1. Articles from fumi gomi

    1-12 of 12
    1. Novel Method for Evaluation of Ocular Torsion Angle by Optical Coherence Tomography

      Novel Method for Evaluation of Ocular Torsion Angle by Optical Coherence Tomography

      Purpose : The Glaucoma Module Premium Edition (GMPE) software for the SPECTRALIS optical coherence tomography (OCT) is able to automatically track the anatomic centers of both the fovea and the optic disc. We investigated the efficacy of the OCT in measuring the ocular torsion angle before and after strabismus surgery. Methods : Between June 2017 and December 2018, 40 patients with cyclodeviation who had undergone strabismus surgery at Hyogo College of Medicine were enrolled. Ocular torsion angle measurements, including OCT and nonmydriatic fundus camera for objective measurements and synoptophore for subjective measurements, were performed before surgery and 1 day after surgery. Results ...

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    2. Indocyanine Green Dye Filling Time for Polypoidal Lesions in Polypoidal Choroidal Vasculopathy Affects the Visibility of the Lesions on OCT Angiography

      Indocyanine Green Dye Filling Time for Polypoidal Lesions in Polypoidal Choroidal Vasculopathy Affects the Visibility of the Lesions on OCT Angiography

      Purpose To elucidate the factors that affect the visibility of polypoidal lesions on OCT angiography (OCTA) based on indocyanine green angiography (ICGA) findings in eyes with polypoidal choroidal vasculopathy (PCV). Design Retrospective, consecutive case series. Participants Thirty-one eyes of 31 patients with PCV diagnosed on ICGA. Methods We compared the numbers of polyps visible on ICGA and on OCTA. The following time points and durations were determined: first appearance of dye in the choroidal arteries, first appearance of dye within a polyp, and the time it took the dye to fill entire lesions. Then we compared visible and invisible polyps ...

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    3. Analysis of choroidal folds in acute Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography

      Analysis of choroidal folds in acute Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography

      Purpose To characterize patients with Vogt–Koyanagi–Harada (VKH) disease with choroidal folds (CFs) and determine how the foveal choroidal thickness changes after initial treatment using high-penetration optical coherence tomography (HP-OCT). Methods In this retrospective observational study, we analyzed 42 eyes of 21 patients with new-onset VKH disease to determine the demographic and clinical differences between patients with and without CFs. Results Twenty-four eyes (57.1 %) of 13 patients with VKH disease had CFs. The mean age ( p  = 0.0009) of patients with CFs was significantly higher than that of those without CFs (49.1 vs 39.4 years respectively ...

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    4. Analysis of Retinal Nonperfusion Using Depth-Integrated Optical Coherence Tomography Images in Eyes with Branch Retinal Vein Occlusion

      Analysis of Retinal Nonperfusion Using Depth-Integrated Optical Coherence Tomography Images in Eyes with Branch Retinal Vein Occlusion

      PURPOSE: To assess the morphology of areas of complete retinal nonperfusion in eyes with branch retinal vein occlusion (BRVO) by enface images of optical coherence tomography (OCT). METHODS: Forty-six eyes with BRVO which underwent swept-source OCT (SS-OCT) and fluorescein angiography were enrolled. Depth-integrated images of the neural retina delineated by automated segmentation algorithm were obtained using SS-OCT. The findings in a 6 x 6-mm area on enface SS-OCT scans at the area of retinal nonperfusion were evaluated. RESULTS: Retinal nonperfusion was detected in twenty-five eyes. Of these, twenty (80%) eyes had multiple concaves of low reflectivity within an area of ...

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    5. Ophthalmological Imaging Apparatus And Ophthalmological Image Display Device

      Ophthalmological Imaging Apparatus And Ophthalmological Image Display Device

      Provided is a novel technique for ophthalmological image diagnosis. The ophthalmological imaging apparatus according to an embodiment comprises: an acquisition unit for acquiring three dimensional image data for an eye being tested using optical coherence tomography; a designating section for designating partial image data, which is a portion of the three dimensional image data that corresponds to a specified region of the eye being tested; a modifying section for generating new three dimensional data by modifying the three dimensional data so that said partial image data is modified to a previously established form; a forming section for forming cross-sectional image ...

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    6. En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy

      Aim To observe the choroidal microstructure in polypoidal choroidal vasculopathy (PCV) using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source that visualises tissue beneath the retinal pigment epithelium (RPE) and deep choroid, and to compare the findings with those of indocyanine green angiography (ICGA). Methods In this retrospective, non-invasive, observational case series, 19 eyes (18 patients) with PCV were observed using HP-OCT (swept source, 100 000 A-scans/s, 1060 nm wavelength) and ICGA. The HP-OCT scan protocol was a 3×3-mm or 6×6-mm square containing 256×256 or 512×128 A-scans. The choroidal thickness (CT) was measured ...

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    7. Choroidal observations in posterior scleritis using high-penetration optical coherence tomography

      Choroidal observations in posterior scleritis using high-penetration optical coherence tomography

      To investigate the choroidal morphologic changes in two patients with posterior scleritis. We used high-penetration optical coherence tomography (HP-OCT) in vivo with a long-wavelength light source (1,060 nm) to view the choroidal changes. In patient 1 with unilateral scleritis, the subfoveal choroidal thickness of the right eye was 418 μm with a serous retinal detachment (SRD) at the initial visit. The treatment regimen was prednisolone 30 mg/day, and the posterior scleritis resolved. Follow-up HP-OCT showed the following choroidal thicknesses—266 μm on day 27 with no SRD, 245 μm on day 69, and 200 μm on day 216 ...

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    8. Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy

      Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy

      Background We compared the visibility of retinal and choroidal pathologies using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source (1,050 nm) and conventional spectral-domain OCT (SD-OCT) in age-related macular degeneration (AMD). Methods One hundred and forty-six eyes were included: 63 eyes with AMD, 79 eyes with polypoidal choroidal vasculopathy (PCV), and four eyes with retinal angiomatous proliferation. The SD-OCT and HP-OCT images were compared using the grading criteria to grade the visibility of the retinal changes, the line corresponding to the retinal pigment epithelium (RPE), and the chorioscleral interface (CSI). In 132 eyes with a pigment epithelial ...

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    9. Correlation of Indocyanine Green Angiography and Optical Coherence Tomography Findings After Intravitreal Ranibizumab for Polypoidal Choroidal Vasculopathy

      Correlation of Indocyanine Green Angiography and Optical Coherence Tomography Findings After Intravitreal Ranibizumab for Polypoidal Choroidal Vasculopathy

      Purpose: To evaluate findings in eyes with polypoidal choroidal vasculopathy on indocyanine green angiography (ICGA) and optical coherence tomography (OCT) over 3 months after ranibizumab treatment. Method: Fifty-one eyes from 51 patients with treatment-naive polypoidal choroidal vasculopathy received intravitreal ranibizumab injections. We evaluated changes in polypoidal lesions on ICGA and OCT and their correlation over 3 months. Ranibizumab was injected again based on the presence of residual fluid on OCT. Results: Indocyanine green angiography detected 75 polypoidal lesions. All corresponding OCT lesions showed baseline protrusion of the retinal pigment epithelium. At 3 months, 26 lesions (35%) resolved on ICGA: retinal ...

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    10. Choroidal observations in Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography

      Choroidal observations in Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography
      Background The aim of this work was to investigate the choroidal morphologic changes of Vogt–Koyanagi–Harada (VKH) disease in vivo using high-penetration optical coherence tomography (HP-OCT) with a long-wavelength light source (1,060 nm). Methods Fourteen patients with VKH disease were included in this study: 12 eyes of six patients with treatment-naive acute VKH in the first 6–12 months after diagnosis and 16 eyes of eight patients in the convalescent phase with a sunset glow fundus appearance. A prototype HP-OCT instrument was used to observe the deep choroid and sclera. The choroidal thickness was measured for more than ...
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    11. Adaptive Optics Fundus Camera to Examine Localized Changes in the Photoreceptor Layer of the Fovea

      Purpose: To examine highly localized photoreceptor disruptions in the fovea by a high-resolution adaptive optics (AO) fundus camera combined with Fourier-domain optical coherence tomography (FD OCT).Design: Observational case series.Participants: Three eyes of 3 patients who showed dark foveal spots by slit-lamp biomicroscopy.Methods: Three patients who reported metamorphopsia but showed no changes in the retina in conventional fundus photographs were examined. High-resolution retinal images were obtained with the AO fundus camera and by FD OCT. The images were compared with the findings obtained by standard clinical tests, including Amsler charts and fluorescein angiography (FA).Main Outcome Measures: Quantitative ...
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      Mentions: Osaka University
    12. Morphologic Changes in Acute Central Serous Chorioretinopathy Evaluated by Fourier-Domain Optical Coherence Tomography

      Objective: To investigate morphologic alterations around fluorescein leakage sites using Fourier-domain optical coherence tomography (FD OCT) in acute central serous chorioretinopathy (CSC).Design: Observational case series.Participants: Twenty-one eyes with acute CSC with subjective symptoms for under 3 months.Methods: Patients underwent measurement of visual acuity, fundus observations, and FD OCT examinations at every visit with the intervals of 2 to 4 weeks until subretinal fluid (SRF) resolved. Fluorescein angiography was performed at baseline to confirm dye leakage sites. Horizontal and vertical OCT scans (B-scans and consecutive raster scans) of the fovea and fluorescein leakage sites were obtained.Main Outcome ...
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      Mentions: Osaka University
    1-12 of 12
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    Choroidal observations in Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography Correlation of Indocyanine Green Angiography and Optical Coherence Tomography Findings After Intravitreal Ranibizumab for Polypoidal Choroidal Vasculopathy Comparison of spectral-domain and high-penetration OCT for observing morphologic changes in age-related macular degeneration and polypoidal choroidal vasculopathy Choroidal observations in posterior scleritis using high-penetration optical coherence tomography En-face high-penetration optical coherence tomography imaging in polypoidal choroidal vasculopathy Ophthalmological Imaging Apparatus And Ophthalmological Image Display Device Analysis of Retinal Nonperfusion Using Depth-Integrated Optical Coherence Tomography Images in Eyes with Branch Retinal Vein Occlusion Analysis of choroidal folds in acute Vogt–Koyanagi–Harada disease using high-penetration optical coherence tomography Indiana University Receives NIH Grant for Imaging Spatial and Temporal Dynamics of Retinal Ganglion Cells University of Houston Receives NIH Grant for Structural and Molecular Phenotyping of Embryonic Development Through Multi-Modal Optical Imaging. Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography Yale University Receives a NIH Grant for Xenopus As A Model System for Hydrocephaly and Ependymal Ciliogenesis