1. Articles from giuseppe de crecchio

    1-11 of 11
    1. Optical Coherence Tomography Angiography to Assess Vascular Remodeling of the Choriocapillaris After Low-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

      Optical Coherence Tomography Angiography to Assess Vascular Remodeling of the Choriocapillaris After Low-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

      Background To evaluate the efficacy of optical coherence tomography angiography (OCTA) in identifying changes in the choriocapillaris layer after low-fluence verteporfin photodynamic therapy (vPDT) in patients affected by chronic central serous chorioretinopathy (CSCR). Methods Low-fluence vPDT was performed on 28 eyes of 27 patients with CSCR. All patients underwent the following tests at baseline and 6 months after treatment: best corrected visual acuity (BCVA), fluorescein angiography, indocyanine green angiography, enhanced depth imaging OCT and OCTA. Results Subretinal fluid was completely absorbed in 18 of the 28 affected eyes (64.3%) after low-fluence vPDT (“responders”), and incompletely absorbed in 10 eyes ...

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    2. Optical coherence tomography angiography in myopic choroidal neovascularization after intravitreal ranibizumab

      Optical coherence tomography angiography in myopic choroidal neovascularization after intravitreal ranibizumab

      Purpose: To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. Methods: Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25 ± 9.63 years) for a total of 20 eyes examined (14 right eyes, 6 left eyes). Images were analyzed independently by two examiners. Results: Mean follow-up was 5.75 ± 1.88 months, with a mean intravitreal injections of 1.90 ± 0.44. Mean best-corrected visual acuity at baseline was 0.39 ± 0.18 logMAR versus 0.26 ± 0.16 logMAR 6 ...

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    3. Optical coherence tomography angiography in retinal cavernous hemangioma

      Optical coherence tomography angiography in retinal cavernous hemangioma

      Cavernous hemangiomas of the retina are rare benign vascular tumors, commonly diagnosed in children and young adults. They are characterized by dilated blood vessels that form cavities or caverns through which the blood flow is very low or virtually absent [1] . Retinal lesions may be associated with cerebral hemangiomas [1] , which conversely, do not harbor any tissue within the malformation, the smooth muscle is impaired and there is no capsule surrounding the caverns. Cavernous hemangioma has also been associated with choroidal hemangioma [2] and ocular melanocytosis [3] . Retinal lesions vary in size and location, and generally follow the course of ...

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    4. Optical coherence tomography angiography in incomplete acute Vogt-Koyanagi-Harada disease

      Optical coherence tomography angiography in incomplete acute Vogt-Koyanagi-Harada disease

      Dear Editor, Vogt-Koyanagi-Harada (VKH) disease is a cell-mediated autoimmune syndrome directed against melanocytes. It is considered a multisystem disorder characterized by granulomatous panuveitis often associated with neurologic and cutaneous manifestations. The choroid is the main site of autoimmune inflammation in ocular tissues[1]. Here we report the case of a 48-year-old woman with diminished vision that began about 15d earlier. The patient has consented to the submission of this Letter for submission to the journal. Her visual acuity was 0.8 in both eyes. She also suffered from headache and hearing loss, and reported a bout of influenza some days ...

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    5. Study of the Radial Peripapillary Capillary Network in Congenital Optic Disc Anomalies with Optical Coherence Tomography Angiography

      Study of the Radial Peripapillary Capillary Network in Congenital Optic Disc Anomalies with Optical Coherence Tomography Angiography

      Abstract Purpose To evaluate the radial peripapillary capillary network with optical coherence tomography angiography (angio-OCT) in morning glory syndrome (MGS), optic disc colobomas and optic disc pits, and to explore possible correlations between the neural vascular structure and the pathogenesis of congenital optic disc anomalies. Design Prospective observational comparative case series. Methods Fifteen eyes of 15 patients with congenital optic disc anomalies were enrolled in this study. All patients underwent angio-OCT. The scans were centered on optic discs. Results The mean age at presentation was 33 years (range: 19–50 years). Congenital optic disc anomalies were identified in all 15 ...

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    6. Optical coherence tomography angiography versus fluorescein angiography in the diagnosis of ischaemic diabetic maculopathy

      Optical coherence tomography angiography versus fluorescein angiography in the diagnosis of ischaemic diabetic maculopathy

      Purpose To evaluate the efficacy of optical coherence tomography (OCT) angiography versus fluorescein angiography (FA) in terms of retinal vessel imaging in ischaemic diabetic maculopathy defined according to the Early Treatment Diabetic Retinopathy Study (ETDRS) classification. Methods Twenty patients (31 eyes) with ischaemic diabetic maculopathy and 17 control subjects (27 eyes) were enrolled in this prospective study. Patients and control subjects underwent complete ophthalmic examination, including best-corrected visual acuity (BCVA), intraocular pressure, FA, Fourier domain optical coherence tomography (FD-OCT) and OCT angiography. Fluorescein angiograms and OCT angiography images were graded according to the foveal avascular zone (FAZ) of the ETDRS ...

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    7. Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry

      Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry

      Objective To evaluate the efficacy of high-speed Fourier-domain optical coherence tomography (FD-OCT) and fundus microperimetry (MP-1) in identifying the anatomic and functional features of ischemic diabetic maculopathy. Design Prospective noninterventional study. Participants Forty-two consecutive eyes (23 patients) with ischemic diabetic maculopathy and 40 normal eyes (25 control subjects) were included in this study. Methods Best corrected visual acuity, ganglion cell complex (GCC) thickness measured with FD-OCT, and central light sensitivity recorded with MP-1 were evaluated. Results GCC thickness and light sensitivity were significantly reduced in all affected eyes versus control eyes. logMAR BVCA was significantly correlated with mean macular sensitivity ...

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    8. Choroidal Thickness in Open-Angle Glaucoma Measured by Spectral-Domain Scanning Laser Ophthalmoscopy/Optical Coherence Tomography

      Choroidal Thickness in Open-Angle Glaucoma Measured by Spectral-Domain Scanning Laser Ophthalmoscopy/Optical Coherence Tomography

      Aims: To measure macular choroidal thickness in healthy and glaucomatous eyes using spectral-domain scanning laser ophthalmoscopy/optical coherence tomography. Methods: Choroidal thickness was measured in 21 healthy eyes and 16 glaucomatous eyes. Choroidal thickness was measured under the fovea and at 500-µm intervals from the foveal center to 4 mm in the nasal and temporal directions. Vessels were counted in a macular area of 8,000 µm2. Only choroidal vessels with a horizontal diameter of at least 155 µm and a vertical diameter of at least 50 µm were considered. Results: The mean choroidal thickness was greatest below the fovea ...

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    9. Evaluation of Morning Glory Syndrome with Spectral Optical Coherence Tomography and Echography

      Purpose: To evaluate eyes affected by morning glory syndrome (MGS) with spectral-domain optical coherence tomography (SD OCT) and echography.Design: Prospective case series.Participants: Nineteen patients (22 eyes) with MGS observed at the Eye Department, University of Naples Federico II, Naples, Italy.Methods: All patients underwent a complete ophthalmologic examination that included best-correct visual acuity, fundus photography, and echography. Nine patients underwent SD OCT and high-frequency B-scan echography (20 MHz).Main Outcome Measures: Spectral-domain optical coherence tomography and echographic findings in MGS.Results: Spectral-domain optical coherence tomography revealed retinal detachment in the conus area of 5 eyes: 4 with noncontractile ...
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    10. Three-dimensional Visualization of Vitreoretinal Abnormalities in High Myopia

      The authors have evaluated with three-dimensional (3D) spectral domain optical coherence tomography (SD-OCT) four highly myopic eyes (2 patients) presenting with peripapillary detachment of the pigment epithelium (PDPM), vitreoretinal tractions, and myopic retinoschisis. Three-dimensional SD-OCT analysis of PDPM revealed an optically empty space localized beneath the retinal pigment epithelium (RPE). A peripapillary separation of the retina-RPE complex from the choroid could explain the presence of this space. The 3D imaging of vitreomacular tractions could help physicians plan the appropriate surgical approach in patients with myopic posterior detachment due to macular hole. [Ophthalmic Surg Lasers Imaging 2008;39:S86-S89.]
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    11. En Face Optical Coherence Tomography of the Posterior Pole in High Myopia

      Purpose To evaluate a large series of patients affected by high myopia using multiplanar imaging provided by en face optical coherence tomography (OCT). Design Observational cross-sectional study. Methods En face OCT longitudinal cross-sectional B scans and coronal C scans were obtained in 200 eyes of 100 patients with myopia greater than –6 diopters and evidence of posterior staphyloma at fundus examination and at ultrasound B-scan evaluation. Results A macular hole was present in three eyes (1.5%). We detected posterior retinal detachment in 37 cases (18.5%). In 15 eyes (7.5%) detachment was associated with a macular hole. In ...
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    1-11 of 11
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    Choroidal Thickness in Open-Angle Glaucoma Measured by Spectral-Domain Scanning Laser Ophthalmoscopy/Optical Coherence Tomography Evaluation of ischemic diabetic maculopathy with Fourier-domain optical coherence tomography and microperimetry Optical coherence tomography angiography versus fluorescein angiography in the diagnosis of ischaemic diabetic maculopathy Study of the Radial Peripapillary Capillary Network in Congenital Optic Disc Anomalies with Optical Coherence Tomography Angiography Optical coherence tomography angiography in incomplete acute Vogt-Koyanagi-Harada disease Optical coherence tomography angiography in retinal cavernous hemangioma Optical Coherence Tomography Angiography to Assess Vascular Remodeling of the Choriocapillaris After Low-Fluence Photodynamic Therapy for Chronic Central Serous Chorioretinopathy AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography Motorized capsule for shadow-free OCT imaging and synchronous beam control Notal Vision Diagnostic Clinic reports completion of 6 million ForeseeHome AMD home-monitoring tests Monitoring retinal responses to acute intraocular pressure elevation in rats with visible light optical coherence tomography Optical Coherence Tomography-Angiography of Different Choroidal Neovascularization Subtypes in Wet Age-related Macular Degeneration