1. Articles from Yasushi Takagi

    1-3 of 3
    1. Impact of Statin Therapy on Plaque Characteristics as Assessed by Serial OCT, Grayscale and Integrated Backscatter–IVUS

      Impact of Statin Therapy on Plaque Characteristics as Assessed by Serial OCT, Grayscale and Integrated Backscatter–IVUS

      Objectives: The purpose of this study was to evaluate the effect of statin treatment on coronary plaque composition and morphology by optical coherence tomography (OCT), grayscale and integrated backscatter (IB) intravascular ultrasound (IVUS) imaging. Background: Although previous studies have demonstrated that statins substantially improve cardiac mortality, their precise effect on the lipid content and fibrous cap thickness of atherosclerotic coronary lesions is less clear. While IVUS lacks the spatial resolution to accurately assess fibrous cap thickness, OCT lacks the penetration of IVUS. We used a combination of OCT, grayscale and IB-IVUS to comprehensively assess the impact of pitavastatin on plaque ...

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    2. Coronary CT angiographic characteristics of culprit lesions in acute coronary syndromes not related to plaque rupture as defined by optical coherence tomography and angioscopy

      Coronary CT angiographic characteristics of culprit lesions in acute coronary syndromes not related to plaque rupture as defined by optical coherence tomography and angioscopy

      Aims Pathological and clinical optical coherence tomography (OCT) studies have indicated that acute coronary syndrome (ACS) lesions have either ruptured fibrous caps (RFC-ACS) or intact fibrous caps (IFC-ACS). Although computed tomographic (CT) angiographic characteristics of RFC-ACS include low-attenuation plaques and positive plaque remodelling, features associated with IFC-ACS have not been previously described. The aim of this study was to assess the CT characteristics of IFC-ACS lesions. Methods and results Seventy-four patients with ACS/stable angina consented to multimodality imaging, of which 66 underwent CT angiography. Of these, 57 culprit lesions in 57 patients were evaluated with sufficient image quality from ...

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    3. The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study

      The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study

      Aims To assess the fate of incomplete stent apposition (ISA) after deployment of sirolimus-eluting stents (SESs). Methods and results Thirty-two patients having intravascular ultrasound (IVUS)-guided PCI with SESs underwent assessment of stent deployment with quantitative coronary angiography, IVUS, and optical coherence tomography (OCT) pre-procedure, post-procedure, and at 10 months follow-up. Incomplete stent apposition was defined as separation of a stent strut from the inner vessel wall by >160 µm. At follow-up, 4.67% of struts with ISA at deployment failed to heal and 7.59% which were well apposed did not develop neointimal hyperplasia even after 10 months. Lesion ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) Erasmus University
    2. (3 articles) Patrick W. Serruys
    3. (3 articles) Yukio Ozaki
    4. (2 articles) Royal Brompton Hospital
    5. (2 articles) Jagat Narula
    6. (1 articles) UC Irvine
    7. (1 articles) Imperial College London
    8. (1 articles) Mount Sinai School of Medicine
    9. (1 articles) Renu Virmani
    10. (1 articles) Francesco Prati
    11. (1 articles) Institute of Applied Physics
    12. (1 articles) Medical University of Vienna
    13. (1 articles) Kyungpook National University
    14. (1 articles) Singapore Eye Research Institute
    15. (1 articles) University of Western Australia
    16. (1 articles) Stefan G. Sacu
    17. (1 articles) Brendan F. Kennedy
    18. (1 articles) Yongyang Huang
    19. (1 articles) Jeehyun Kim
    20. (1 articles) Ursula Schmidt-Erfurth
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