1. Articles from akitoshi yoshida

    1-18 of 18
    1. Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study

      Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study

      To use a Doppler optical coherence tomography (DOCT) flowmeter to investigate segmental retinal blood flow (RBF) and sum of the segmental RBFs (SRBF) changes after panretinal photocoagulation (PRP) was used to treat type 2 diabetes mellitus with severe diabetic retinopathy (DR). Data from five patients with proliferative DR (PDR) (mean age 51.9 ± 10.5 years) was analyzed. The vessel diameter (D), average velocity (V), and retinal blood flow (RBF) in veins were measured using a DOCT flowmeter before and four weeks after PRP. Segmental RBF from inferotemporal (IT), superotemporal (ST), inferonasal (IN), and superonasal (SN) veins were measured, and ...

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    2. Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects

      Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects

      Purpose : To evaluate the repeatability and reproducibility of retinal blood flow (RBF) measurements in humans by using new auto-alignment and measurement software in a commercially available Doppler optical coherence tomography (DOCT) system. Methods : The DOCT flowmeter assessed the intrasession repeatability and the intersession and interobserver reproducibility of the RBF measurements. For intrasession repeatability, the coefficients of variation (CVs) of five repeated RBF measurements were calculated at the retinal arteries and veins in 20 normal eyes of 20 healthy volunteers. For intersession reproducibility, two sets of three measurements obtained by one observer on 2 different days were compared. For interobserver reproducibility ...

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    3. Abnormality of retinal arterial velocity profiles using Doppler Fourier-domain optical coherence tomography in a case of Takayasu's arteritis with aortic regurgitation

      Abnormality of retinal arterial velocity profiles using Doppler Fourier-domain optical coherence tomography in a case of Takayasu's arteritis with aortic regurgitation

      Purpose To evaluate the retinal microcirculation using a segmental-scanning Doppler optical coherence tomography (DOCT) flowmeter in a patient with Takayasu's arteritis (TA) with aortic valve regurgitation (AR). Observations We measured the retinal blood velocity (V), retinal blood flow (RBF), and retinal blood velocity profiles (RBVP) of the major retinal arterioles using a DOCT flowmeter. The arteries were measured at the straight portion 1 disc diameter from the optic disc. Horizontal velocity profiles were extracted to evaluate the RBVP during one cardiac cycle. A patient with TA with stage 2 Takayasu retinopathy (TR) and AR, had normal RBF and V ...

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    4. Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography

      Characteristics of Retinal Neovascularization in Proliferative Diabetic Retinopathy Imaged by Optical Coherence Tomography Angiography

      Purpose : To characterize the morphology of neovascularization at the disc (NVD) and neovascularization elsewhere (NVE) in treatment-naïve or previously treated proliferative diabetic retinopathy (PDR) patients using optical coherence tomography (OCT) angiography. Methods : En face OCT angiograms of NVD/NVE in 40 eyes of 33 patients with PDR were acquired using RTVue XR Avanti OCT. The morphology of NVD/NVE on OCT angiograms was evaluated, and the activity was determined by biomicroscopy and fluorescein angiography (FA). In 12 eyes that were treated or treatment-naïve, changes in the morphology and vessel area of NVD/NVE before and after panretinal photocoagulation ...

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    5. Radial Peripapillary Capillary Network Visualized Using Wide-Field Montage Optical Coherence Tomography Angiography

      Radial Peripapillary Capillary Network Visualized Using Wide-Field Montage Optical Coherence Tomography Angiography

      Purpose : We quantitatively analyzed the features of a radial peripapillary capillary (RPC) network visualized using wide-field montage optical coherence tomography (OCT) angiography in healthy human eyes. Methods : Twenty eyes of 20 healthy subjects were recruited. En face 3 × 3-mm OCT angiograms of multiple locations in the posterior pole were acquired using the RTVue XR Avanti, and wide-field montage images of the RPC were created. To evaluate the RPC density, the montage images were binarized and skeletonized. The correlation between the RPC density and the retinal nerve fiber layer (RNFL) thickness measured by an OCT circle scan was investigated. Results : The ...

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    6. Evaluation of Retinal Circulation Using Segmental-Scanning Doppler Optical Coherence Tomography in Anesthetized Cats

      Evaluation of Retinal Circulation Using Segmental-Scanning Doppler Optical Coherence Tomography in Anesthetized Cats

      Purpose : To study retinal blood flow (RBF) measurement reproducibility using segmental-scanning Doppler optical coherence tomography (DOCT) in vitro in glass capillaries and in vivo in anesthetized cats. Methods : As a preliminary study, the flow rates of human blood through glass capillaries were changed by using an infusion pump and measured at 13 preset velocities by DOCT. For in vivo measurement, the cats were anesthetized using sevoflurane. The flow in the parent vessel was compared with the sum of the flow values in the two daughter vessels. The RBF was measured using two different instruments: bidirectional laser Doppler velocimetry (LDV) and ...

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    7. En face swept-source optical coherence tomographic analysis of X-linked juvenile retinoschisis

      En face swept-source optical coherence tomographic analysis of X-linked juvenile retinoschisis

      Purpose To clarify the area of retinoschisis by X-linked juvenile retinoschisis (XLRS) using swept-source optical coherence tomography (SS-OCT) en face images. Observations We report two cases of XLRS in the same family. The patients presented with bilateral blurred vision. The posterior segment examination showed a spoked-wheel pattern in the macula. SS-OCT cross-sectional images revealed widespread retinal splitting at the level of the inner nuclear layer bilaterally. We diagnosed XLRS. To evaluate the area of retinoschisis, we obtained en face SS-OCT images, which clearly visualized the area of retinoschisis seen as a sunflower-like structure in the macula. Conclusion and Importance We ...

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    8. RETINAL CAVERNOUS HEMANGIOMA DOCUMENTED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AND CONFOCAL SCANNING LASER OPHTHALMOSCOPE RETRO-MODE IMAGING

      RETINAL CAVERNOUS HEMANGIOMA DOCUMENTED BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AND CONFOCAL SCANNING LASER OPHTHALMOSCOPE RETRO-MODE IMAGING

      Purpose: To report a case of retinal cavernous hemangioma documented by spectral domain optical coherence tomography and retro-mode retinal imaging by confocal scanning laser ophthalmoscope. Methods: Clinical examination, fluorescein angiography, spectral domain optical coherence tomography, and scanning laser ophthalmoscope retro-mode imaging were performed. Results: Fundus examination of the left eye of an asymptomatic 39-year-old woman showed an irregularly elevated dark red lesion with a cluster of various-sized saccular aneurysms. The retinal cavernous hemangioma lesions were in the upper vascular arcade. A late-phase fluorescein angiography image showed a typical finding, known as fluorescence capping, characterized by incomplete perfusion because of plasma-erythrocyte ...

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    9. En-face optical coherence tomography angiography of neovascularization elsewhere in hemicentral retinal vein occlusion

      En-face optical coherence tomography angiography of neovascularization elsewhere in hemicentral retinal vein occlusion

      Purpose: To evaluate how the growth of neovascularization elsewhere (NVE) was delineated in an eye with hemicentral retinal vein occlusion (CRVO) using optical coherence tomography (OCT) angiography. Patients and methods: We examined a 64-year-old man diagnosed with hemi-CRVO. The area around the occluded vein was scanned using a spectral-domain OCT device (RTVue XR Avanti). Blood flow was detected using the split-spectrum amplitude-decorrelation angiography (SSADA) algorithm. Color fundus photography, fluorescein angiography (FA), and OCT angiography examinations were performed at the first visit and at 3 and 6 months postpresentation. Results: At the first visit, FA revealed delayed retinal venous filling and ...

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    10. Enhanced vitreous imaging optical coherence tomography in primary macular holes

      Enhanced vitreous imaging optical coherence tomography in primary macular holes

      The aim of the current pilot study is to investigate the efficacy of a novel enhanced vitreous imaging (EVI) in primary macular holes (MHs) using a spectral-domain optical coherence tomography (SD-OCT). Thirty-four eyes of 32 consecutive patients with a MH were examined in one time cross-sectional study. The vitreomacular interface was assessed using SD-OCT with conventional and EVI technique. Twenty-three of the 34 eyes did not show a Weiss ring, and in 22 of those, we observed a MH with an open roof or operculum and a detached posterior vitreous cortex with conventional vitreous imaging. Using EVI-OCT, we visualized the ...

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    11. Optical Coherence Tomography Angiography in Diabetic Retinopathy: A Prospective Pilot Study

      Optical Coherence Tomography Angiography in Diabetic Retinopathy: A Prospective Pilot Study

      Purpose To evaluate how optical coherence tomography (OCT) angiography depicts clinical fundus findings in patients with diabetic retinopathy (DR). Design Prospective study evaluating imaging technology. Methods Forty-seven eyes of 25 patients with DR were scanned using a high-speed 840-nm wavelength spectral-domain optical coherence tomography instrument (RTVue XR Avanti, Optovue, Inc., Fremont, CA). Blood flow was detected using the split-spectrum amplitude-decorrelation angiography algorithm. Fluorescein angiography (FA) images were also obtained in all eyes and the ability to visualize microaneurysms, retinal non-perfused areas, and neovascularization was compared with that of the en-face OCT angiograms. Results In 42 eyes, microaneurysms detected by FA ...

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    12. Patency of small laser iridotomy evaluated using anterior-segment optical coherence tomography

      Patency of small laser iridotomy evaluated using anterior-segment optical coherence tomography

      We report the case of a patient with recurrent acute angle-closure glaucoma who had undergone a previous laser iridotomy. Because the initial iridotomy was small, patency could not be determined by slit-lamp examination. Therefore, anterior-segment optical coherence tomography was used to evaluate the patency. Cross-sectional images showed the presence of a membrane with an anterior bowing configuration at the base of the iridotomy, suggesting that recurrent pupillary block was the causative mechanism. A repeat laser iridotomy was performed, with a resultant decrease in the intraocular pressure and widening of the anterior chamber angle. Anterior-segment optical coherence tomography may be helpful ...

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    13. Idiopathic Full-Thickness Macular Holes and the Vitreomacular Interface: A High-Resolution Spectral-Domain Optical Coherence Tomography Study

      Idiopathic Full-Thickness Macular Holes and the Vitreomacular Interface: A High-Resolution Spectral-Domain Optical Coherence Tomography Study

      Purpose To analyze the vitreomacular interface in idiopathic full-thickness macular holes (MHs) using spectral-domain optical coherence tomography. Design Prospective cross-sectional case series. Methods Ninety-one eyes of 86 consecutive patients with a MH were examined by spectral-domain optical coherence tomography. The vitreomacular interface was assessed and the presence or absence of an operculum was analyzed. Results Fifty-two eyes had a stage 2 MH, 12 eyes a stage 3 MH, and 27 eyes a stage 4 MH. No posterior hyaloid membrane was detected in any eyes with a stage 4 MH. In 35 (54.7%) of the 64 eyes with an MH ...

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    14. Central Corneal Thickness Measurements With Fourier-Domain Optical Coherence Tomography Versus Ultrasonic Pachymetry and Rotating Scheimpflug Camera

      Central Corneal Thickness Measurements With Fourier-Domain Optical Coherence Tomography Versus Ultrasonic Pachymetry and Rotating Scheimpflug Camera
      Purpose: To compare the accuracy and repeatability of Fourier-domain optical coherence tomography (FD-OCT) with ultrasonic pachymetry (USP) and a rotating Scheimpflug camera for measuring the central corneal thickness (CCT). Methods: The CCT was measured in 30 subjects (30 normal corneas) by the same examiner using RTVue-100 FD-OCT with an anterior segment adaptor, Pentacam rotating Scheimpflug camera, and SP-2000 USP. Two examiners obtained one FD-OCT measurement from 10 eyes of 5 subjects to assess interexaminer reproducibility. Results: The mean CCT (±SD) measured by FD-OCT, USP, and the Pentacam were 530 ± 33, 544 ± 34, and 552 ± 35 μm, respectively. Significant correlations were ...
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    15. STAGE 1-A MACULAR HOLE: A Prospective Spectral-Domain Optical Coherence Tomography Study

      STAGE 1-A MACULAR HOLE: A Prospective Spectral-Domain Optical Coherence Tomography Study
      Purpose: To determine the anatomical morphology of Stage 1-A impending macular holes characterized by a yellow spot using spectral-domain optical coherence tomography to study the fellow eyes of patients diagnosed with a full-thickness macular hole or eyes with a typical yellow spot with metamorphopsia. Methods: Prospective observational case series of 45 patients with a full-thickness macular hole or a foveolar yellow spot with metamorphopsia. Visual acuity assessment, biomicroscopic examination, and spectral-domain optical coherence tomography were performed. Clinical ophthalmologic examinations were repeated, including spectral-domain optical coherence tomography, in the eyes with a foveolar yellow spot at 1-month interval. Results: We examined ...
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    16. Foveal Anatomic Changes in a Progressing Stage 1 Macular Hole Documented by Spectral-Domain Optical Coherence Tomography

      Objective: To report the case of a stage 1 macular hole and the sequential intrafoveal changes with spectral-domain optical coherence tomography (SD-OCT).Design: Single, observational case report.Participant: A 51-year-old woman with a stage 1A macular hole that progressed to a stage 2 macular hole.Methods: Clinical ophthalmologic examinations were repeated, including SD-OCT, during follow-up at intervals of several weeks.Main Outcome Measures: Sequential intrafoveal tomographic alterations in a patient with a stage 1 macular hole. Foveal splits in the inner retina progressed to an enlarged pseudocyst that disrupted the outer retinal layer (ORL) resulting from the vitreous traction associated ...
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    17. Morphological study of acute zonal occult outer retinopathy (azoor) by multiplanar optical coherence tomography

      Purpose: We set out to determine whether morphological retinal changes occur in patients with acute zonal occult outer retinopathy (AZOOR).Methods: Five patients diagnosed with AZOOR were studied. They included two men and three women, with an age range of 23[minus]51 years. Symptoms and findings were retrospectively and prospectively collected. The three-dimensional multiplanar optical coherence tomography (OCT) Ophthalmoscope® was used to examine the morphology of the retina in patients who were examined between April 2000 to December 2004. Standardized full-field electroretinograms (ERGs) and multifocal ERGs (mfERGs) were recorded.Results: All the patients reported an acute onset of visual ...
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    1-18 of 18
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    STAGE 1-A MACULAR HOLE: A Prospective Spectral-Domain Optical Coherence Tomography Study Central Corneal Thickness Measurements With Fourier-Domain Optical Coherence Tomography Versus Ultrasonic Pachymetry and Rotating Scheimpflug Camera Idiopathic Full-Thickness Macular Holes and the Vitreomacular Interface: A High-Resolution Spectral-Domain Optical Coherence Tomography Study Hypertensive choroidopathy with eclampsia viewed on spectral-domain optical coherence tomography Patency of small laser iridotomy evaluated using anterior-segment optical coherence tomography Optical Coherence Tomography Angiography in Diabetic Retinopathy: A Prospective Pilot Study Enhanced vitreous imaging optical coherence tomography in primary macular holes En face swept-source optical coherence tomographic analysis of X-linked juvenile retinoschisis Choroidal Vascularity Index Using Swept-Source and Spectral-Domain Optical Coherence Tomography: A Comparative Study Evaluation of equine corneal disease using spectral domain optical coherence tomography (SD‐OCT) Attention to Lesion: Lesion-Aware Convolutional Neural Network for Retinal Optical Coherence Tomography Image Classification Telecentric broadband objective lenses for optical coherence tomography