1. Articles from A. Karanasos

    1-4 of 4
    1. Visualization of extensive intraplaque neovascularization by optical coherence tomography

      Visualization of extensive intraplaque neovascularization by optical coherence tomography

      Inflammation plays a key role in pathogenesis and progression of atherosclerosis (1) . Advent of novel intravascular imaging tools such as Optical Coherence Tomography (OCT) has led to visualization of coronary atherosclerotic plaque characteristics in vivo that were previously seen only on histology. Herein we discuss a case of extensive neovascularization, a feature that imparts vulnerability to atherosclerotic plaque in the coronary artery, as seen by two- and three-dimensional OCT images. A 63-year-old female with history of diabetes mellitus and hypertension presented with troponin-positive chest pain. She underwent coronary angiography followed by drug-eluting stent implantation to the mid segment of right ...

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    2. OCT demonstrating neoatherosclerosis as part of the continuous process of coronary artery disease

      OCT demonstrating neoatherosclerosis as part of the continuous process of coronary artery disease

      Although the advent of drug-eluting stents has reduced the rates of target vessel revascularization, there are observations of ongoing stent failure occurring very late after stent implantation and presenting as very late restenosis or as very late stent thrombosis. The de novo development of atherosclerosis within the neointimal region, called neoatherosclerosis, has been identified as one of the pathomechanisms of these observed late stent failures. The mechanisms of neoatherosclerosis development and its association with stent failure are currently the subject of intensive research. Optical coherence tomography (OCT) is an invasive imaging modality that allows us to visualize the micromorphology of ...

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    3. The impact of Fourier-Domain optical coherence tomography catheter induced motion artefacts on quantitative measurements of a PLLA-based bioresorbable scaffold

      The impact of Fourier-Domain optical coherence tomography catheter induced motion artefacts on quantitative measurements of a PLLA-based bioresorbable scaffold

      Intracoronary Fourier-Domain optical coherence tomography (FD-OCT) enables imaging of the coronary artery within 2-4 seconds, a so far unparalleled speed. Despite such fast data acquisition, cardiac and respiratory motion can cause artefacts due to longitudinal displacement of the catheter within the artery. We studied the influence of longitudinal FD-OCT catheter displacement on serial global lumen and scaffold area measurements in coronary arteries of swine that received PLLA-based bioresorbable scaffolds. In 10 swine, 20 scaffolds (18 × 3.0 mm) were randomly implanted in two epicardial coronary arteries. Serial FD-OCT imaging was performed immediately after implantation (T1) and at 3 (T2) and ...

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    4. Multiple plaque morphologies assessed by optical coherence tomography in a patient with acute coronary syndrome

      Multiple plaque morphologies assessed by optical coherence tomography in a patient with acute coronary syndrome

      A 64-year-old male patient presented at the emergency department with chest pain. ST-segment depression (1 mm) was present in leads V4–V6, and cardiac troponin was elevated (10.4 ng/ml). He was treated medically, and he did not have any chest pain thereafter. We performed coronary angiography 60 h later, which revealed a proximal lesion in the left circumflex artery with a

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    1-4 of 4
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  2. Topics in the News

    1. (3 articles) Erasmus University
    2. (3 articles) Antonios Karanasos
    3. (3 articles) Evelyn Regar
    4. (1 articles) University College London
    5. (1 articles) Geert Springeling
    6. (1 articles) Heleen M. M. Van Beusekom
    7. (1 articles) Jurgen M. Ligthart
    8. (1 articles) Hector M. Garcia-Garcia
    9. (1 articles) Nico Bruining
    10. (1 articles) Karen T. Witberg
    11. (1 articles) South China Normal University
    12. (1 articles) Indiana University
    13. (1 articles) Donald T. Miller
    14. (1 articles) Boston Scientific
    15. (1 articles) Abbot
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    Multiple plaque morphologies assessed by optical coherence tomography in a patient with acute coronary syndrome The impact of Fourier-Domain optical coherence tomography catheter induced motion artefacts on quantitative measurements of a PLLA-based bioresorbable scaffold OCT demonstrating neoatherosclerosis as part of the continuous process of coronary artery disease Visualization of extensive intraplaque neovascularization by optical coherence tomography Optical coherence tomography angiography (OCTA) findings in Serpiginous Choroiditis Changes in retinal layer thickness with maturation in the dog: an in vivo spectral domain - optical coherence tomography imaging study Optical coherence tomography angiography analysis of fabry disease An unsupervised hierarchical approach for automatic intra‐retinal cyst segmentation in spectral‐domain optical coherence tomography images Towards quantitative assessment of burn based on photoacoustic and optical coherence tomography Cellular Scale Imaging of Transparent Retinal Structures and Processes Using Adaptive Optics Optical Coherence Tomography Optical Coherence Tomography Imaging in Acute Myocardial Infarction: Calcified Nodule as a Culprit Lesion Study of low-peak-power highly coherent broadband supercontinuum generation through a dispersion-engineered Si-rich silicon nitride waveguide