1. Articles from Mark S. Blumenkranz

    1-5 of 5
    1. Apparatus for patterned plasma-mediated laser ophthalmic surgery

      Apparatus for patterned plasma-mediated laser ophthalmic surgery

      A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on ...

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      Mentions: OptiMedica
    2. Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy

      Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy
      Background: The purpose of this study was to characterize central macular thickness and retinal volume following intravitreal injections using time domain and spectral domain optical coherence tomography (TD-OCT and SD-OCT, respectively). Methods: Nine patients with macular edema secondary to diabetes or retinal vein occlusion treated with intravitreal triamcinolone 4.0 mg and/or bevacizumab 1.25 mg were enrolled. Central macular thickness and volume was measured by SD-OCT and TD-OCT scan at baseline, and 1, 3, 6, 24, 48 hours, and 1 week postinjection. Results: Equations were derived to describe central macular thickness and volume reduction in the hours following ...
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    3. Femtosecond laser capsulotomy (optical coherence tomography guided)

      Femtosecond laser capsulotomy (optical coherence tomography guided)
      Purpose: To evaluate a femtosecond laser system to create the capsulotomy.Setting: Porcine and cadaver eye studies were performed at OptiMedica Corp., Santa Clara, California, USA; the human trial was performed at the Centro Laser, Santo Domingo, Dominican Republic.Design: Experimental and clinical study.Methods: Capsulotomies performed by an optical coherence tomography–guided femtosecond laser were evaluated in porcine and human cadaver eyes. Subsequently, the procedure was performed in 39 patients as part of a prospective randomized study of femtosecond laser-assisted cataract surgery. The accuracy of the capsulotomy size, shape, and centration were quantified and capsulotomy strength was assessed in ...
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    4. Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography

      Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography
      Abstract About one-third of people in the developed world will undergo cataract surgery in their lifetime. Although marked improvements in surgical technique have occurred since the development of the current approach to lens replacement in the late 1960s and early 1970s, some critical steps of the procedure can still only be executed with limited precision. Current practice requires manual formation of an opening in the anterior lens capsule, fragmentation and evacuation of the lens tissue with an ultrasound probe, and implantation of a plastic intraocular lens into the remaining capsular bag. The size, shape, and position of the anterior capsular ...
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    5. Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema

      Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema
      Purpose: The purpose of this study was to evaluate the correlation between best-corrected visual acuity (BCVA) and macular thickness in patients with persistent macular edema treated with a dexamethasone intravitreal drug delivery system (dexamethasone DDS). Methods: In a randomized, multicenter, controlled, parallel-group, dose-ranging study, patients with macular edema lasting at least 90 days despite treatment were randomized to observation or treatment with 350- or 700-μg dexamethasone DDS. Macular thickness was assessed in 80 patients using optical coherence tomography. Best-corrected visual acuity was measured using Early Treatment Diabetic Retinopathy Study methodology. Results: At baseline, macular thickness was significantly inversely correlated with ...
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    1-5 of 5
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    1. (3 articles) OptiMedica
    2. (2 articles) Stanford University
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    5. (2 articles) National Institutes of Health
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    Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography Femtosecond laser capsulotomy (optical coherence tomography guided) Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy Apparatus for patterned plasma-mediated laser ophthalmic surgery Optical coherence tomography angiography of stimulus evoked hemodynamic responses in individual retinal layers Ultrathin forward-imaging short multimode fiber probe for full-field optical coherence microscopy Choroidal Vascularity Index in Vogt-Koyanagi-Harada Disease: An EDI-OCT Derived Tool for Monitoring Disease Progression Volumetric Image Classification using Homogeneous Decomposition and Dictionary Learning: A Study Using Retinal Optical Coherence Tomography for Detecting Age-related Macular Degeneration Post-Mortem Corneal Thickness Measurements with a Portable Optical Coherence Tomography System: a Reliability Study Retinal nerve fiber and optic disc morphology using spectral-domain optical coherence tomography in scleroderma patients Optical coherence tomography imaging of optic disc cavernous haemangioma