1. Articles from kaori sayanagi

    1-16 of 16
    1. Time course of swept-source optical coherence tomography angiography findings after photodynamic therapy and aflibercept in eyes with age-related macular degeneration

      Time course of swept-source optical coherence tomography angiography findings after photodynamic therapy and aflibercept in eyes with age-related macular degeneration

      Purpose To report swept-source optical coherence tomography angiography (SS-OCTA) findings after full-fluence photodynamic therapy (PDT) and aflibercept intravitreal injection (IVA) for age-related macular degeneration (AMD). Methods Five eyes of five patients with AMD treated with PDT and IVA were include into the study. We retrospectively reviewed the data obtained from the five patients using SS-OCTA before and after treatment. Three eyes had type 1 choroidal neovascularization (CNV) and two eyes had polypoidal choroidal vasculopathy. Results Before treatment, the CNV signals detected in all cases, decreased in three eyes and were not detected completely in two eyes at 1 months after ...

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      Mentions: Osaka University
    2. Evaluation of retinal nonperfusion in branch retinal vein occlusion using wide‐field optical coherence tomography angiography

      Evaluation of retinal nonperfusion in branch retinal vein occlusion using wide‐field optical coherence tomography angiography

      Purpose To characterize wide‐field optical coherence tomography angiography (OCTA) features of retinal nonperfusion in eyes with branch retinal vein occlusion (BRVO). Methods Automated scanning of five 12 × 12‐mm areas of swept‐source OCTA and wide‐field fluorescein angiography (FA) images was performed in a consecutive case series of 27 eyes in 27 patients with BRVO in this institutional cross‐sectional study. The correlation between the areas of retinal nonperfusion detected by both examinations was assessed. Panoramic images obtained in five 12 × 12‐mm OCTA scans in eyes with retinal nonperfusion were binarized or skeletonized, and the associations between ...

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    3. An Optical Coherence Tomography Angiography Study

      An Optical Coherence Tomography Angiography Study

      Purpose: To investigate vascular perfusion and foveal avascular zone area in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) after intravitreal aflibercept therapy in central retinal vein occlusion eyes and their association with best-corrected visual acuity. Methods: Thirty-five subjects with central retinal vein occlusion and macular edema were evaluated. After macular edema resolution following intravitreal aflibercept , subjects underwent optical coherence tomography angiography to measure SCP and DCP perfusion and the foveal avascular zone within a 3 × 3-mm area. Correlations between best-corrected visual acuity and optical coherence tomography angiography measurements were examined. Results: After intravitreal aflibercept therapy, mean retinal ...

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    4. RETINAL MICROVASCULATURE AND VISUAL ACUITY AFTER INTRAVITREAL AFLIBERCEPT IN EYES WITH CENTRAL RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study

      RETINAL MICROVASCULATURE AND VISUAL ACUITY AFTER INTRAVITREAL AFLIBERCEPT IN EYES WITH CENTRAL RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study

      Purpose: To investigate vascular perfusion and foveal avascular zone area in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) after intravitreal aflibercept therapy in central retinal vein occlusion eyes and their association with best-corrected visual acuity. Methods: Thirty-five subjects with central retinal vein occlusion and macular edema were evaluated. After macular edema resolution following intravitreal aflibercept, subjects underwent optical coherence tomography angiography to measure SCP and DCP perfusion and the foveal avascular zone within a 3 x 3-mm area. Correlations between best-corrected visual acuity and optical coherence tomography angiography measurements were examined. Results: After intravitreal aflibercept therapy, mean ...

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      Mentions: Osaka University
    5. Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography

      Retinal Microvasculature and Visual Acuity in Eyes With Branch Retinal Vein Occlusion: Imaging Analysis by Optical Coherence Tomography Angiography

      Purpose : To investigate microvascular changes in the superficial capillary plexus (SCP) and deep capillary plexus (DCP) in eyes with resolved branch retinal vein occlusion (BRVO) and their association with best-corrected visual acuity (BCVA). Methods : Eighty-five eyes (82 consecutive patients) with BRVO after resolution of the macular edema were retrospectively evaluated. All patients underwent optical coherence tomography angiography (OCTA) for assessment of microvascular changes, including capillary telangiectasia, microaneurysm, and disruption of the foveal avascular zone (FAZ). The areas of vascular perfusion and FAZ in the SCP and DCP were quantitatively evaluated. Best-corrected visual acuity was measured on the same day as ...

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    6. En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      Aim To observe the choroidal microstructure in polypoidal choroidal vasculopathy (PCV) using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source that visualises tissue beneath the retinal pigment epithelium (RPE) and deep choroid, and to compare the findings with those of indocyanine green angiography (ICGA). Methods In this retrospective, non-invasive, observational case series, 19 eyes (18 patients) with PCV were observed using HP-OCT (swept source, 100 000 A-scans/s, 1060 nm wavelength) and ICGA. The HP-OCT scan protocol was a 3×3-mm or 6×6-mm square containing 256×256 or 512×128 A-scans. The choroidal thickness (CT) was measured ...

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    7. Pathology detection rate of spectral domain optical coherence tomography devices

      Pathology detection rate of spectral domain optical coherence tomography devices

      Background Spectral domain optical coherence tomography (SDOCT) allows for higher resolution scans and higher scanning speeds compared to time domain OCT (TDOCT). The purpose of this study is to compare the pathology detection rates of various SDOCT devices to the Stratus TDOCT. Methods Patients with neovascular age-related macular degeneration were imaged on the Stratus and one of four SDOCT devices. The images were then analysed in a masked manner evaluating for the presence of epiretinal membrane (ERM), pigment epithelial detachment (PED) and subretinal fluid (SRF). After determining that low scan density with one of the devices was likely the cause ...

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    8. Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy

      Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy

      Background We compared the visibility of retinal and choroidal pathologies using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source (1,050 nm) and conventional spectral-domain OCT (SD-OCT) in age-related macular degeneration (AMD). Methods One hundred and forty-six eyes were included: 63 eyes with AMD, 79 eyes with polypoidal choroidal vasculopathy (PCV), and four eyes with retinal angiomatous proliferation. The SD-OCT and HP-OCT images were compared using the grading criteria to grade the visibility of the retinal changes, the line corresponding to the retinal pigment epithelium (RPE), and the chorioscleral interface (CSI). In 132 eyes with a pigment epithelial ...

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    9. 3D Spectral domain optical coherence tomography findings in choroidal tumors

      3D Spectral domain optical coherence tomography findings in choroidal tumors
      Purpose. To report the optical coherence tomographic features differentiating choroidal nevus from choroidal melanoma by 3D spectral-domain optical coherence tomography (SD-OCT) and OCT characteristics of other choroidal tumors. Methods. A total of 67 consecutive eyes with choroidal tumors including choroidal nevus (25 eyes), indeterminate choroidal melanocytic lesion (11 eyes), malignant melanoma (23 eyes), metastasis (4 eyes), hemangioma (2 eyes), and osteoma (2 eyes) were imaged with 3D SD-OCT (OCT-1000; Topcon Inc., Paramus, NJ). The images were analyzed for the presence or absence of SD-OCT findings such as retinal pigment epithelium (RPE)/choriocapillaris reflectivity, RPE irregularity, drusen, sub-RPE fluid, RPE thickness ...
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    10. Spectral-Domain Optical Coherence Tomographic Findings in Myopic Foveoschisis

      Purpose: The purpose of this study was to investigate the sensitivity of various scan modes of spectral-domain optical coherence tomography (SD-OCT) for detecting pathologies that may accompany myopic foveoschisis, which is important for making surgical decisions and planning surgical strategies for myopic foveoschisis. Methods: Twenty-one eyes of 18 patients were diagnosed with myopic foveoschisis by SD-OCT. Patients were examined with SD-OCT using both a five-line raster scan and a three-dimensional scan at the same visit. The detection rates of pathologies such as macular hole, epiretinal membrane, retinal vascular microfolds, internal limiting membrane detachment, paravascular microhole, and photoreceptor inner and outer ...
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    11. Fourier domain optical coherence tomographic and auto-fluorescence findings in indeterminate choroidal melanocytic lesions

      Aim To compare detection rates of drusen and subretinal fluid by Fourier domain optical coherence tomography (FD OCT) and orange pigment by fundus autofluorescence (FAF) with ophthalmoscopy in indeterminate choroidal melanocytic lesions. Methods In a consecutive case series of 38 patients with indeterminate choroidal melanocytic lesion that would have been categorised as a small tumour according to the size-based nomenclature used in the Collaborative Ocular Melanoma Study, each eye was submitted to ophthalmoscopic examination, FD OCT and FAF. The presence of drusen, subretinal fluid and orange pigment was recorded for each lesion by a single observer at the time of ...
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    12. Fourier Domain Optical Coherence Tomographic and Auto-Fluorescence Findings in Choroidal Melanocytic Lesions

      Purpose: To compare detection rates of drusen and subretinal fluid by Fourier domain optical coherence tomography (FD OCT) and orange pigment by fundus autofluorescence (FAF) with ophthalmoscopy in indeterminate choroidal melanocytic lesions. Methods: In a consecutive case series of 38 patients with indeterminate choroidal melanocytic lesion that would have been categorized as small tumor according to the size-based nomenclature used in the Collaborative Ocular Melanoma Study, each eye was submitted to ophthalmoscopic examination, FD OCT and FAF. The presence of drusen, subretinal fluid, and orange pigment was recorded for each lesion by a single observer at the time of initial ...
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    13. Comparison of Retinal Thickness Measurements Between Three-dimensional and Radial Scans on Spectral-Domain Optical Coherence Tomography

      Purpose: To compare retinal thickness (RT) measurements between traditional 6 radial line scans and three-dimensional (3D) scans using spectral-domain optical coherence tomography (SD-OCT).Design: Prospective, consecutive case series.Methods: Twenty eyes of 17 patients with macular diseases and 8 healthy subjects were scanned using 2 different methods (3D scan and 6 radial line scan) using 2 different SD-OCT devices (Topcon OCT-1000 [Topcon Inc, Paramus, New Jersey, USA] and Canon SPOCT [(Canon/Optopol Inc, Depew, New York, USA]) by an experienced OCT operator. In 16 eyes, the data of TD-OCT were also obtained for comparison. The RT in 9 regions based ...
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    14. Spectral-Domain Optical Coherence Tomography Findings After Indocyanine Green-Assisted Vitrectomy For Idiopathic Macular Hole.

      Purpose: To report the intraretinal changes seen on the spectral-domain optical coherence tomography after indocyanine green (ICG) assisted internal limiting membrane peeling for macular hole. Methods: A 76-year-old woman with closed macular hole after ICG-assisted internal limiting membrane peeling presented poor visual acuity. Infrared-red, fundus autofluorescence, ICG fluorescence, time-domain OCT and spectral-domain optical coherence tomography images were obtained. Results: Spectral-domain optical coherence tomography showed the irregular bumps of the retinal pigment epithelium, thinning of the overlying photoreceptor inner and outer segment layer, and enhanced reflectivity of external limiting membrane layer that corresponded to residual ICG fluorescence dots. The area of ...
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    15. Comparison of Spectral-Domain versus Time-Domain Optical Coherence Tomography in Management of Age-Related Macular Degeneration with Ranibizumab

      Purpose: To compare the ability to delineate and detect patterns of choroidal neovascularization (CNV) activity in patients with exudative age-related macular degeneration (AMD) after ranibizumab treatment between time-domain optical coherence tomography (TD-OCT) and 4 different spectral-domain optical coherence tomography (SD-OCT) devices. Design Prospective, consecutive case series. Participants Sixty-one eyes of 58 patients with exudative AMD after ranibizumab treatment were included in this study. Methods All patients were imaged with TD-OCT and at least 1 of 4 different SD-OCT devices at the same visit after ranibizumab treatment. The OCT images were analyzed in a masked fashion by 2 independent graders (KS ...
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    16. Spectral Domain Optical Coherence Tomography and Fundus Autofluorescence Findings in Pseudoxanthoma Elasticum

      A 39-year-old man with pseudoxanthoma elasticum who had a loss of vision was examined using digital imaging. Spectral domain optical coherence tomography (SD-OCT) detected subfoveal deposits that coincided with hyperautofluorescent areas on fundus autofluorescence imaging. These deposits seemed to cause the patient’s rapid visual loss because no angioid streaks or choroidal neovascularization were present in the fovea. These deposits were not observed on fundus and infrared photography. SD-OCT combined with fundus autofluorescence imaging may be a useful tool for diagnosis of the atypical deposits in patients with pseudoxanthoma elasticum, which could lead to visual loss. [Ophthalmic Surg Lasers Imaging ...
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    1-16 of 16
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