1. Articles from Rebekah A. Drezek

    1-4 of 4
    1. Variations in optical coherence tomography resolution and uniformity: a multi-system performance comparison

      Variations in optical coherence tomography resolution and uniformity: a multi-system performance comparison

      Point spread function (PSF) phantoms based on unstructured distributions of sub-resolution particles in a transparent matrix have been demonstrated as a useful tool for evaluating resolution and its spatial variation across image volumes in optical coherence tomography (OCT) systems. Measurements based on PSF phantoms have the potential to become a standard test method for consistent, objective and quantitative inter-comparison of OCT system performance. Towards this end, we have evaluated three PSF phantoms and investigated their ability to compare the performance of four OCT systems. The phantoms are based on 260-nm-diameter gold nanoshells, 400-nm-diameter iron oxide particles and 1.5-micron-diameter silica ...

      Read Full Article
    2. Characterizing the point spread function of retinal OCT devices with a model eye-based phantom

      Characterizing the point spread function of retinal OCT devices with a model eye-based phantom

      We have designed, fabricated, and tested a nanoparticle-embedded phantom (NEP) incorporated into a model eye in order to characterize the point spread function (PSF) of retinal optical coherence tomography (OCT) devices in three dimensions under realistic imaging conditions. The NEP comprises a sparse distribution of highly backscattering silica-gold nanoshells embedded in a transparent UV-curing epoxy. The commercially-available model eye replicates the key optical structures and focusing power of the human eye. We imaged the model eye-NEP combination with a research-grade spectral domain OCT system designed for in vivo retinal imaging and quantified the lateral and axial PSF dimensions across the ...

      Read Full Article
    3. Quantitative tool for rapid disease mapping using optical coherence tomography images of azoxymethane-treated mouse colon

      Quantitative tool for rapid disease mapping using optical coherence tomography images of azoxymethane-treated mouse colon
      Amy M. Winkler, Photini F. S. Rice, Rebekah A. Drezek et al. Optical coherence tomography (OCT) can provide new insight into disease progression and therapy by enabling nondestructive, serial imaging of in vivo cancer models. In previous studies, we have shown the utility of endoscopic OCT for identifying adenomas in the azoxymethane-treated mouse model of co ... [J. Biomed. Opt. 15, 041512 (2010)] published Wed Jul 7, 2010.
      Read Full Article
    4. Fluorescent and scattering contrast agents in a mouse model of colorectal cancer

      Fluorescent and scattering contrast agents in a mouse model of colorectal cancer
      Amy M. Winkler, Photini F. S. Rice, Timothy S. Troutman et al. In previous work we have demonstrated the utility of laser-induced fluorescence (LIF) and optical coherence tomography (OCT) to identify adenoma in mouse models of colorectal cancer with high sensitivity and specificity. However, improved sensitivity to early disease, as well as the ability to disti ... [Proc. SPIE Int. Soc. Opt. Eng. 6851, 68510L (2008)] published Tue Feb 5, 2008.
      Read Full Article
    1-4 of 4
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (3 articles) Rice University
    2. (2 articles) University of Maryland
    3. (2 articles) FDA
    4. (2 articles) University of Arizona
    5. (2 articles) Anant Agrawal
    6. (2 articles) Yu Chen
    7. (2 articles) Amy M. Winkler
    8. (2 articles) Photini F. S. Rice
    9. (1 articles) Marek Romanowski
    10. (1 articles) Jennifer K. Barton
  3. Popular Articles

  4. Picture Gallery

    Fluorescent and scattering contrast agents in a mouse model of colorectal cancer Quantitative tool for rapid disease mapping using optical coherence tomography images of azoxymethane-treated mouse colon Characterizing the point spread function of retinal OCT devices with a model eye-based phantom Variations in optical coherence tomography resolution and uniformity: a multi-system performance comparison In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography Spectral Domain – Optical Coherence Tomography findings in Triple-A Syndrome – A case series from Pakistan Feasibility of microscope-integrated swept-source optical coherence tomography in canaloplasty A preliminary study of post-progressive nail-art effects on in vivo nail plate using optical coherence tomography-based intensity profiling assessment Analysis of the Choroid and Its Relationship with the Outer Retina in Patients with Diabetes Mellitus Using Binarization Techniques Based on Spectral-Domain Optical Coherence Tomography Quantifying the Pattern of Retinal Vascular Orientation in Diabetic Retinopathy Using Optical Coherence Tomography Angiography Swept‐source optical coherence tomography objective composite activity score for uveitis