1. Articles from masafumi ota

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    1. Association Between Fluorescein Leakage and Optical Coherence Tomographic Characteristics of Microaneurysms in Diabetic Retinopathy

      Association Between Fluorescein Leakage and Optical Coherence Tomographic Characteristics of Microaneurysms in Diabetic Retinopathy

      Purpose: To evaluate the characteristics of microaneurysms seen on color fundus photography, fluorescein angiography, and spectral-domain optical coherence tomography in diabetic retinopathy. Methods: One hundred and thirty-two consecutive eyes of 92 patients with diabetic retinopathy were reviewed retrospectively. The characteristics of microaneurysms, including capsular structure (ring sign), hyperreflective spots in the lumen, the retinal layers in which they are located, and adjacent cystoid spaces, were documented on spectral-domain optical coherence tomography as sectional images. Their appearance on fundus photographs and focal fluorescein leakage were recorded. The association among these characteristics was evaluated. Results: Eighty-eight of 118 microaneurysms (74.6%) with ...

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    2. Characteristics of Optical Coherence Tomographic Hyperreflective Foci in Retinal Vein Occlusion

      Characteristics of Optical Coherence Tomographic Hyperreflective Foci in Retinal Vein Occlusion
      Purpose: To evaluate the hyperreflective foci in branch retinal vein occlusion and central retinal vein occlusion depicted by spectral-domain optical coherence tomography (OCT). Methods: Consecutive series of 73 eyes of 73 patients with retinal vein occlusion (58 branch retinal vein occlusion and 15 central retinal vein occlusion) who had Spectralis OCT images obtained were retrospectively reviewed, comparing color fundus photographs and fluorescein angiography. Results: Hyperreflective foci were detected in 54 eyes (74.0%) by spectral-domain OCT, and hard exudates were detected in 17 eyes (23.3%) by color fundus photography. Hard exudates on the color photographs corresponded to the confluence ...
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    3. Optical Coherence Tomographic Characteristics of Microaneurysms in Diabetic Retinopathy

      Optical Coherence Tomographic Characteristics of Microaneurysms in Diabetic Retinopathy
      Purpose: To characterize microaneurysms in diabetic retinopathy (DR) depicted by spectral-domain optical coherence tomography (SD-OCT).Design: Retrospective, observational case series.Methods: We surveyed a consecutive series of 76 eyes from 60 patients with DR (22 mild nonproliferative diabetic retinopathy [NPDR]; 43 moderate NPDR; 9 severe NPDR; 2 proliferative diabetic retinopathy [PDR]) who underwent Spectralis OCT, fluorescein angiography (FA), and color fundus photography on the same day. The microaneurysms on OCT were oval and well demarcated at the points where those on color fundus photographs and FA were delineated. The characteristics of microaneurysms were evaluated.Results: Based on the status of ...
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    4. Optical Coherence Tomographic Evaluation of Foveal Hard Exudates in Patients with Diabetic Maculopathy Accompanying Macular Detachment

      Optical Coherence Tomographic Evaluation of Foveal Hard Exudates in Patients with Diabetic Maculopathy Accompanying Macular Detachment
      Objective:: To study morphologic changes of serous retinal detachment (SRD) and hyperreflective dots, which have been reported to be precursors of hard exudates, detectable in SRD using optical coherence tomography (OCT) to assess whether or not the OCT findings are correlated with the subfoveal deposition of hard exudates in patients with diabetic macular edema (DME) accompanied by SRD.Design:: Retrospective chart review.Participants:: Twenty-eight eyes of 19 patients with DME accompanied by SRD.Methods:: We imaged SRD and the hyperreflective dots in SRD using spectral domain OCT (SD-OCT). The number and distribution of the hyperreflective dots in SRD were evaluated ...
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    5. Retinal Structural Changes Associated With Retinal Arterial Macroaneurysm Examined With Optical Coherence Tomography.

      Retinal arterial macroaneurysm can cause hemorrhagic and/or exudative complications. Eyes with minimal hemorrhage from the aneurysm often showed an extensive exudative change that extended to the fovea. In these eyes, retinal edema was seen predominantly in the outer nuclear layer, accompanying a focal serous retinal detachment beneath the fovea.Page: 782DOI: 10.1097/IAE.0b013e3181a2f26aAuthors: TSUJIKAWA, AKITAKA MD; SAKAMOTO, ATSUSHI MD; OTA, MASAFUMI MD; OH, HIDEYASU MD; MIYAMOTO, KAZUAKI MD; KITA, MIHORI MD; YOSHIMURA, NAGAHISA MD
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    6. Evaluation of potential visual acuity in eyes with macular oedema secondary to retinal vein occlusion

      Purpose: To evaluate the potential visual acuity (VA) of eyes with macular oedema (MO) associated with retinal vein occlusion (RVO). Methods: Thirty-one eyes of 31 patients with MO associated with RVO were examined and then treated with an intravitreal injection of bevacizumab. Of these 31 eyes, 22 showed complete resolution of the MO at 1 month after treatment, at which time potential VA was determined; 12 eyes had good function and 10 had poor function at this time. Optical coherence tomography was used to detect the junctions between inner and outer segments of the photoreceptors (IS/OS) as a hallmark ...
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    7. Association between Foveal Photoreceptor Integrity and Visual Outcome in Neovascular Age-related Macular Degeneration

      Purpose: To evaluate the correlation between visual outcome and foveal photoreceptor integrity after successful treatment of eyes with neovascular age-related macular degeneration (AMD).Design: Retrospective chart review.Methods: We retrospectively studied the medical records of 51 eyes of 51 patients with neovascular AMD who were treated successfully with photodynamic therapy (PDT). All eyes were followed-up for more than 24 months after the initial treatment. Using spectral-domain optical coherence tomography, the status of the inner segment and outer segment (IS/OS) photoreceptor junction was assessed as a hallmark of the integrity of the foveal photoreceptor layer.Results: At the final visit ...

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    8. Foveal Photoreceptor Layer in Eyes with Persistent Cystoid Macular Edema Associated with Branch Retinal Vein Occlusion

      A prototype high-speed OCT system was fabricated for patient examinations based on Fourier domain OCT. The system had a sensitivity of 98 dB, a tissue axial resolution of 4.3 μm, and an acquisition rate of approximately 18 700 axial scans per second. Three-dimensional imaging was performed based on a raster-scan protocol. Anatomic features of CSC distinguished by 3-D OCT. A line corresponding to backreflection from the external limiting membrane (ELM) was visible in images from eyes with all sta
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    1-8 of 8
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