1. Articles from a. c. boccara

    1-6 of 6

    1. Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology

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      Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology

      Optical Coherence Tomography (OCT) is an efficient technique for in-depth optical biopsy of biological tissues, relying on interferometric selection of ballistic photons. Full-Field Optical Coherence Tomography (FF-OCT) is an alternative approach to Fourier-domain OCT (spectral or swept-source), allowing parallel acquisition of en-face optical sections. Using medium numerical aperture objective, it is possible to reach an isotropic resolution of about 1x1x1 m. After stitching a grid of acquired images, FF-OCT gives access to the architecture of the tissue, for both macroscopic and microscopic structures, in a non-invasive process, which makes the technique particularly suitable for applications in pathology. Here we report ...

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      Mentions: Aquyre Biosciences

    2. Theoretical study of acousto-optical coherence tomography using random phase jumps on ultrasound and light

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      Theoretical study of acousto-optical coherence tomography using random phase jumps on ultrasound and light
      Acousto-optical coherence tomography (AOCT) is a variant of acousto-optic imaging (also called ultrasonic modulation imaging) that makes it possible to get the z resolution with acoustic and optic continuous wave beams. We describe here theoretically the AOCT effect, and we show that the acousto-optic “tagged photons” remain coherent if they are generated within a specific z region of the sample. We quantify the z selectivity for both the “tagged photon” field and for the Lesaffre et al. [Opt. Express17, 18211 (2009)10.1364/OE.17.018211] photorefractive signal.
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      Mentions: ESPCI ParisTech

    3. Acousto-optical coherence tomography using random phase jumps on ultrasound and light

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      Acousto-optical coherence tomography using random phase jumps on ultrasound and light
      Imaging objects embedded within highly scattering media by coupling light and ultrasounds (US) is a challenging approach. In deed, US enable direct access to the spatial localization, though resolution can be poor along their axis (cm). Up to now, several configurations have been studied, giving a millimetric axial resolution by applying to the US a microsecond pulse regime, as is the case with conventional echography. We introduce a new approach called Acousto-Optical Coherence Tomography (AOCT), enabling us to get a millimetric resolution with continuous US and light beams by applying random phase jumps on US and light. An experimental demonstration ...
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      Mentions: Institut d'Optique ESPCI ParisTech

    4. Defocus test and defocus correction in full-field optical coherence tomography

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      Defocus test and defocus correction in full-field optical coherence tomography
      We report experimental evidence and correction of defocus in full-field optical coherence tomography of biological samples owing to mismatch of the refractive index of biological tissues and water. Via a metric based on the image quality, we demonstrate that we are able to compensate this ... [Opt. Lett. 34, 1576-1578 (2009)]
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      Mentions: ESPCI ParisTech

    6. Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology

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      Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology
      A. C. Boccara, R. De Paepe, A. Dubois et al. After our first demonstration of the early alteration of the chloroplast morphology with the use of both Confocal Microscopy and Optical Coherence Tomography (OCT) and the discussion of the biological mechanisms, we develop here the optical part of this work and underline the merits of full field OC ... [Proc. SPIE Int. Soc. Opt. Eng. 6755, 67550E (2007)] published Tue Sep 25, 2007.
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      Mentions: Université Pierre et Marie Curie Institut d'Optique ESPCI ParisTech
    1-6 of 6
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    Full-field optical coherence tomography (oct) and early alterations in chloroplast morphology Defocus test and defocus correction in full-field optical coherence tomography Defocus test and defocus correction in full-field optical coherence tomography Acousto-optical coherence tomography using random phase jumps on ultrasound and light Theoretical study of acousto-optical coherence tomography using random phase jumps on ultrasound and light Multimodal full-field optical coherence tomography on biological tissue: toward all optical digital pathology Normative data and associations of Optical Coherence Tomography Angiography measurements of the macula: The Singapore Malay Eye Study Automatic Segmentation and Measurement of Choroid Layer in High Myopia for OCT Imaging Using Deep Learning In-process monitoring in laser grooving with line-shaped femtosecond pulses using optical coherence tomography Three-dimensional opto-thermo-mechanical model for predicting photo-thermal optical coherence tomography responses in multilayer geometries The role of optical coherence tomography angiography in moderate and advanced primary open-angle glaucoma OCT-angiography follow-up of choroidal neovascularization treated with treat- and- extend aflibercept regimen to avoid over-treatment