1. Articles from M. J. Leahy

    1-4 of 4
    1. The how and why of a $10 optical coherence tomography system

      The how and why of a $10 optical coherence tomography system

      Optical Coherence Tomography (OCT) is the fastest growing medical imaging modality with more than $1Bln worth of scans ordered and over $400M worth of equipment shipped in 2010, just nine years after its commercialization. It is at various stages of acceptance and approvals for eye care, coronary care and skin cancer care and is spreading rapidly to other medical specialties. Indeed, it is the leading success of translation of biophotonics science into clinical practice. Significant effort is being made to provide sufficient evidence for efficacy across a broad range of applications, but more needs to be done to radically reduce ...

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    2. Assessment of psoriatic plaque in vivo with correlation mapping optical coherence tomography

      Assessment of psoriatic plaque in vivo with correlation mapping optical coherence tomography

      Background/Purpose Vascular abnormalities play an acute role in the pathogenesis of psoriasis. In order to characterize vascular involvement in psoriasis and its regular clinical assessment in vivo , non-invasive high speed imaging with high resolution and high sensitivity is needed. Methods The correlation mapping optical coherence tomography (cmOCT) technique was used for in vivo microcirculation imaging of human forearm under normal and psoriatic conditions. The cmOCT technique developed by our group uses dense scanning OCT image acquisition and post-processing software based on correlation statistics. The frequency domain OCT system was used for imaging which acquires a 3D volume of 1024 ...

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    3. Dual-beam optical coherence tomography system for quantification of flow velocity in capillary phantoms

      Dual-beam optical coherence tomography system for quantification of flow velocity in capillary phantoms

      The quantification of (blood) flow velocity within the vasculature has potent diagnostic and prognostic potential. Assessment of flow irregularities in the form of increased permeability (micro haemorrhaging), the presence of avascular areas, or conversely the presence of vessels with enlarged or increased tortuosity in the acral regions of the body may provide a means of non-invasive in vivo assessment. If assessment of dermal flow dynamics were performed in a routine manner, the existence and prevalence of ailments such as diabetes mellitus, psoriatic arthritis and Raynaud's condition may be confirmed prior to clinical suspicion. This may prove advantageous in cases ...

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    4. Design and development of a galvanometer inspired dual beam optical coherence tomography system for flow velocity quantification of the microvasculature

      Design and development of a galvanometer inspired dual beam optical coherence tomography system for flow velocity quantification of the microvasculature
      This paper reports initial experimentation of a dual beam flow velocity estimation setup based on optical coherence tomography (OCT) for biomedical applications. The proposed work incorporates a low cost switching mechanism (rotating galvanometer mirror) for optical signal discrimination between adjacent fiber channels enabling quasisimultaneous multiple specimen scanning. A cascaded interferometric design is used with two sample output arms orientated in parallel to eachother. A cross-correlation computation between these two parallel sample beams yields a relative time delay, enabling assessment and quantification of flow velocities.
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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) National University of Ireland, Galway
    2. (4 articles) Martin J. Leahy
    3. (2 articles) University of Limerick
    4. (1 articles) Roshan Dsouza
    5. (1 articles) Enock Jonathan
    6. (1 articles) Don Bogue
    7. (1 articles) Paul M. McNamara
    8. (1 articles) Hrebesh M. Subhash
    9. (1 articles) Compact Imaging, Inc
    10. (1 articles) University of Southern California
    11. (1 articles) UC Irvine
    12. (1 articles) Qifa Zhou
    13. (1 articles) K. Kirk Shung
    14. (1 articles) Heidelberg Engineering
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    Design and development of a galvanometer inspired dual beam optical coherence tomography system for flow velocity quantification of the microvasculature Dual-beam optical coherence tomography system for quantification of flow velocity in capillary phantoms Assessment of psoriatic plaque in vivo with correlation mapping optical coherence tomography The how and why of a $10 optical coherence tomography system Optical imaging techniques could offer non-invasive method to measure swelling within the brain, new study finds Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension Endoscopic imaging in inflammatory bowel disease: current developments and emerging strategies 2D Ultrasonic Array-based Optical Coherence Elastography Optical coherence tomography angiography in diabetic retinopathy: an updated review Flow signal change in polyps after anti-vascular endothelial growth factor therapy Line-field confocal optical coherence tomography-Practical applications in dermatology and comparison with established imaging methods Optical coherence tomography detection of changes in inner retinal and choroidal thicknesses in patients with early retinitis pigmentosa