1. Articles from amod gupta

    1-17 of 17
    1. Optical coherence tomography angiography versus fluorescein angiography in diagnosing choroidal neovascularization in chronic central serous chorioretinopathy

      Optical coherence tomography angiography versus fluorescein angiography in diagnosing choroidal neovascularization in chronic central serous chorioretinopathy

      Purpose: Diagnosis of choroidal neovascular membrane (CNVM) is difficult in chronic central serous chorioretinopathy (CCSC) due to overlapping features of both on conventional dye angiography. Optical coherence tomography angiography (OCTA) allows a quick and noninvasive detection of CNVM in these eyes. We compared the fluorescein angiography (FA) features of CNVM with those of OCTA to assess the role of FA in detecting CNVM in CCSC eyes. Methods: Patients with CCSC undergoing FA, spectral domain (SD)-OCT, and OCTA were identified (March 2015–June 2015). Four retina specialists individually reviewed FA images (without OCTA and SD-OCT) to determine whether CNVM was ...

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    2. Spectral domain optical coherence tomography changes following intravitreal dexamethasone implant, Ozurdex ® in patients with uveitic cystoid macular edema

      Spectral domain optical coherence tomography changes following intravitreal dexamethasone implant, Ozurdex ® in patients with uveitic cystoid macular edema

      Purpose: To correlate the structural and functional changes following intravitreal injection of dexamethasone 0.7 mg (Ozurdex ® ) implant in patients with recalcitrant uveitic cystoid macular edema (CME). Materials and Methods: In a prospective, interventional, nonrandomized study, 30 eyes (27 patients) with uveitic CME received Ozurdex ® implant and were followed-up for 24 weeks at periodic intervals to monitor structural alterations seen on spectral domain optical coherence tomography (SD-OCT). The outcome measures included change in central macular thickness (CMT) and best-corrected visual acuity (BCVA) as well as structural alterations seen on OCT such as change in the height of cystoid spaces (CSs ...

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    3. Comparison of event-based analysis of glaucoma progression assessed subjectively on visual fields and retinal nerve fibre layer attenuation measured by optical coherence tomography

      Comparison of event-based analysis of glaucoma progression assessed subjectively on visual fields and retinal nerve fibre layer attenuation measured by optical coherence tomography

      The purpose is to study the ability of an event-based analysis of retinal nerve fibre layer (RNFL) attenuation measured by Stratus ® optical coherence tomography (OCT) and to detect progression across the spectrum of glaucoma. Adult glaucoma suspects, ocular hypertensives and glaucoma patients who had undergone baseline RNFL thickness measurement on Stratus OCT and reliable automated visual field examination by Humphrey’s visual field analyser prior to March 2007 and had 5-year follow-up data were recruited. Progression on OCT was defined by two criteria: decrease in average RNFL thickness from baseline by at least 10 and 20 µ. Visual field progression was ...

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    4. CHOROIDAL GRANULOMAS VISUALIZED BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY

      CHOROIDAL GRANULOMAS VISUALIZED BY ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY

      Purpose: To assess the visualization of choroidal granulomas (CG) by enhanced depth imaging optical coherence tomography (EDI-OCT) and to describe their EDI-OCT characteristics. Methods: Combined indocyanine green (ICG) angiography and EDI-OCT images of 44 CG (sarcoid, tubercular, or Vogt-Koyanagi-Harada related) were reviewed. By ICG angiography, CG were classified as full thickness or partial thickness and as small or large. Two independent operators evaluated EDI-OCT scans over granulomas to record their characteristics (full thickness/partial thickness, shape, reflectivity, internal pattern, margins, and shadowing/increased transmission effect). The agreement between ICG angiography and EDI-OCT, the interobserver agreement, and the correlations between EDI-OCT ...

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    5. ENHANCED DEPTH IMAGING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY VERSUS ULTRASONOGRAPHY B-SCAN FOR MEASURING RETINOCHOROIDAL THICKNESS IN NORMAL EYES

      ENHANCED DEPTH IMAGING SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY VERSUS ULTRASONOGRAPHY B-SCAN FOR MEASURING RETINOCHOROIDAL THICKNESS IN NORMAL EYES

      Purpose: To assess the accuracy of retinochoroidal thickness measurements obtained by ultrasonography (USG) B-Scan (over eyelids) and high-resolution immersion USG (with lids open) compared with enhanced depth imaging optical coherence tomography (EDI-OCT) in normal subjects. Methods: Retinochoroidal thickness measurements were performed in normal subjects using USG over eyelids and high-resolution immersion USG (with lids open) using the 20-MHz probe keeping EDI-OCT as the gold standard. Mean retinochoroidal thickness at the fovea, 1.5 mm nasally and temporally were analyzed for interobserver agreement using intraclass correlation coefficient test. Paired t-test was used to compare the values obtained by the three techniques ...

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    6. Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma Fourth Edition (Book)

      Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma Fourth Edition (Book)

      Optical Coherence Tomography (OCT) is a non-invasive, non contact, transpupillary imaging technology which can image two-dimensional retinal structures in vivo with a resolution of 10 to 17 microns. The fourth edition of this atlas has been completely updated to provide the latest thinking and technology developments in the use of OCT in macular diseases and glaucoma. Beginning with an introduction to OCT, the following section discusses its use with a range of conditions and disorders associated with macular diseases such as macular hole, foveal haemorrhage and retinal trauma. The final section examines the use of OCT for diagnosis and management ...

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    7. High-resolution spectral domain optical coherence tomography and fundus autofluorescence correlation in tubercular serpiginouslike choroiditis

      High-resolution spectral domain optical coherence tomography and fundus autofluorescence correlation in tubercular serpiginouslike choroiditis
      OBJECTIVE: This study aims to describe changes in high-resolution spectral domain optical coherence tomography (SD-OCT) scans with simultaneous fundus autoflorescence (FAF) signals in tubercular serpiginouslike choroiditis (SLC). METHODS: Simultaneous SD-OCT and FAF imaging of eyes affected with SLC from acute stage until resolution of lesions was obtained using Spectralis HRA+OCT system (Heidelberg Engineering, Heidelberg, Germany). PATIENTS: Four eyes (three patients) with SLC were prospectively followed. RESULTS: Acute lesions of SLC (diffusely hyperautofluorescent) corresponded to hyperreflective areas on SD-OCT involving the retinal pigment epithelium (RPE), photoreceptor outer segment tips (POST), inner segment-outer segment (IS/OS) junction, external limiting membrane (ELM ...
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    8. Retinal nerve fiber layer measurement and diagnostic capability of spectral-domain versus time-domain optical coherence tomography

      Retinal nerve fiber layer measurement and diagnostic capability of spectral-domain versus time-domain optical coherence tomography
      Purpose. To compare retinal nerve fiber layer (RNFL) thickness and diagnostic capability of spectral-domain (CirrusTM) versus time-domain (Stratus®) optical coherence tomography (OCT). Methods. A total of 123 eyes of 123 subjects including 68 normal, 32 glaucoma suspect, and 23 patients with glaucoma were prospectively recruited for the study. All subjects were scanned by Stratus® and CirrusTM OCT in the same session. Average and quadrant peripapillary RNFL measurements by both machines were correlated using Spearman correlation coefficient, and agreement between testing methods was analyzed by Bland-Altman plots. The area under receiver operating characteristic curves (AUC) for glaucoma diagnosis was calculated. Results ...
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    9. Reversible retinal changes in the acute stage of sympathetic ophthalmia seen on spectral domain optical coherence tomography

      Reversible retinal changes in the acute stage of sympathetic ophthalmia seen on spectral domain optical coherence tomography
      Abstract  To report the changes seen in the photoreceptor layer during the acute phase of sympathetic ophthalmia. Six consecutive patients diagnosed with sympathetic ophthalmia were enrolled in the study. All 6 patients had a fundus fluorescein angiogram and spectral domain optical coherence tomography (OCT) scan carried out at presentation. The outer retinal segment was demarcated on the raster line scan between the external limiting membrane (ELM) and the retinal pigment epithelium (RPE)–choriocapillaris complex. All patients received intravenous methylprednisolone followed by oral corticosteroids 1–1.5 mg/kg/day. The serial follow-up OCT scans taken 48 h after the initiation ...
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    10. Correlation of Frequency-doubling Perimetry With Retinal Nerve Fiber Layer Thickness and Optic Disc Size in Ocular Hypertensives and Glaucoma Suspects

      Correlation of Frequency-doubling Perimetry With Retinal Nerve Fiber Layer Thickness and Optic Disc Size in Ocular Hypertensives and Glaucoma Suspects
      Purpose: To determine the structure-function correlation using frequency-doubling technology (FDT) perimetry and optical coherence tomography (OCT) in glaucoma suspects, and analyze their relationship to optic disc size. Methods: Sixty eyes of 60 ocular hypertensive patients (OHT) and 54 eyes of 54 subjects with optic disc features suspicious of glaucoma (disc suspects) with normal visual fields on Standard Achromatic Perimetry were recruited. All subjects underwent FDT perimetry using the N-30 program, and the mean deviation (FDT-MD) and FDT-pattern SD were computed. Average and inferior retinal nerve fiber layer (RNFL) thickness and disc area were measured on Stratus OCT. Pearson correlation coefficient ...
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    11. Spectral domain optical coherence tomography predates fluorescein angiography in diagnosing central serous chorioretinopathy

      Spectral domain optical coherence tomography predates fluorescein angiography in diagnosing central serous chorioretinopathy
      Dear Editor: Central serous chorioretinopathy (CSCR) is characterized by the development of serous retinal detachment in the macula and is mainly diagnosed by fluorescein angiography that shows one or multiple areas of leakage from the retinal pigment epithelium (RPE) seen as "expanding dot" or "smoke stack" sign. [1],[2] The RPE defect corresponding to the dominant hyperfluorescence in the fluorescein angiogram, is believed to be the cause for serous leakage of fluid into the subretinal space and is seen as a pigment epithelium detachment (PED) on time domain Stratus Optical coherence tomography (OCT). [3] We present a case of CSCR ...
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    12. Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma, 3rd Edition with DVD ROM (Book)

      Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma, 3rd Edition with DVD ROM (Book)
      In this “ Atlas” , we share our experience of Stratus “OCT” in various macular disorders where we found it helpful in diagnosing and monitoring the response to various therapies and interventions and above all identifying the correct therapeutic. Approach in a given patient. It finds extensive application in diagnosis, management and follow up of diabetic macular edema, macular hole, idiopathic central serous chorioretinopathy and many more areas
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    13. Fixed diameter scan protocol preferable for retinal nerve fiber layer measurement by Optical Coherence Tomography in all sizes of optic discs

      Background: Retinal nerve fiber layer(RNFL) measurements using a fixed-diameter versus a user-defined scan-protocol of optical coherence tomography(Stratus OCT©) were compared in 32 normal, 62 glaucoma suspects and 36 glaucomatous eyes. Methods: Peripapillary RNFL thickness was measured using the standard "Fast"RNFL scan-protocol and Proportional 2.27xdisc scan-protocol. Disc size was measured using "Fast" Optic Disc protocol. Correlation between RNFL thickness by each scan-protocol and disc size was analyzed. Results: In normal eyes, RNFL thickness was independent of optic-disc area using the fixed-diameter protocol(p=0.92), but was inversely proportional to disc size using proportional protocol(p<0 ...
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    14. Morphological changes in the retinal pigment epithelium on spectral-domain OCT in the unaffected eyes with idiopathic central serous chorioretinopathy

      Abstract  Purpose To report the changes seen in the retinal pigment epithelium (RPE) morphology in the asymptomatic eyes of patients with idiopathic central serous chorioretinopathy (ICSC) using spectral-domain Cirrus TM high-definition optical coherence tomography (HD-OCT). Methods In a prospective case series, 17 consecutive patients with unilateral ICSC underwent spectral-domain Cirrus TM HD-OCT scans for both affected and opposite asymptomatic eye. Three-dimensional single-layer RPE map was studied in both eyes for morphological alterations, and findings were correlated with clinical presentation, fluorescein angiogram, and 5 Line raster scan. Additionally, three-dimensional (3D) single-layer RPE maps done in 111 healthy volunteers served as control ...
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    15. Spectral-Domain Cirrus Optical Coherence Tomography of Choroidal Striations Seen in the Acute Stage of Vogt-Koyanagi-Harada Disease

      Purpose: To describe changes in the retinal pigment epithelium (RPE) corresponding to the choroidal striations in acute-stage Vogt-Koyanagi-Harada (VKH) disease.Design: Prospective, consecutive case series.Methods: Four patients (eight eyes) with acute-stage VKH disease were studied. All underwent fundus fluorescein angiography (FFA), ultrasonography, and spectral-domain optical coherence tomography (SD OCT). The main outcome measure was the correlation of the findings seen on a 3-dimensional (3D) single-layer RPE map constructed on SD OCT with the serous retinal detachment (RD) and choroidal striations.Results: The retina inner to external limiting membrane did not show any structural alteration in any of the eyes ...
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    16. Atlas of Optical Coherence Tomography of Macular Diseases (Book)

      Atlas of Optical Coherence Tomography of Macular Diseases (Book)
      In real time, optical coherence tomography (OCT) provides high-resolution cross-sectional images of the macula very similar to those obtained by in vivo histopathological sections. OCT represents a major advance in the diagnostics of retinal disease and has found rapid acceptance among retinal specialists worldwide. OCT is not a substitute for a thorough clinical examination, fundus imaging or various angiographic techniques, but a superb adjunctive tool for probing the mysteries of retinal disease. Throughout this highly illustrated text of both normal and diseased appearances, OCT images are accompanied by fluorescein angiograms and standard fluoroscopic scans, thereby providing the reader with an ...
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    1-17 of 17
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    Atlas of Optical Coherence Tomography of Macular Diseases (Book) Spectral domain optical coherence tomography predates fluorescein angiography in diagnosing central serous chorioretinopathy Reversible retinal changes in the acute stage of sympathetic ophthalmia seen on spectral domain optical coherence tomography Retinal nerve fiber layer measurement and diagnostic capability of spectral-domain versus time-domain optical coherence tomography High-resolution spectral domain optical coherence tomography and fundus autofluorescence correlation in tubercular serpiginouslike choroiditis Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma, 3rd Edition with DVD ROM (Book) Atlas Optical Coherence Tomography of Macular Diseases and Glaucoma Fourth Edition (Book) Repeatability of Optical Coherence Tomography Angiography Measurements in Patients with Retinal Vein Occlusion Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study Anterior‐segment optical coherence tomography of filtering blebs in the early postoperative period of ab externo SIBS microshunt implantation with mitomycin C: Morphological analysis and correlation with intraocular pressure reduction Combining artificial intelligence and robotics: a novel fully automated optical coherence tomography-based approach for eye disease screening Impact of fundus pigmentation on retinal layer visibility on investigational bedside optical coherence tomography in preterm infants