1. Articles from james j. irrgang

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    1. Clinical optical coherence tomography of early articular cartilage degeneration in persons with degenerative meniscal tears

      Clinical optical coherence tomography of early articular cartilage degeneration in persons with degenerative meniscal tears
      Objective: Quantitative and nondestructive methods for clinical diagnosis and staging of articular cartilage degeneration are important to evaluation of potential disease modifying treatments for osteoarthritis. Optical Coherence Tomography (OCT) is a novel imaging technology that can generate microscopic resolution cross-sectional images of articular cartilage in near real time. This study tests the hypotheses that OCT can be used clinically to identify early cartilage degeneration, and that OCT correlates with MRI T2 values and arthroscopy. Methods: Patients undergoing arthroscopy for degenerative meniscal tears were recruited under IRB approved protocols. 30 consecutive subjects completing preoperative 3.0T MRI, arthroscopy, and intraoperative OCT ...
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    2. Clinical diagnosis of potentially treatable early articular cartilage degeneration using optical coherence tomography

      Constance R. Chu, Nicholas J. Izzo, James J. Irrgang et al. A series of bench to operating room studies was conducted to determine whether it is feasible to use optical coherence tomography (OCT) clinically to diagnose potentially reversible early cartilage degeneration. A human cadaver study was performed to confirm the reproducibility of OCT imaging and gr ... [J. Biomed. Opt. 12, 051703 (2007)] published Fri Oct 19, 2007.
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    1-2 of 2
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    1. (2 articles) University of Pittsburgh
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    Clinical optical coherence tomography of early articular cartilage degeneration in persons with degenerative meniscal tears Asynchronous feature regularization and cross-modal distillation for OCT based glaucoma diagnosis Developments and Clinical Applications of Noninvasive Optical Technologies for Skin Cancer Diagnosis Retinal Pigment Epithelial Changes in Parkinson's Disease: A Spectral Domain Optical Coherence Tomography Study Prognostic Features of Preoperative Optical Coherence Tomography in Retinal Detachments: A systematic review and meta-analysis Automatic assessment of calcified plaque and nodule by optical coherence tomography adopting deep learning model Coronary plaque characterization assessed by delayed enhancement dual-layer spectral CT angiography and optical coherence tomography Use of multimodal dataset in AI for detecting glaucoma based on fundus photographs assessed with OCT: focus group study on high prevalence of myopia Distinctive Morphological Patterns of Complicated Coronary Plaques in Acute Coronary Syndromes: Insights from an Optical Coherence Tomography Study Characterization of Hyperreflective Dots by Structural and Angiographic Optical Coherence Tomography in Patients with Diabetic Retinopathy and Healthy Subjects Long-Term Follow-Up of Macular Perfusion Evaluated by Optical Coherence Tomography Angiography after Rhegmatogenous Retinal Detachment Surgery Optical coherence tomography angiography for the characterisation of retinal microvasculature alterations in pregnant patients with anaemia: a nested case‚Äícontrol study