1. Articles from Mariacristina Parravano

    1-14 of 14
    1. Structural and optical coherence tomography angiography in myopic choroidal neovascularization: Agreement with conventional fluorescein angiography

      Structural and optical coherence tomography angiography in myopic choroidal neovascularization: Agreement with conventional fluorescein angiography

      Purpose: To evaluate the agreement between fluorescein angiography and structural optical coherence tomography in diagnosing and monitoring the activity of myopic choroidal neovascularization and to provide a comparative analysis with optical coherence tomography angiography. Methods: Thirteen patients with active myopic choroidal neovascularization were prospectively enrolled. At the baseline, 2-month, and 6-month visits, each patient underwent a complete ophthalmological examination, including best-corrected visual acuity assessment, fundus examination, fluorescein angiography, and optical coherence tomography with structural and angiographic assessment. Sensitivity and specificity for all optical coherence tomography parameters were evaluated taking fluorescein angiography as the reference examination. Results: At the baseline, fluorescein ...

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    2. Optical Coherence Tomography Parameters as Predictors of Treatment Response to Eplerenone in Central Serous Chorioretinopathy

      Optical Coherence Tomography Parameters as Predictors of Treatment Response to Eplerenone in Central Serous Chorioretinopathy

      Purpose : To present data on clinical response to eplerenone over a 1-year period in patients with central serous chorioretinopathy (CSC), and to evaluate optical coherence tomography (OCT) variables as predictors of treatment response at 3- and 12-month follow-up visits. Methods : Patients with acute or chronic CSC treated with eplerenone were retrospectively included. Clinical and imaging characteristics were recorded at baseline and at the 3-month and 12-month follow-up visits. Changes from baseline in quantitative measurements were calculated at each follow-up. Logistic regression analysis was computed to correlate clinical and OCT parameters at baseline with response to treatment at 3 and 12 ...

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    3. Prognostic role of optical coherence tomography after switch to dexamethasone in diabetic macular edema

      Prognostic role of optical coherence tomography after switch to dexamethasone in diabetic macular edema

      Aims To analyze the visual outcome after early switch to dexamethasone (DEX) in eyes with diabetic macular edema previously treated with ranibizumab (RNB), based on structural spectral-domain optical coherence tomography (SD-OCT) features. Methods Retrospective study of data from 28 eyes which underwent a loading dose of three monthly RNB injections and were then shifted to DEX implant injection. SD-OCT analysis was performed before switch to DEX (week 12, 12W) according to the presence of integrity of ellipsoid zone (EZ) and external limiting membrane (ELM), disorganization of retinal inner layers (DRIL), and quantity of hyper-reflective spots (HRS). Best-corrected visual acuity (BCVA ...

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    4. Progression of Diabetic Microaneurysms According to the Internal Reflectivity on Structural Optical Coherence Tomography and Visibility on Optical Coherence Tomography Angiography

      Progression of Diabetic Microaneurysms According to the Internal Reflectivity on Structural Optical Coherence Tomography and Visibility on Optical Coherence Tomography Angiography

      Purpose To investigate the progression of diabetic microaneurysms (MAs) according to the spectral-domain optical coherence tomography (SD-OCT) and OCT angiography (OCTA) characteristics and to evaluate their influence on the retinal extracellular fluid accumulation at 1 year follow-up in patients with nonproliferative diabetic retinopathy (NPDR). Design Prospective, observational case series. Methods Fourteen patients with NPDR underwent SD-OCT and OCTA at the baseline and at 1 year follow-up. For all the selected MAs the visibility, the changes of internal reflectivity, graded as hyporeflective, moderate, or hyperreflective, and the extracellular fluid accumulation surrounding each MA on SD-OCT at 1 year were evaluated. The ...

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    5. Indocyanine Green Angiography and Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration

      Indocyanine Green Angiography and Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration

      Purpose : To compare the capability of indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA) in detecting choroidal neovascularization (CNV). Methods : In this prospective study, patients with CNV detected with fluorescein angiography (FA) underwent ICGA and OCTA, spectral domain OCT (SD-OCT), and infrared or fundus color photographs. CNV lesions were outlined on ICGA and OCTA images, and the composition and size of the CNV was documented. Results : One hundred eighty-two eyes were included. With ICGA, well-defined lesions were observed in 37.9%, partly defined in 44.5%, and undefined in 17% of eyes. On OCTA, well-defined, partly defined, and ...

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    6. MORPHOFUNCTIONAL EVALUATION IN DOME-SHAPED MACULA: A MICROPERIMETRY AND OPTICAL COHERENCE TOMOGRAPHY STUDY

      MORPHOFUNCTIONAL EVALUATION IN DOME-SHAPED MACULA: A MICROPERIMETRY AND OPTICAL COHERENCE TOMOGRAPHY STUDY

      Purpose: To investigate retinal sensitivity (Se) in dome-shaped macula (DSM) using microperimetry and to correlate functional findings to specific spectral domain optical coherence tomography features. Methods: Patients affected by DSM in at least 1 eye were consecutively enrolled in a prospective, cross-sectional study. All studied eyes performed best-corrected visual acuity measurement, microperimetry to assess Se and optical coherence tomography to investigate DSM pattern and to measure bulge height and retinal and choroidal thicknesses. Results: Fifty-three eyes of 29 patients were studied. Dome-shaped macula was vertically oriented (V-DSM) in 23 (43.4%), symmetric (S-DSM) in 17 (32.1%), and horizontally oriented ...

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    7. Relationship between internal reflectivity of diabetic microaneurysms on SD-OCT and detection on OCT Angiography

      Relationship between internal reflectivity of diabetic microaneurysms on SD-OCT and detection on OCT Angiography

      Purpose To correlate the appearance of Microaneurysms (MAs) on structural spectral-domain optical coherence tomography (SD-OCT) with their detection on OCT angiography (OCTA) in patients with non-proliferative diabetic retinopathy (NPDR). Design Inter-instrument reliability study. Methods Sixteen patients with NPDR without macular edema underwent SD-OCT and OCTA. To compare MAs seen on OCTA to those on SD-OCT, we superimposed the OCTA superficial capillary plexus (SCP) vascular landmarks onto those of the near infrared. Two observers blinded to patient groupings evaluated reflectivity of MAs on SD-OCT scans, graded as hypo-, moderate, or hyper-reflective, and their visualization at the level of SCP and deep ...

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    8. Early microvascular retinal changes in optical coherence tomography angiography in patients with type 1 diabetes mellitus

      Early microvascular retinal changes in optical coherence tomography angiography in patients with type 1 diabetes mellitus

      Purpose Diabetic retinopathy (DR) can lead to significant vision loss and blindness and has a particularly high prevalence in patients with type 1 diabetes (DM1). In this study, we investigate quantitative differences in optical coherence tomography angiography (OCTA) data between DM1 patients with no or mild signs of retinopathy and non-diabetic subjects. Methods Optical coherence tomography angiography (OCTA) imaging was performed on DM1 patients with no or mild nonproliferative diabetic retinopathy and healthy, age-matched controls. Parafoveal vessel density and foveal avascular zone (FAZ) area in the deep capillary plexus (DCP) and superficial capillary plexus (SCP) were calculated with automated quantification ...

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    9. Optic nerve head and fibre layer imaging for diagnosing glaucoma

      Optic nerve head and fibre layer imaging for diagnosing glaucoma

      The diagnosis of glaucoma is traditionally based on the finding of optic nerve head (ONH) damage assessed subjectively by ophthalmoscopy or photography or by corresponding damage to the visual field assessed by automated perimetry, or both. Diagnostic assessments are usually required when ophthalmologists or primary eye care professionals find elevated intraocular pressure (IOP) or a suspect appearance of the ONH. Imaging tests such as confocal scanning laser ophthalmoscopy (HRT), optical coherence tomography (OCT) and scanning laser polarimetry (SLP, as used by the GDx instrument), provide an objective measure of the structural changes of retinal nerve fibre layer (RNFL) thickness and ...

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    10. Influence of Disc Size on Optic Nerve Head versus Retinal Nerve Fiber Layer Assessment for Diagnosing Glaucoma

      Influence of Disc Size on Optic Nerve Head versus Retinal Nerve Fiber Layer Assessment for Diagnosing Glaucoma
      Purpose: To explore and compare the influence of optic disc size on the diagnostic accuracy of retinal nerve fiber layer (RNFL) thickness and optic nerve head (ONH) quantitative assessment.Design: Observational, cross-sectional evaluation of diagnostic tests.Participants: We included 120 eyes from 50 normal subjects and 70 glaucomatous patients classified by the presence of a repeatable visual field defect for the analysis.Testing: The RNFL thickness was measured by scanning laser polarimetry with variable corneal compensator (GDx-VCC, Carl-Zeiss Meditec, Dublin, CA) and spectral-domain optical coherence tomography (Cirrus HD-OCT, Carl Zeiss Meditec, Inc). We obtained ONH imaging by means of confocal ...
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    11. Reproducibility of Macular Thickness Measurements Using Cirrus Spectral Domain Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration

      Reproducibility of Macular Thickness Measurements Using Cirrus Spectral Domain Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration
      Purpose: to assess test-retest variability of central and sectorial macular thickness measurements obtained by Cirrus HD-OCT in neovascular age related macular degeneration (nAMD). Methods: Macular thickness measurements of 9 standard ETDRS subfields were obtained and analyzed. To assess the repeatability of macular thickness of Cirrus HD-OCT, the intrasession within subject standard deviation (Sw), coefficient of repeatibility (CR), coefficient of variation (CV) were assessed before and after excluding eyes with retinal segmentation errors. Results: A total of 49 nAMD eyes of 49 consecutive patients were included in the study. The CR for the central macular subfield was 42.4 µm (10 ...
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    1-14 of 14
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    1. (5 articles) Giuseppe Querques
    2. (4 articles) Francesco Bandello
    3. (3 articles) Università Vita-Salute San Raffaele
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    Reproducibility of Macular Thickness Measurements Using Cirrus Spectral Domain Optical Coherence Tomography in Neovascular Age-Related Macular Degeneration Influence of Disc Size on Optic Nerve Head versus Retinal Nerve Fiber Layer Assessment for Diagnosing Glaucoma Optic nerve head and fibre layer imaging for diagnosing glaucoma Optical coherence tomography angiography in treated type 2 neovascularization undergoing monthly anti-VEGF treatment Early microvascular retinal changes in optical coherence tomography angiography in patients with type 1 diabetes mellitus Relationship between internal reflectivity of diabetic microaneurysms on SD-OCT and detection on OCT Angiography MORPHOFUNCTIONAL EVALUATION IN DOME-SHAPED MACULA: A MICROPERIMETRY AND OPTICAL COHERENCE TOMOGRAPHY STUDY Indocyanine Green Angiography and Optical Coherence Tomography Angiography of Choroidal Neovascularization in Age-Related Macular Degeneration Deep capillary plexus impairment in patients with type 1 diabetes mellitus with no signs of diabetic retinopathy revealed using optical coherence tomography angiography Progression of Diabetic Microaneurysms According to the Internal Reflectivity on Structural Optical Coherence Tomography and Visibility on Optical Coherence Tomography Angiography Intravitreal Ranibizumab Monotherapy or Combined with Laser for Diabetic Macular Edema (OCT guided study) Prospective evaluation of drug eluting self‐apposing stent for the treatment of unprotected left main coronary artery disease: 1‐year results of the TRUNC study