1. Articles from janos németh

    1-12 of 12
    1. Retinal and choroidal thickness measurements using spectral domain optical coherence tomography in anterior and intermediate uveitis

      Retinal and choroidal thickness measurements using spectral domain optical coherence tomography in anterior and intermediate uveitis

      Background Macular edema is a common cause of visual loss at uveitic patients. The aim of our study was to investigate retinal and choroidal thickness at the macula in anterior (AU) and intermediate (IMU) uveitis and in healthy individuals using spectral domain optical coherence tomography (SD-OCT). Methods Case-control study of 21 patients with AU and 23 patients with IMU and 34 age-matched healthy controls was performed with Spectralis SD-OCT (Heidelberg Engineering, Germany). High resolution SD-OCT scans and macular mapping were applied for automated measurement of retinal thickness. Standardized, masked manual measurement of the choroidal thickness was performed in the center ...

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    2. Retinal thickness measurements with optical coherence biometry and optical coherence tomography

      Retinal thickness measurements with optical coherence biometry and optical coherence tomography

      Aims Macular disorders are investigated generally with optical coherence tomography (OCT). Aim of our study was to investigate the accuracy of optical coherence biometry (partial interferometry) in eyes with increased central retinal thickness (CRT) due to macular diseases. Methods CRT was measured on 12 eyes of 12 patients (age 66.8 ± 5.7 years) by spectral domain OCT (Zeiss Cirrus). Reason of increased CRT was diabetic macular edema in 7 cases, serous neuroretinal detachment in 3 cases, and epiretinal membrane in 2 cases. Optical coherence biometry was performed on the same eyes using Lenstar LS900 (Haag-Streit AG). The Lenstar scans ...

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    3. Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy

      Background Acute severe postoperative endophthalmitis may lead to severe vision loss. The aim of this study was the analysis of macular microstructure imaged by spectral domain optical coherence tomography in patients after pars plana vitrectomy due to postcataract endophthalmitis. Methods A cross sectional study was carried out in 17 patients who had cataract surgery in both eyes and underwent unilateral pars plana vitrectomy due to postcataract endophthalmitis. Postoperative best corrected visual acuity was determined in both eyes. Evaluation of macular thickness, macular volume, peripapillary retinal nerve fiber layer thickness and choroidal thickness using enhanced depth imaging technique was performed by ...

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    4. Optical Coherence Tomography Features of POEMS Syndrome and Castleman Disease-associated Papillopathy

      Optical Coherence Tomography Features of POEMS Syndrome and Castleman Disease-associated Papillopathy

      Purpose : To report ocular symptoms and optical coherence tomography (OCT) features of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. Methods : Case report of two Caucasian patients with POEMS, one of whom also had multicentric Castleman disease. Results : Both patients presented with edema on both optic disks, bilateral macular edema was seen in case 1, and peripapillary choroidal neovascularization was seen on the right side in case 2. OCT confirmed papilledema involving all retinal layers, with additional bilateral peripapillary serous retinal detachment involving the macula in both cases, and peripapillary CNV in case 2. Changes in retinal nerve ...

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    5. A Morphological Study of Retinal Changes in Unilateral Amblyopia Using Optical Coherence Tomography Image Segmentation

      A Morphological Study of Retinal Changes in Unilateral Amblyopia Using Optical Coherence Tomography Image Segmentation

      Objective The purpose of this study was to evaluate the possible structural changes of the macula in patients with unilateral amblyopia using optical coherence tomography (OCT) image segmentation. Patients and Methods 38 consecutive patients (16 male; mean age 32.4±17.6 years; range 6–67 years) with unilateral amblyopia were involved in this study. OCT examinations were performed with a time-domain OCT device, and a custom-built OCT image analysis software (OCTRIMA) was used for OCT image segmentation. The axial length (AL) was measured by a LenStar LS 900 device. Macular layer thickness, AL and manifest spherical equivalent refraction (MRSE ...

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    6. In Vivo Evaluation of Retinal Neurodegeneration in Patients with Multiple Sclerosis

      In Vivo Evaluation of Retinal Neurodegeneration in Patients with Multiple Sclerosis
      To evaluate macular morphology in the eyes of patients with multiple sclerosis (MS) with or without optic neuritis (ON) in previous history. Optical coherence tomography (OCT) examination was performed in thirty-nine patients with MS and in thirty-three healthy subjects. The raw macular OCT data were processed using OCTRIMA software. The circumpapillary retinal nerve fiber layer (RNFL) thickness and the weighted mean thickness of the total retina and 6 intraretinal layers were obtained for each
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    7. OCT Imaging of Lid-Parallel Conjunctival Folds in Soft Contact Lens Wearers

      OCT Imaging of Lid-Parallel Conjunctival Folds in Soft Contact Lens Wearers
      Purpose. To visualize, using Fourier-domain optical coherence tomography (FD-OCT), the alterations in lid-parallel conjunctival fold (LIPCOF) morphology in eyes with contact lenses and after their removal. Methods. One randomly selected eye of each of 24 volunteers with normal ocular surface status was examined using FD-OCT. The study group included 18 female and 6 male subjects, with a mean age of 28.9 years (range, 18–50 years). The presence, height, and number of conjunctival folds and the tear meniscus area were evaluated by FD-OCT, and the difference between “before and after lens removal” were analyzed by the Wilcoxon signed-rank test ...
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    8. The structure and function of the macula in patients with advanced retinitis pigmentosa

      The structure and function of the macula in patients with advanced retinitis pigmentosa
      Purpose: To assess the structure and function of the macula in advanced retinitis pigmentosa (RP). Methods: Twenty-nine eyes of 22 patients with RP were compared against 17 control eyes. Time-domain optical coherence tomography (OCT) data were processed using OCTRIMA as a means of quantifying Stratus OCT images. The thickness of the retinal nerve fiber layer (RNFL), ganglion cell layer and inner plexiform layer complex (GCL+IPL), inner nuclear layer and outer plexiform layer complex (INL+OPL) and the outer nuclear layer (ONL) were measured. Multifocal electroretinography (mfERG) was performed; two groups were formed based on the mfERG findings. Fourteen eyes ...
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    9. Imaging lid-parallel conjunctival folds with OCT and comparing its grading with the slit lamp classification in dry eye patients and normal subjects

      Imaging lid-parallel conjunctival folds with OCT and comparing its grading with the slit lamp classification in dry eye patients and normal subjects
      Purpose: to visualize and describe the morphological appearance of lid-parallel conjunctival folds (LIPCOF) using optical coherence tomography (OCT) and to relate it to dry eye signs and symptoms. Methods: LIPCOF grade, non-invasive tear film break-up time (NIBUT), lipid layer's interference pattern and dry eye symptoms were recorded in 17 normal and 33 dry eye cases. LIPCOF was evaluated with slit lamp and visualized with OCT. Three different algorithms for OCT was developed to grade LIPCOF using either tear meniscus height or the covering tear film on the folds evaluated by OCT. Results: The three OCT methods showed significant correlations ...
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    10. Boundary Detection Errors on Optical Coherence Tomography Images in Patients With Diabetic Retinopathy

      BACKGROUND AND OBJECTIVE To study the incidence of boundary detection errors produced by optical coherence tomography measurements in patients with diabetic retinopathy. PATIENTS AND METHODS One hundred sixteen eyes with diabetic retinopathy of 64 consecutive patients with diabetes mellitus were included in this retrospective study. The StratusOCT instrument (Carl Zeiss Meditec, Dublin, CA) with the macular thickness map protocol was used for the examinations. After data acquisition, each scan was analyzed using the retinal thickness (single eye) protocol to evaluate whether there was any misdetection of the retinal boundaries. RESULTS Boundary detection errors were found in 35.3% of eyes ...
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    11. Central corneal thickness measurements with optical coherence tomography and ultrasound pachymetry in healthy subjects and in patients after photorefractive keratectomy

      PURPOSE. To compare central corneal thickness measurements made using two different methods, optical coherence tomography (OCT) and ultrasound pachymetry, applied both in normal eyes and in eyes on which photorefractive keratectomy (PRK) had been performed. A second objective was to assess the intrasession variability of OCT measurements. METHODS. In this prospective study, central corneal thickness was measured in 20 normal subjects (normal group) and in 20 PRK patients using the StratusOCT instrument model 3000 (Carl Zeiss Meditec), and also with an ultrasound pachymeter. Five OCT measurements were performed using the Fast Macular Thickness protocol. Corneal thickness data were obtained with ...
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    12. A Comparison of Macular Structure Imaged by Optical Coherence Tomography in Preterm and Full-Term Children

      purpose. Macular anatomic abnormalities were examined by optical coherence tomography (OCT) imaging in premature children and compared with those of full-term children. methods. In a prospective case–control study, premature patients 7 to 14 years of age were divided into three groups (group I, laser-treated retinopathy of prematurity [ROP]; group II, spontaneously regressed ROP; group III, no ROP), and age-matched children (group IV). All the eligible 74 eyes had normal-appearing posterior pole, myopia ≤3 D, and best corrected visual acuity 1.0. When both eyes of a subject were eligible for the study, one eye was randomly selected (10 eyes ...
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    1-12 of 12
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    Imaging lid-parallel conjunctival folds with OCT and comparing its grading with the slit lamp classification in dry eye patients and normal subjects The structure and function of the macula in patients with advanced retinitis pigmentosa OCT Imaging of Lid-Parallel Conjunctival Folds in Soft Contact Lens Wearers In Vivo Evaluation of Retinal Neurodegeneration in Patients with Multiple Sclerosis A Morphological Study of Retinal Changes in Unilateral Amblyopia Using Optical Coherence Tomography Image Segmentation Spectral domain optical coherence tomography in patients after successful management of postoperative endophthalmitis following cataract surgery by pars plana vitrectomy Retinal thickness measurements with optical coherence biometry and optical coherence tomography Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hosptial Postdoctoral Research Fellowships (In Vivo Microscopy) At Massachusetts General Hospital Circumpapillary and macular vessel density assessment by optical coherence tomography angiography in eyes with temporal hemianopia from chiasmal compression. Correlation with retinal neural and visual field loss Miniaturizing medical imaging, sensing technology On-chip tunable photonic delay line