1. Articles from Gioel Gabrio Secco

    1-9 of 9
    1. Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds

      Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds

      Background The effect of optical coherence tomography (OCT) guidance on the implantation strategy during all phases of percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVSs) in a real-world scenario has been poorly investigated. Methods Consecutive patients undergoing BVS implantation at our institution were included in this registry. Frequency-domain OCT pullbacks were performed at the operator's discretion during all phases of BVS implantation procedures to optimize preparation of lesions, confirm BVS size, and optimize expansion and apposition of scaffolds. Results Between September 2012 and July 2015, 203 BVSs were implanted in 101 consecutive patients at our institution (2.01 ...

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    2. Is high pressure postdilation safe in bioresorbable vascular scaffolds? Optical coherence tomography observations after noncompliant balloons inflated at more than 24 atmospheres

      Is high pressure postdilation safe in bioresorbable vascular scaffolds? Optical coherence tomography observations after noncompliant balloons inflated at more than 24 atmospheres

      Objectives Optical coherence tomography (OCT) was used to investigate integrity and expansion of bioresorbable drug-eluting scaffolds (BVS) after high-pressure postdilation (HPPD). Background Because of concerns about the risk of BVS damage, postdilation was not recommended and applied in the existing randomized studies and most registries. Recent real world data suggest incomplete BVS expansion cause higher rates of thrombosis. In vivo confirmation of the safety of high pressure postdilation is of paramount importance. Methods Data from final OCT examination of consecutive implanted BVS, postdilated with noncompliant (NC) balloons at pressure ≥24 atm were analyzed. The following stent performance indices were assessed ...

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    3. Optical Coherence Tomography during carotid artery stenting: A new niche application?

      Optical Coherence Tomography during carotid artery stenting: A new niche application?

      In the past decades angiography has been the keystone to assess vascular anatomy, leading to the development of largely applied percutaneous revascularisation techniques. However, angiography can only provide a limited analysis of lumen profile without the possibility to disclose vessel wall characteristics and composition of atherosclerotic lesions. Intravascular ultrasound (IVUS), introduced in the early ‘90ies, followed more then a decade after by optical coherence tomography (OCT) provide information about intravascular anatomy that far exceeds the level of detail obtained from conventional angiography.

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    4. Intracoronary Optical Coherence Tomography: Experience and Indications for Clinical Use

      Intracoronary Optical Coherence Tomography: Experience and Indications for Clinical Use

      Optical coherence tomography (OCT) is a light based technology that provides very high spatial resolution images. OCT has been initially employed as a research tool to investigate plaque morphology and stent strut coverage. The introduction of frequency domain OCT, allowing fast image acquisition during a prolonged contrast injection via the guiding catheter, has made OCT applicable for guidance of coronary interventions. In this manuscript the various applications of OCT are reviewed, from assessment of plaque vulnerability and severity to characteristics of unstable lesions and thrombus burden to stent optimization and evaluation of late results

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    5. Safety and efficacy of saline infusion for optical coherence tomography evaluation of vascular lesion induced by renal nerve ablation

      Safety and efficacy of saline infusion for optical coherence tomography evaluation of vascular lesion induced by renal nerve ablation

      Renal nerve ablation (RNA) using radiofrequency (RF) catheter-based has been recently proposed for the treatment of severe drug-resistant hypertension . Despite preliminary animal studies showing the safety and efficacy of this procedure, recent in-human studies highlighted the possibility of vascular lesions following RF emission . Templin et al. recently evaluated 32 renal arteries before and after the RNA-procedure using optical coherence tomography (OCT) .

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    6. Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons

      Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons

      Aims: The treatment of in-stent restenosis (ISR) remains a challenge with poor immediate results and higher restenosis rate than in de novo lesions. We propose, based on a consecutive series of patients treated with cutting balloon, a strategy of aggressive device selection based on the results of serial FD-OCT assessment.

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    7. Long-term tissue coverage of a biodegradable polylactide polymer–coated biolimus-eluting stent: Comparative sequential assessment with optical coherence tomography until complete resorption of the polymer

      Long-term tissue coverage of a biodegradable polylactide polymer–coated biolimus-eluting stent: Comparative sequential assessment with optical coherence tomography until complete resorption of the polymer

      Background: Biolimus-eluting stents (BESs) with a biodegradable polymer in abluminal coating achieve more complete coverage at 9 months compared with sirolimus-eluting stents (SESs) with a durable polymer, as assessed by optical coherence tomography (OCT). Whether this advantage persists or augments after complete resorption of the polymer (>12 months) is unknown.Methods: The LEADERS trial compared the performance of BES with that of SES. Patients were randomly allocated to a sequential angiographic follow-up, including OCT in selected sites, at 9 and 24 months. Struts coverage was compared using Bayesian hierarchical models as the primary outcome for the OCT substudy.Results: Fifty-six ...

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    1-9 of 9
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    Long-term tissue coverage of a biodegradable polylactide polymer–coated biolimus-eluting stent: Comparative sequential assessment with optical coherence tomography until complete resorption of the polymer Optical coherence tomography for guidance of treatment of in-stent restenosis with cutting balloons Safety and efficacy of saline infusion for optical coherence tomography evaluation of vascular lesion induced by renal nerve ablation Intracoronary Optical Coherence Tomography: Experience and Indications for Clinical Use Saline vs contrast infusion during optical coherence tomography imaging of peripheral percutaneous intervention Optical Coherence Tomography Guidance during Peripheral Vascular Intervention Optical Coherence Tomography during carotid artery stenting: A new niche application? Is high pressure postdilation safe in bioresorbable vascular scaffolds? Optical coherence tomography observations after noncompliant balloons inflated at more than 24 atmospheres Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds Comparative study between intravitreal ranibizumab and triamcinolone treatment of diabetic macular edema as regard to optical coherence tomography changes and visual acuity What’s New in Optical Coherence Tomography Angiography for Glaucoma (Book Chapter) Looking into the Future: Optical Coherence Tomography for the Assessment of Cardiac Allograft Vasculopathy