1. Articles from christian winter

    1-3 of 3
    1. Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast

      Microscopic optical coherence tomography (mOCT) at 600 kHz for 4D volumetric imaging and dynamic contrast

      Volumetric imaging of dynamic processes with microscopic resolution holds a huge potential in biomedical research and clinical diagnosis. Using supercontinuum light sources and high numerical aperture (NA) objectives, optical coherence tomography (OCT) achieves microscopic resolution and is well suited for imaging cellular and subcellular structures of biological tissues. Currently, the imaging speed of microscopic OCT (mOCT) is limited by the line-scan rate of the spectrometer camera and ranges from 30 to 250 kHz. This is not fast enough for volumetric imaging of dynamic processes in vivo and limits endoscopic application. Using a novel CMOS camera, we demonstrate fast 3-dimensional OCT ...

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    2. 3-D intraoperative imaging combining an operating microscope with optical coherence tomography (OCT)

      Objective Optical coherence tomography (OCT) allows non-contact/non-invasive analysis of tissues with a penetration depth of 2–3 mm reaching a spatial resolution of approximately 4–15 μm. This resolution is compatible with the resolution of modern operation microscopes. Aim of this work was to provide a three-dimensional (3D) intraoperative visualization of tissue structures. Material and methods A high-speed spectral domain OCT (a modified version of the Ganymed, Thorlabs HL) was adapted to a motorized operation microscope (HR 1000, Möller-Wedel). Via a specially designed two axis-scanner, the 840 nm OCT was adapted directly to a camera port of the operation ...
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    3. Device And Method For Performing Measurements During A Surgical Intervention By Means Of An Optical Coherence Tomography Device (Wo 2008/034609)

      A device for a therapeutic treatment of the eye by means of a laser is provided, which allows a real-time monitoring of the treatment. In particular, the laser light is supplied to the treatment region via a fibre. The monitoring of the treatment happens by means of optical coherence tomography ( OCT). To this end the OCT measurement beam and the treatment laser light are coupled in a probe that is put onto the eye and allows to focus the OCT measurement beam on the tissue region inside of the eye that is treated at that moment.
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    1-3 of 3
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    1. (2 articles) University of Lübeck
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