1. Articles from Desmond Jacob

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    1. Feature Of The Week 6/20/10: Fourier Domain Pump-Probe Optical Coherence Tomography Imaging

      Feature Of The Week 6/20/10: Fourier Domain Pump-Probe Optical Coherence Tomography Imaging

      Feature Of The Week 6/20/10: Researchers from the Laboratory for Optical and Molecular Imaging at Texas A&M; University have recently published on a fusing Optical Coherence Tomography (OCT) imaging with pump-probe spectroscopy. Shown here is a summary of some of their recent work. Contrast in Optical Coherence Tomography (OCT) is primarily derived from local variations in the scattering coefficient, which does not vary widely among different molecular species. As a consequence, the ability to resolve specific molecular species with OCT is very limited. However, the extraction of molecular information is highly desirable because it could provide valuable ...

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    2. Fourier Domain Pump-Probe Optical Coherence Tomography Imaging of Melanin

      Fourier Domain Pump-Probe Optical Coherence Tomography Imaging of Melanin
      We report the development of a two-color Fourier domain Pump-Probe Optical Coherence Tomography (PPOCT) system. Tissue phantom experiments to characterize the system performance demonstrated imaging depths in excess of 725 μm, nearly comparable to the base Optical Coherence Tomography system. PPOCT A-line rates were also demonstrated in excess of 1 kHz. The physical origin of the PPOCT signal was investigated with a series of experiments which revealed that the signal is a mixture of short and long lifetime component signals. The short lifetime component was attributed to transient absorption while the long lifetime component may be due to a mixture ...
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    1. (2 articles) Texas A&M University
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