HLD also clearly illustrates the spiral shape of the sweat ducts. Finally, sweat ducts in intensity image are segmented by employing convolutional neural networks ...

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    3. Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo

      Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo

      We propose an orthogonal-polarization-gating optical coherence tomography (OPGOCT) for human sweat ducts in vivo. OPG-OCT is composed of the orthogonal linearly polarized light of a sample arm individually interfering with orthogonal linearly polarized lights of the reference arms, where OPG-OCT induces two images, one reflecting the projection intensity and the other the horizontal linear diattenuation (HLD). The results demonstrate that OPG-OCT projection intensity could improve the image quality of sweat ducts. HLD also clearly illustrates the spiral shape of the sweat ducts. Finally, sweat ducts in intensity image are segmented by employing convolutional neural networks (CNN). The proportions of left-handed ...

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    4. Reform and practice of optical coherence tomography (OCT) system-driven teaching for optoelectronic instrument principle and design

      Reform and practice of optical coherence tomography (OCT) system-driven teaching for optoelectronic instrument principle and design

      Optoelectronic instrument principle and design includes the optical, mechanical, electrical and count modules for one system. We change traditional mode of customary specialty course design for only taking the cell design ability into account. Optical coherence tomography (OCT) can provide high-resolution 3D imaging system and wide application for tissue in vivo. In this work, we carry out OCT system– driven teaching into execution in the course design teaching, and decompose OCT system into four modules for teaching progress. The reform is not only cultivating student design ability based on OCT system exploitation, improving the engineering ability, but also help scientific ...

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    5. Single camera spectral domain polarization-sensitive optical coherence tomography based on orthogonal channels by time divided detection

      Single camera spectral domain polarization-sensitive optical coherence tomography based on orthogonal channels by time divided detection

      We demonstrate a simple polarization-sensitive spectral-domain optical coherence tomography implement by using a single line-scan camera based on time divided detection. Two light shutters were placed on the dual assembly reference arm that provides a divided detection between the orthogonal vertical and horizontal polarized lights. The relative reflectivity and the retardance information were available by recombining the two orthogonal polarization images. This system can be employed to implement high speed polarization-sensitive OCT images.

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    6. Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography

      Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography
      It is imperative to evaluate the tissue wound healing response after laser irradiation so as to develop effective devices for this clinical indication, and evaluate the thermal damage degree to take appropriate treatment. In our research, we prepare 6 white rat (approximately 2 months old, weight :28±2g). Each rat was injected intraperitoneally a single dose of 2% pentobarbital sodium. After the rat was anesthetized, the two side of the rats' back were denuded and antisepsised a standardized. An Er:YAG laser (2940nm, 2.5J/cm2, single spot, 4 times) was irradiated on rat skin in vivo, and the skin ...
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    1-6 of 6
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    Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography Single camera spectral domain polarization-sensitive optical coherence tomography based on orthogonal channels by time divided detection Reform and practice of optical coherence tomography (OCT) system-driven teaching for optoelectronic instrument principle and design Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo Morphological characteristics of zebrafish's yolk sac for malformation based on orthogonal-polarization-gating optical coherence tomography Interplay between traveling wave propagation and amplification at the apex of the mouse cochlea Postdoctoral Position in Advanced Ophthalmic imaging at Johns Hopkins Revealing how maltodextrin-containing droplets dry using optical coherence tomography Repeatability and Agreement of Two Swept-Source Optical Coherence Tomographers for Anterior Segment Parameter Measurements Machine Learning Utility for Optical Coherence Tomography in Multiple Sclerosis: Is the Future Now? The Role of OCT Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis