1. Articles from timothy l. jackson

    1-4 of 4
    1. Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS

      Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS

      BACKGROUND AND OBJECTIVE: The aim of this study was to assess changes in retinal structure and thickness after subretinal implantation of the Retina Implant Alpha IMS (Retina Implant AG, Reutlingen, Germany). PATIENTS AND METHODS: Spectral-domain optical coherence tomography (SD-OCT) imaging was performed to assess the structure and thickness of the retina anterior to the microphotodiode array preoperatively, within 6 weeks and 6 months ± 1 month after implantation. Thickness measurements were performed using the distance tool of the built-in software. Three thickness measurements were performed in each of the four quadrants of the retina on the microchip within 6 weeks and ...

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    2. Epimacular Brachytherapy for Neovascular Age-Related Macular Degeneration (CABERNET) Fluorescein Angiography and Optical Coherence Tomography

      Epimacular Brachytherapy for Neovascular Age-Related Macular Degeneration (CABERNET) Fluorescein Angiography and Optical Coherence Tomography

      Purpose To report the fluorescein angiography (FA) and optical coherence tomography (OCT) results of a clinical trial of epimacular brachytherapy (EMBT) used for the treatment of neovascular age-related macular degeneration (AMD). Design Pivotal multicenter, active-controlled, randomized clinical trial. Participants A total of 494 participants with treatment-naïve, neovascular AMD. Methods Participants with classic, minimally classic, and occult lesions were randomized to receive (a) EMBT and 2 mandated monthly ranibizumab injections followed by pro re nata (PRN) ranibizumab or (b) 3 mandated monthly ranibizumab injections followed by mandated quarterly plus PRN ranibizumab. Participants underwent FA at screening and at months 1 ...

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    3. Macular Epiretinal Brachytherapy in Treated Age-Related Macular Degeneration (MERITAGE Study) 12 Month Optical Coherence Tomography and Fluorescein Angiography

      Macular Epiretinal Brachytherapy in Treated Age-Related Macular Degeneration (MERITAGE Study) 12 Month Optical Coherence Tomography and Fluorescein Angiography

      Purpose To report the optical coherence tomography (OCT) and fundus fluorescein angiography (FFA) results of the Macular Epiretinal Brachytherapy in Treated Age-Related Macular Degeneration study. Design Prospective, multicenter, interventional, noncontrolled clinical trial. Participants Fifty-three eyes of 53 participants with chronic, active neovascular age-related macular degeneration (AMD) requiring frequent anti–vascular endothelial growth factor retreatment. Methods Participants underwent pars plana vitrectomy with a single 24-gray dose of epimacular brachytherapy (EMB), delivered with an intraocular, handheld, cannula containing a strontium 90/yttrium 90 source positioned over the active lesion. Participants were retreated with ranibizumab administered monthly as needed, using predefined retreatment criteria ...

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    4. Retreatment of full-thickness macular hole: predictive value of optical coherence tomography

      Aim: To determine whether the efficacy of re-operation for idiopathic full-thickness macular hole (FTMH) remaining open after initial surgery with internal limiting membrane (ILM) peeling is correlated with macular hole configuration as determined by optical coherence tomography (OCT), macular hole size, macular hole duration before the first operation, or type of tamponade (gas or silicone oil). Methods: A retrospective consecutive interventional case series of 28 patients (28 eyes) with a persisting macular hole after vitrectomy, ILM peel, and gas tamponade. 28 patients underwent repeat surgery involving vitrectomy and gas (n = 15) or silicone oil tamponade (n = 12) or no tamponade ...
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    1-4 of 4
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