1. Articles from Mark S. Blumenkranz

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    1. Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy

      Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy
      Background: The purpose of this study was to characterize central macular thickness and retinal volume following intravitreal injections using time domain and spectral domain optical coherence tomography (TD-OCT and SD-OCT, respectively). Methods: Nine patients with macular edema secondary to diabetes or retinal vein occlusion treated with intravitreal triamcinolone 4.0 mg and/or bevacizumab 1.25 mg were enrolled. Central macular thickness and volume was measured by SD-OCT and TD-OCT scan at baseline, and 1, 3, 6, 24, 48 hours, and 1 week postinjection. Results: Equations were derived to describe central macular thickness and volume reduction in the hours following ...
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    2. Femtosecond laser capsulotomy (optical coherence tomography guided)

      Femtosecond laser capsulotomy (optical coherence tomography guided)
      Purpose: To evaluate a femtosecond laser system to create the capsulotomy.Setting: Porcine and cadaver eye studies were performed at OptiMedica Corp., Santa Clara, California, USA; the human trial was performed at the Centro Laser, Santo Domingo, Dominican Republic.Design: Experimental and clinical study.Methods: Capsulotomies performed by an optical coherence tomography–guided femtosecond laser were evaluated in porcine and human cadaver eyes. Subsequently, the procedure was performed in 39 patients as part of a prospective randomized study of femtosecond laser-assisted cataract surgery. The accuracy of the capsulotomy size, shape, and centration were quantified and capsulotomy strength was assessed in ...
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    3. Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography

      Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography
      Abstract About one-third of people in the developed world will undergo cataract surgery in their lifetime. Although marked improvements in surgical technique have occurred since the development of the current approach to lens replacement in the late 1960s and early 1970s, some critical steps of the procedure can still only be executed with limited precision. Current practice requires manual formation of an opening in the anterior lens capsule, fragmentation and evacuation of the lens tissue with an ultrasound probe, and implantation of a plastic intraocular lens into the remaining capsular bag. The size, shape, and position of the anterior capsular ...
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    4. Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema

      Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema
      Purpose: The purpose of this study was to evaluate the correlation between best-corrected visual acuity (BCVA) and macular thickness in patients with persistent macular edema treated with a dexamethasone intravitreal drug delivery system (dexamethasone DDS). Methods: In a randomized, multicenter, controlled, parallel-group, dose-ranging study, patients with macular edema lasting at least 90 days despite treatment were randomized to observation or treatment with 350- or 700-μg dexamethasone DDS. Macular thickness was assessed in 80 patients using optical coherence tomography. Best-corrected visual acuity was measured using Early Treatment Diabetic Retinopathy Study methodology. Results: At baseline, macular thickness was significantly inversely correlated with ...
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    1-4 of 4
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  2. Topics in the News

    1. (2 articles) Stanford University
    2. (2 articles) Neil J. Friedman
    3. (2 articles) William W. Culbertson
    4. (2 articles) OptiMedica
    5. (1 articles) University of Miami
    6. (1 articles) Daniel Palanker
    7. (1 articles) Carl Zeiss Meditec
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    Correlation of Visual Acuity and Macular Thickness Measured By Optical Coherence Tomography in Patients With Persistent Macular Edema Femtosecond Laser–Assisted Cataract Surgery with Integrated Optical Coherence Tomography Femtosecond laser capsulotomy (optical coherence tomography guided) Kinetics of central macular thickness reduction in patients with macular edema after intravitreal drug therapy Re: Garcia-Martin et al.: Retinal layer segmentation in patients with multiple sclerosis using spectral domain optical coherence tomography Difference of GCIPL Thickness of Diabetes and Normal Eyes in Spectral Domain OCT Iterative Nonlocal Means Method for Despeckling Optical Coherence Tomography Images Foveal Shape According to Age and Gender Using Spectral Domain Optical Coherence Tomography Optical Coherence Tomography Conference at the University of Manchester December 3rd 2014 In Vivo High-Definition Optical Coherence Tomography: A Bedside Diagnostic Aid for Morphea Change in Drusen Area Over Time Compared Using Spectral Domain Optical Coherence Tomagraphy and Color Fundus Imaging Variability and Repeatability of Quantitative, Fourier Domain-OCT Doppler Blood Flow in Young and Elderly Healthy Subjects