1. Articles from Nathalie Massamba

    1-11 of 11
    1. Use of Fundus Autofluorescence Combined with Optical Coherence Tomography for Diagnose of Geographic Atrophy in Age-Related Macular Degeneration

      Use of Fundus Autofluorescence Combined with Optical Coherence Tomography for Diagnose of Geographic Atrophy in Age-Related Macular Degeneration

      The aim of this study was to demonstrate the sensitivity of Optical coherence tomography (OCT) in detection of geographic atrophy (GA) secondary to exudative age related macular degeneration (AMD). In this retrospective case series study 77 patients (53% female, with mean ± standard deviation [SD] of 82.6±9.3 years) with 97 eyes (45 OS [left eyes]/52 OD [right eyes]) were included. This was a retrospective review of the charts of patients who presented with exudative AMD at the Pitié Salpetrière Hospital, Paris, France, between December 2016 and August 2017 that received intravitreal injections of anti-vascular endothelial growth ...

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    2. Functional characterization and multimodal imaging of treatment-naïve "quiescent" choroidal neovascularization

      Functional characterization and multimodal imaging of treatment-naïve "quiescent" choroidal neovascularization

      Purpose: To investigate the multimodal morphological and functional characteristics of treatment-naïve "quiescent" choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Methods: Eleven patients with treatment-naïve "quiescent" CNV that consecutively presented over a six-month period, underwent multimodal morphological and functional assessment (including indocyanine green angiography [ICGA], spectral-domain optical coherence tomography [SD-OCT], microperimetry and preferential hyperacuity perimeter [PHP]). For the purpose of this study, asymptomatic previously untreated CNVs showing absence of intraretinal/subretinal exudation in 2 consecutive visits (at least 6 months apart) were defined as treatment-naïve "quiescent" CNV. Results: Eleven eyes of 11 patients (9 females; mean ...

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    3. Reticular Pattern Dystrophy of the Retina: A Spectral-Domain Optical Coherence Tomography Analysis

      Reticular Pattern Dystrophy of the Retina: A Spectral-Domain Optical Coherence Tomography Analysis

      Purpose To analyze the outer retinal and retinal pigment epithelium (RPE) features of reticular pattern dystrophy of the retina using spectral-domain optical coherence tomography (SDOCT). Design Retrospective observational case series. Methods Consecutive patients with reticular pattern dystrophy of the retina underwent a complete ophthalmologic examination, including assessment of best-corrected visual acuity (BCVA), fundus biomicroscopy, fluorescein angiography (FA), and SDOCT. Results Twenty-two eyes of 13 patients (6 men, 7 women, mean age 68.6 ± 14.5 years) were included. In the foveal area, the RPE layer appeared normal in 45.5% of eyes, while small RPE elevations and RPE bumps were ...

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    4. Spectral-Domain Optical Coherence Tomography of Early Onset Large Colloid Drusen

      Spectral-Domain Optical Coherence Tomography of Early Onset Large Colloid Drusen

      Purpose: Large colloid drusen (LCD) are a subgroup of early onset drusen recently reported. The aim of this study was to describe morphologic features in patients affected with LCD using high-resolution spectral-domain optical coherence tomography (SD-OCT). Methods: A complete ophthalmologic examination including SD-OCT was performed in 22 eyes of 11 consecutive patients. Results: Mean age was 35 years old at diagnosis, and mean visual acuity was 20/25. In all eyes, SD-OCT showed multiple dome-shaped retinal pigment epithelium detachments corresponding to the drusen. Mean height of drusen was 199 [mu]m (range, 108-316 [mu]m) and mean width was 419 ...

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    5. En face enhanced depth imaging optical coherence tomography of fibrovascular pigment epithelium detachment

      En face enhanced depth imaging optical coherence tomography of fibrovascular pigment epithelium detachment

      Purpose:To analyze the internal structure of fibrovascular pigment epithelial detachment (FV-PED) due to age-related macular degeneration (AMD) using en face enhanced depth imaging (EDI) spectral-domain optical coherence tomography (SD-OCT). Methods:We enrolled 38 consecutive patients presenting to our hospitals with FV-PED due to AMD. Retinal images were automatically obtained with the Spectralis SD-HRA+OCT; the typical inverted 97 sections at 30µm intervals, each comprised of 9 averaged B-scans, were acquired in less than 60 seconds. The resultant images of en face cross-sections of the choroid (C-scans) were compared with indocyanine green angiography (ICGA) images, currently the only technique available ...

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    6. Analysis of Progression of Reticular Pseudodrusen by Spectral Domain–Optical Coherence Tomography

      Analysis of Progression of Reticular Pseudodrusen by Spectral Domain–Optical Coherence Tomography

      Purpose. To analyze reticular pseudodrusen progression using spectral domain–optical coherence tomography (SD-OCT). Methods. Thirty-three consecutive patients (48 eyes) underwent SD-OCT using the eye-tracked follow-up protocol 24 ± 2 months after baseline examination. Each pair of B-scans (only one per eye was evaluated among those showing pseudodrusen progression) was compared with respect to pseudodrusen appearance and retinal layer structure. Stage 1 pseudodrusen was defined as granular material between the RPE and the inner segment/outer segment (IS/OS), stage 2 as mounds of material sufficient to alter the contour of the IS/OS, stage 3 as thicker material adopting a conical ...

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    7. Analysis of progression of reticular pseudodrusen by spectral domain optical coherence tomography

      Analysis of progression of reticular pseudodrusen by spectral domain optical coherence tomography

      Purpose: To analyze reticular pseudodrusen progression using SD-OCT. Methods: Thirty-three consecutive patients (48 eyes) underwent Spectralis SD-OCT using the eye-tracked follow-up protocol 24+/-2 months after baseline examination. Each pair of B-scans (only 1 per eye was evaluated among those showing pseudodrusen progression) was compared with respect to pseudodrusen appearance and retinal layers structure. Stage 1 pseudodrusen was defined as granular material between the RPE and the IS/OS, stage 2 as mounds of material sufficient to alter the contour of the IS/OS, stage 3 as thicker material adopting a conical appearance and breaking through the IS/OS, and ...

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    8. Three dimensional spectral domain optical coherence tomography features of retinal–choroidal anastomosis

      Three dimensional spectral domain optical coherence tomography features of retinal–choroidal anastomosis

      Background To correlate the three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) features of retinal–choroidal anastomosis (RCA) to conventional angiography. Methods This is a retrospective chart review of consecutive patients diagnosed with RCA who underwent 3D SD-OCT between July 2007 and June 2010. Main outcome measures were the diagnostic capabilities of 3D SD-OCT, and the correlation between 3D findings and the features distinguished by conventional angiography. Results Eighteen eyes of 18 patients [five males, 13 females, mean age 79.5 ± 19.4 years (range, 70–93 years)] were included in the analysis. In eyes (n = 3) showing a focal staining ...

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    9. Natural Course of Adult-Onset Foveomacular Vitelliform Dystrophy: A Spectral-Domain Optical Coherence Tomography Analysis

      Natural Course of Adult-Onset Foveomacular Vitelliform Dystrophy: A Spectral-Domain Optical Coherence Tomography Analysis

      Purpose: To describe the natural course of adult-onset foveomacular vitelliform dystrophy using spectral-domain optical coherence tomography (SD-OCT).Design: Retrospective study.Methods: We reviewed the charts of all consecutive patients with adult-onset foveomacular vitelliform dystrophy who underwent SD-OCT at baseline and at least 12 months later (last visit). Main outcome measures were changes of clinical and SD-OCT features over time.Results: Forty-six eyes (31 patients, 15 male and 16 female; mean age 74.6 ± 8.2 years) were included. Follow-up was 16.2 ± 6 (range, 12–30) months. Visual acuity (VA) reduced from 0.32 ± 0.22 logMAR at baseline to ...

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    10. Analysis of Retinal Flecks in Fundus Flavimaculatus Using High-Definition Spectral-Domain Optical Coherence Tomography

      Analysis of Retinal Flecks in Fundus Flavimaculatus Using High-Definition Spectral-Domain Optical Coherence Tomography

      Purpose: To assess morphologic changes associated with retinal flecks in fundus flavimaculatus using spectral-domain optical coherence tomography (SD-OCT).Design: Observational case series.Methods: Simultaneous recordings of SD-OCT and confocal scanning laser ophthalmoscope (cSLO) fundus autofluorescence images were obtained in fundus flavimaculatus patients. Morphologic aspects of the retinal flecks were analyzed and classified.Results: Thirty-one eyes of 17 consecutive patients (8 male, 9 female; mean age 47.9 ± 17.1 years) were included for analysis. SD-OCT revealed 5 distinct types of lesions. Group A lesions were limited to the outer segment (OS) of the photoreceptors, the retinal pigment epithelium (RPE) interdigitations ...

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    1-11 of 11
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    1. (10 articles) Nathalie Massamba
    2. (9 articles) Centre Hospitalier Intercommunal de Créteil
    3. (9 articles) Eric H. Souied
    4. (9 articles) Giuseppe Querques
    5. (4 articles) San Raffaele Scientfic Institute
    6. (4 articles) Francesco Bandello
    7. (3 articles) Gabriel J. Coscas
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    Analysis of Retinal Flecks in Fundus Flavimaculatus Using High-Definition Spectral-Domain Optical Coherence Tomography Natural Course of Adult-Onset Foveomacular Vitelliform Dystrophy: A Spectral-Domain Optical Coherence Tomography Analysis Three dimensional spectral domain optical coherence tomography features of retinal–choroidal anastomosis Analysis of progression of reticular pseudodrusen by spectral domain optical coherence tomography Analysis of Progression of Reticular Pseudodrusen by Spectral Domain–Optical Coherence Tomography En face enhanced depth imaging optical coherence tomography of fibrovascular pigment epithelium detachment Spectral-Domain Optical Coherence Tomography of Early Onset Large Colloid Drusen Reticular Pattern Dystrophy of the Retina: A Spectral-Domain Optical Coherence Tomography Analysis Functional characterization and multimodal imaging of treatment-naïve "quiescent" choroidal neovascularization Use of Fundus Autofluorescence Combined with Optical Coherence Tomography for Diagnose of Geographic Atrophy in Age-Related Macular Degeneration Optical microangiography reveals temporal and depth-resolved hemodynamic change in mouse barrel cortex during whisker stimulation Optical coherence tomography for fast bedside imaging, assessment and monitoring of autoimmune inflammatory skin diseases?