1. Articles from Peng Lee

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    1. Speckle properties of the logarithmically transformed signal in optical coherence tomography

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      Speckle properties of the logarithmically transformed signal in optical coherence tomography

      We discuss the statistical properties of speckle of the logarithmically transformed signal in optical coherence tomography (OCT) both theoretically and experimentally. OCT signals of Intralipid solution with different volume particle concentrations ρ (correspondingly, scattering coefficient μs ranges from 1.25 to 25.11 mm−1) were measured and analyzed under two different focusing conditions [numerical apertures (NAs) of the objective lens of 0.13 and 0.25]. We found that the effect of the speckle noise can be suppressed by displaying OCT images in the logarithmic scale and by using the objective lens with a higher NA. We also found that ...

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      Mentions: Wanrong Gao Nanjing University of Science and Technology

    2. Performance of single-scattering model versus multiple-scattering model in the determination of optical properties of biological tissue with optical coherence tomography

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      Performance of single-scattering model versus multiple-scattering model in the determination of optical properties of biological tissue with optical coherence tomography

      Tissue optical properties can be determined with optical coherence tomography (OCT) by fitting a model to the OCT signal. Using calibrated samples in the fixed focus geometry, the validity of the single-scattering and multiple-scattering models for both highly scattering and weakly scattering media (scattering coefficients μs ranging from 1.25 to 25.11mm−1) has been investigated. The results show that, with a proper correction for the confocal properties of the sample arm, both models are appropriate to extract the scattering coefficients of weakly scattering media. For highly scattering media, the multiple scattering should be taken into account, and the ...

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      Mentions: Wanrong Gao Nanjing University of Science and Technology
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