1. Articles from Michele Reibaldi

    1-10 of 10
    1. Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study

      Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study

      Purpose To analyse the postoperative foveal avascular zone (FAZ) area, superficial vessel density (SVD) and deep vessel density (DVD) and their correlation with functional (best‐corrected visual acuity, BCVA) and anatomical outcomes (foveal macular thickness, FMT) after surgery for rhegmatogenous retinal detachment (RRD) repair. Method Patients with RRD eyes, successfully treated with a single pars plana vitrectomy (PPV) with gas tamponade and a minimum 12 months follow‐up, were re‐examined. Foveal avascular zone (FAZ) area, SVD, DVD and FMT were evaluated by using optical coherence tomography angiography (OCTA) and compared to fellow eye. Results Fifty‐six patients with macula ...

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    2. Evaluation of corneal epithelial thickness in glaucomatous patients using anterior‐segment optical coherence tomography

      Evaluation of corneal epithelial thickness in glaucomatous patients using anterior‐segment optical coherence tomography

      The corneal epithelium represents one of the main structures that undergo degenerative alterations due to antiglaucomatous therapy. Chronic glaucoma therapy containing benzalkonium chloride induces epithelial cellular changes and inflammatory infiltration that in turn causes ocular surface changes resulting in ocular discomfort. Also age‐related changes can involve the tear film stability and the corneal epithelium surface with reduction of microvilli. The objective of this study is to gain insights about the changes in corneal epithelium in glaucomatous patients divided according to age, type and duration of therapy using anterior‐segment optical coherence tomography (AS‐OCT). This study evaluated a total ...

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    3. OCT Angiography in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

      OCT Angiography in Acute Posterior Multifocal Placoid Pigment Epitheliopathy

      BACKGROUND AND OBJECTIVE: To describe retinal and choroidal findings in different stages of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). PATIENTS AND METHODS: Retrospective, noncomparative case series studied by fundus biomicroscopy, fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral-domain optical coherence tomographic (SD-OCT), and swept-source OCT angiography (SS-OCTA). RESULTS: Six eyes of three patients with bilateral APMPPE were included. FAF showed multifocal, branched patches of hyperautofluorescence with areas of hypoautofluorescence; FA disclosed early hypofluorescence, with late-phase hyperfluorescence; ICGA showed early and late-phase hypofluorescence. SD-OCT imaging revealed bilateral retinal thinning, external limiting membrane (ELM) disruption, and severe alteration ...

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    4. Dexamethasone for unresponsive diabetic macular oedema: optical coherence tomography biomarkers

      Dexamethasone for unresponsive diabetic macular oedema: optical coherence tomography biomarkers

      Purpose To analyse the effects of intravitreal dexamethasone implant (DEX) in patients with diabetic macular oedema (DME) unresponsive to ranibizumab treatment, in relation to the inflammatory optical coherence tomography (OCT) retinal features, subfoveal neuroretinal detachment (SND) and hyperreflective retinal spots (HRS). Methods Patients with DME poorly responsive to three injections of ranibizumab were treated with DEX. Best‐corrected visual acuity (BCVA) and central macula thickness (CMT, measured by Spectralis SD‐OCT) were assessed at baseline and at 1, 3, and 6 months. Results Overall, 44 eyes were included in the study. In the whole group, mean BCVA (baseline 51.5 ...

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    5. Choroidal neovascularization due to choroidal osteoma treated with anti–vascular endothelial growth factor therapy: An optical coherence tomography angiography study

      Choroidal neovascularization due to choroidal osteoma treated with anti–vascular endothelial growth factor therapy: An optical coherence tomography angiography study

      Purpose: To evaluate the response to anti–vascular endothelial growth factor therapy for choroidal neovascularization secondary to choroidal osteoma using optical coherence tomography angiography. Methods: This retrospective study included four eyes of four females with choroidal osteoma complicated by choroidal neovascularization, treated with ranibizumab. All patients underwent full ophthalmologic examination, including ocular ultrasound, retinography, fluorescein angiography, spectral-domain or swept-source optical coherence tomography, and optical coherence tomography angiography. These images were analyzed to measure choroidal osteoma and to study choroidal neovascularization changes after intravitreal anti–vascular endothelial growth factor. Results: In all cases, fluorescein angiography revealed the presence the choroidal neovascularization ...

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    6. Optical coherence tomography angiography in pre-perimetric open-angle glaucoma

      Optical coherence tomography angiography in pre-perimetric open-angle glaucoma

      Purpose To evaluate the diagnostic efficacy of optical coherence tomography (OCT) angiography, in patients with pre-perimetric open-angle glaucoma. Methods Thirty-eight consecutive eyes of 26 patients with pre-perimetric open-angle glaucoma and 48 normal eyes of 32 controls were included in this prospective study. We evaluated OCT angiography, spectral-domain OCT and visual fields parameters. Differences between controls and patients and between OCT angiography parameters and traditional glaucoma measurements were evaluated. Receiver operating characteristic curves for OCT angiography parameters were assessed. Results The flow index ( p = 0.021) and vessel density ( p = 0.001) were significantly lower in pre-perimetric glaucoma eyes versus normal ...

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    7. Optic nerve head in central retinal vein occlusion by spectral-domain OCT

      Optic nerve head in central retinal vein occlusion by spectral-domain OCT

      To evaluate the morphology of optic nerve head by spectral-domain optical coherence tomography (SD-OCT) in patients with unilateral central retinal vein occlusion (CRVO). In 39 consecutive patients with unilateral CRVO and 39 healthy controls, morphologic parameters of optic nerve head were assessed in both eyes by Spectralis SD-OCT using a custom radial B-scan pattern. The length of Bruch membrane opening (BMO) was measured in OCT scans, and optic disc diameters (DD) were assessed in infrared fundus photographs. Axial length was determined by IOLMaster. The BMO length was measured in all eyes with CRVO, while DD was not assessed in 9 ...

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    8. Intrasession Reproducibility of RNFL Thickness Measurements Using SD-OCT in Eyes With Keratoconus

      Intrasession Reproducibility of RNFL Thickness Measurements Using SD-OCT in Eyes With Keratoconus

      BACKGROUND AND OBJECTIVE: To evaluate the intrasession reproducibility of the peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained by spectral-domain optical coherence tomography (SD-OCT) in eyes with keratoconus and normal eyes. PATIENTS AND METHODS: Peripapillary RNFL thickness measurements with SD-OCT were repeated three times during the same visit using the eye tracker and retest function in one eye of each participant. Reproducibility was evaluated using within-subject standard deviation (Sw), coefficient of variation (CV), and intraclass correlation coefficient (ICC). RESULTS: For the overall global RNFL thickness, the values of the three parameters were Sw (± 1.96 standard error) 1.43 ...

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    9. Ten Years of Severe Vitreomacular Traction Syndrome without Functional Damage Demonstrated by Optical Coherence Tomography

      Ten Years of Severe Vitreomacular Traction Syndrome without Functional Damage Demonstrated by Optical Coherence Tomography
      To describe anatomical and functional features in one patient with 10 years of severe vitreomacular traction syndrome (VTS) without functional damage demonstrated by optical coherence tomography (OCT). Patient and Methods. One patient with a history of 10 years VTS, with best-corrected visual acuity of 20/32, was followed up with OCT. Follow-up examinations, 3months for the first year after diagnosis and every 6 months for the subsequent years, were performed. Results. Follow-up examinations showed no change anatomically and functionally. Far and near visual acuity was unchanged. OCT by Heidelberg Spectralis did not evidence differences from Stratus OCT images. Conclusion. VTS ...
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    10. Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Idiopathic Macular Hole: A Cross-sectional Prospective Study

      Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Idiopathic Macular Hole: A Cross-sectional Prospective Study
      Purpose:: To determine the choroidal thickness in the macular area in patients with idiopathic macular hole in one eye and an unaffected fellow eye and in healthy controls.Design:: Cross-sectional, prospective study.Methods:: Twenty-two patients with a full-thickness unilateral idiopathic macular hole and 22 age- and sex-matched controls were recruited. Enhanced depth imaging optical coherence tomography images were obtained by using spectral-domain optical coherence tomography. The choroidal thickness was measured in the subfoveal area and 1000 μm and 2000 μm away from the fovea in the nasal and temporal regions. The diameter of the macular hole and the axial length ...
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    1-10 of 10
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    Enhanced Depth Imaging Optical Coherence Tomography of the Choroid in Idiopathic Macular Hole: A Cross-sectional Prospective Study Ten Years of Severe Vitreomacular Traction Syndrome without Functional Damage Demonstrated by Optical Coherence Tomography Intrasession Reproducibility of RNFL Thickness Measurements Using SD-OCT in Eyes With Keratoconus Optic nerve head in central retinal vein occlusion by spectral-domain OCT Optical coherence tomography angiography in pre-perimetric open-angle glaucoma Choroidal neovascularization due to choroidal osteoma treated with anti–vascular endothelial growth factor therapy: An optical coherence tomography angiography study Dexamethasone for unresponsive diabetic macular oedema: optical coherence tomography biomarkers OCT Angiography in Acute Posterior Multifocal Placoid Pigment Epitheliopathy Evaluation of corneal epithelial thickness in glaucomatous patients using anterior‐segment optical coherence tomography Vascular changes after vitrectomy for rhegmatogenous retinal detachment: optical coherence tomography angiography study KU Leuven leads €6 million research project on heart disease and dementia Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed