1. Articles from H. Ullah

    1-8 of 8
    1. Fundamentals of Optical Coherence Tomography: A Critical Review

      Fundamentals of Optical Coherence Tomography: A Critical Review

      The main objective of this work is to go through fundamentals, mechanism and types of state of the art emerging imaging modality, i.e. optical coherence tomography (OCT) for non-invasive 3D imaging of bio tissues. This work consists of a critical literature study of OCT’s contribution to axial scanning of bio tissues using different types to the best of our knowledge. Doppler optical coherence tomography (D-OCT) and speckle variance optical coherence tomography (SVOCT) for blood flow assessment and blood microvasculatures on micron-scale resolution with dorsal skin-fold window chamber model (WCM) of mouse, and Fourier domain common path (FD-CP-OCT) for ...

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    2. Autocorrelation optical coherence tomography for glucose quantification in blood

      Autocorrelation optical coherence tomography for glucose quantification in blood

      We report a new method for glucose monitoring in blood tissue based on the autocorrelation function (ACF) analysis in Fourier domain optical coherence tomography (FD-OCT). We have determined the changes in OCT monitoring signals' depth to characterize the modulations in ACFs for quantitative measurements of glucose concentrations in blood. We found that an increase in the concentration of glucose in blood results in decreased OCT monitoring signal due to the increase in the refractive index of the media.

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    3. Monitoring of glucose levels in mouse blood with noninvasive optical methods

      Monitoring of glucose levels in mouse blood with noninvasive optical methods

      We report the quantification/monitoring of glucose levels in a blood sample using optical diffuse reflectance (ODR) underlying variations in optical parameters with a white light source (at peak wavelength ~600 nm and range 450–850 nm) and in blood in vivo using M-mode optical coherence tomography (OCT) in terms of the translational diffusion coefficient ( D T ). In the ODR experiments, we have investigated two types of mono-dispersive particles, i.e. polystyrene microspheres (PMSs) with diameters of 1.4 μ m (variable concentrations) and 2.6 μ m (fixed concentration) in a water phantom by observing changes in the reduced scattering coefficient ...

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    4. M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

      M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study

      We report the use of M-mode swept source optical coherence tomography (SS-OCT) for measuring sodium chloride (NaCl) salt concentrations in liquid phantoms and in drawn whole blood based on temporal dynamics of light scattering. The Brownian motion of scattering particle is affected due to the change in viscosity of liquid. An autocorrelation function was determined from the power spectrum of SS-OCT signal and then was fit by mono and double exponential function to obtain decorrelation time. These translational decorrelation times corresponding to translational diffusion coefficients enabled us to find the controlled viscosity of the medium. The viscosities of the media ...

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    5. Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography

      Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography

      Abstract  The increase of glucose levels in blood changes the viscosity of flowing fluids and shape of the erythrocytes. Both of these can affect the details of light scattering as can be quantified via decorrelation times measured by optical coherence tomography (OCT). The relative contributions of these competing effects have been studied by examining the motion dynamics of deformable asymmetrical (red blood cells, RBCs with ∼7 μm diameter and ∼2 μm thickness) and non deformable symmetrical (polystyrene microspheres, PSM with 1.4 μm diameter) flowing scattering particles. The fluid flow under the action of gravity was modulated by changing the ...

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    6. Can temporal analysis of optical coherence tomography statistics report on dextrorotatory-glucose levels in blood?

      Can temporal analysis of optical coherence tomography statistics report on dextrorotatory-glucose levels in blood?
      We report the use of optical coherence tomography (OCT) for measuring dextrorotatory-glucose (D-glucose) in liquid phantoms and in drawn blood based on temporal dynamics of light scattering. The presence of D-glucose alters the medium viscosity, thus affecting the Brownian motion of the scatterers (polystyrene microspheres (PMS) in phantoms, red blood cells (RBCs) in blood) as measured by OCT. To quantify the effect, the signal autocorrelation functions were measured from M-mode OCT data and exponentially fit to obtain the decorrelation times. These were then related to translational (and rotational, in case of asymmetric scatterers) diffusion coefficients which enabled the determination of ...
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    7. Catheters for optical coherence tomography

      Catheters for optical coherence tomography

      The objective of this review article is to overview technology, clinical evidence, and future applications to date optical coherence tomography (OCT) probes to yield the diagnostic purpose. We have reviewed the designing, construction and working of different categories of OCT probes developed for optical diagnostics having a potential for non invasive and improved detection of different types of cancer as well as other neoplasm. Rotational and balloon catheters, imaging needles and hand-held, linear scanning, multichannel, micro electro mechanical systems (MEMS) technology based, dynamic focusing, forward view imaging, and common path interferometer based probes have been discussed in details. The fiber ...

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    8. Catheters for optical coherence tomography

      Catheters for optical coherence tomography
      The objective of this review article is to overview technology, clinical evidence, and future applications to date optical coherence tomography (OCT) probes to yield the diagnostic purpose. We have reviewed the designing, construction and working of different categories of OCT probes developed for optical diagnostics having a potential for non invasive and improved detection of different types of cancer as well as other neoplasm. Rotational and balloon catheters, imaging needles and hand-held, linear scanning, multichannel, micro electro mechanical systems (MEMS) technology based, dynamic focusing, forward view imaging, and common path interferometer based probes have been discussed in details. The fiber ...
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    1-8 of 8
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  2. Topics in the News

    1. (6 articles) National Institutes of Health
    2. (4 articles) University of Toronto
    3. (2 articles) Ryerson University
    4. (2 articles) I. Alex Vitkin
    5. (2 articles) UC Irvine
    6. (2 articles) Oregon Health & Science University
    7. (2 articles) Zhongping Chen
    8. (2 articles) Yifan Jian
    9. (2 articles) Heidelberg Engineering
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    12. (1 articles) University of Houston
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    Catheters for optical coherence tomography Can temporal analysis of optical coherence tomography statistics report on dextrorotatory-glucose levels in blood? Quantification of glucose levels in flowing blood using M-mode swept source optical coherence tomography M-mode swept source optical coherence tomography for quantification of salt concentration in blood: An in vitro study Catheters for optical coherence tomography Monitoring of glucose levels in mouse blood with noninvasive optical methods Autocorrelation optical coherence tomography for glucose quantification in blood Fundamentals of Optical Coherence Tomography: A Critical Review The Effect of Anti-Tubercular Drugs on Retinal Nerve Fiber Layer Thickness Using Optical Coherence Tomography A Cross-sectional Optical Coherence Tomography Study in Patients on Taxane-based Therapy and A Case Report with the Literature Review Association of systemic inflammatory biomarkers with morphological characteristics of the coronary atherosclerotic plaque by intravascular optical coherence tomography. OCT angiography improves views of retina blood flow