1. Articles from Enock Jonathan

    1-4 of 4
    1. In vivo imaging of the microcirculation of the volar forearm using correlation mapping optical coherence tomography (cmOCT)

      In vivo imaging of the microcirculation of the volar forearm using correlation mapping optical coherence tomography (cmOCT)
      Correlation mapping optical coherence tomography (cmOCT) is a recently proposed technique that extends the capabilities of OCT to enable mapping of vasculature networks. The technique is achieved as a processing step on OCT intensity images that does not require any modification to existing OCT hardware. In this paper we apply the cmOCT processing technique to in vivo human imaging of the volar forearm. We illustrate that cmOCT can produce maps of the microcirculation that clearly follow the accepted anatomical structure. We demonstrate that the technique can extract parameters such as capillary density and vessel diameter. These parameters are key clinical ...
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    2. In-vivo assessment of cleavage line orientation in human skin using optical coherence tomography

      In-vivo assessment of cleavage line orientation in human skin using optical coherence tomography
      Collagen and elastin fibers are generally arranged in parallel bundles within the dermis. These bundles are oriented such that they can most efficiently resist the stress and strain that normally occurs on the skin during movement. The pattern of these fiber bundles establishes the lines of cleavage of the skin. Knowledge of the orientation of these is of key importance for surgical procedures. When incisions are cut parallel to the cleavage line orientation the incision will heal better and produce less scaring. In this work we report a novel application of Optical coherence tomography for the determination of cleavage line ...
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    3. Correlation mapping method for generating microcirculation morphology from optical coherence tomography (OCT) intensity images

      Correlation mapping method for generating microcirculation morphology from optical coherence tomography (OCT) intensity images
      Standard optical coherence tomography (OCT) in combination with software tools can be harnessed to generate vascular maps in vivo. In this study we have successfully combined a software algorithm based on correlation statistic to reveal microcirculation morphology on OCT intensity images of a mouse brain in vivo captured trans-cranially and through a cranial window. We were able to estimate vessel geometry at bifurcation as well as along vessel segments down-to mean diameters of about 24 μm. Our technique has potential applications in cardiovascular-related parameter measurements such as volumetric flow as well as in assessing vascular density of normal and diseased ...
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    4. In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography

      In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography
      The use of microneedles as a method of circumventing the barrier properties of the stratum corneum is receiving much attention. Although skin disruption technologies and subsequent transdermal diffusion rates are being extensively studied, no accurate data on depth and closure kinetics of microneedle-induced skin pores are available, primarily due to the cumbersome techniques currently required for skin analysis. We report on the first use of optical coherence tomography technology to image microneedle penetration in real time and in vivo. We show that optical coherence tomography (OCT) can be used to painlessly measure stratum corneum and epidermis thickness, as well as ...
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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Limerick
    2. (4 articles) National University of Ireland, Galway
    3. (4 articles) Enock Jonathan
    4. (4 articles) Martin J. Leahy
    5. (1 articles) University College Cork
    6. (1 articles) University of Groningen
    7. (1 articles) NinePoint Medical
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    In-vivo dynamic characterization of microneedle skin penetration using optical coherence tomography Correlation mapping method for generating microcirculation morphology from optical coherence tomography (OCT) intensity images In-vivo assessment of cleavage line orientation in human skin using optical coherence tomography In vivo imaging of the microcirculation of the volar forearm using correlation mapping optical coherence tomography (cmOCT) Long-Term Arterial Remodeling After Bioresorbable Scaffold Implantation 4-Year Follow-up of Quantitative Coronary Angiography, Histology and Optical Coherence Tomography Visualization of Bacterial Colonization and Cellular Layers in a Gut-on-a-Chip System Using Optical Coherence Tomography Optical Coherence Tomography Measurements as Potential Imaging Biomarkers for Parkinson's Disease: A Systematic Review and Meta-analysis Use of ultra-wide field retinal imaging and optical coherence tomography angiography in the diagnosis of incomplete Susac syndrome NinePoint Medical, Inc. filed a voluntary petition for relief under Chapter 11 of the United States Bankruptcy Code Repeatability and agreement of total corneal and sublayer pachymetry with two different algorithms of fourier-domain optical coherence tomography in myopic and post photorefractive keratectomy eyes Monitoring Response to Platelet-Rich Plasma in Patients with Alopecia Areata with Optical Coherence Tomography: A Case Series NONPERFUSION AREA QUANTIFICATION IN BRANCH RETINAL VEIN OCCLUSION: A WIDEFIELD OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY STUDY