1. Articles from Nomdo M. Jansonius

    1-6 of 6
    1. Quantification and Repeatability of Vessel Density and Flux as Assessed by Optical Coherence Tomography Angiograph

      Quantification and Repeatability of Vessel Density and Flux as Assessed by Optical Coherence Tomography Angiograph

      Purpose : To determine the intrasession repeatability (test-retest variability) of parafoveal and peripapillary perfused capillary density (PCD) and normalized flux index (NFI) as assessed with Canon OCT-HS100 angiography. Methods : Pairs of optical coherence tomography angiography (OCT-A) images were obtained from the parafoveal and peripapillary region of 30 eyes of 30 healthy subjects. PCD and NFI were calculated using generic image-processing software. Macular ganglion-cell complex thickness (GCC) and peripapillary retinal nerve fiber layer thickness (RNFLT) were also recorded. Bland-Altman analysis was performed and the coefficient of repeatability (CoR) and intraclass correlation coefficient (ICC) were calculated. Correlations of parafoveal PCD/NFI with GCC ...

      Read Full Article
    2. Retinal layers in Parkinson's disease: A meta-analysis of spectral-domain optical coherence tomography studies

      Retinal layers in Parkinson's disease: A meta-analysis of spectral-domain optical coherence tomography studies

      Background Patients with Parkinson's disease experience visual symptoms , partially originating from retinal changes. Since 2011, multiple case-control studies using spectral-domain OCT, which allows for studying individual retinal layers, have been published. The aim of this study was to substantiate the occurrence, extent, and location of retinal degeneration in Parkinson's by meta-analysis . Methods Spectral-domain OCT case-control data were collected by performing a search in PubMed and Embase with terms: “optical coherence tomography” and “parkinson”, up to November 5th, 2018. Studies with fewer than 10 patients or controls were excluded. We performed a random effects meta-analysis. Heterogeneity was evaluated with ...

      Read Full Article
    3. Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

      Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects

      Purpose To determine the influence of the optic disc–fovea distance (DFD) on the normative classifications based on thickness measurements of macular inner retinal layers with spectral-domain optical coherence tomography (OCT) in healthy subjects. Methods A total of 182 eyes from 182 healthy subjects were included (mean (SD) spherical equivalent −0.8 (1.9) dioptres). We performed macula and optic disc imaging with the Topcon 3D OCT 2000. The thickness of the macular inner retinal layers (macular retinal nerve fibre layer (mRNFL), ganglion cell-inner plexiform layer (GCIPL) and both combined (ganglion cell complex; GCC)) and the corresponding classifications based on ...

      Read Full Article
    4. Influence of coherence length, signal-to-noise ratio, log transform, and low-pass filtering on layer thickness assessment with OCT in the retina

      Influence of coherence length, signal-to-noise ratio, log transform, and low-pass filtering on layer thickness assessment with OCT in the retina

      Optical coherence tomography (OCT) images of the retina are inevitably affected by the finite width of the coherence function and noise. To make low-reflective layers visible, the raw OCT signal is log transformed; to reduce the effect of noise the images can be low-pass filtered. We determined the effects of these operations on layer thickness assessment, as a function of signal-to-noise ratio (SNR), by performing measurements in a phantom eye and modeling. The log transform appeared to be the key factor in a SNR-dependent overestimation of peak widths and a less predictive bias in the widths of low-reflective layers.

      Read Full Article
    5. Optimizing the Information Yield of 3-D OCT in Glaucoma

      Optimizing the Information Yield of 3-D OCT in Glaucoma

      Purpose. To determine, first, which regions of 3-D optical coherence tomography (OCT) volumes can be segmented completely in the majority of subjects and, second, the relationship between analyzed area and thickness measurement test–retest variability. Methods. Three-dimensional OCT volumes (6 × 6 mm) centered around the fovea and optic nerve head (ONH) of 925 Rotterdam Study participants were analyzed; 44 participants were scanned twice. Volumes were segmented into 10 layers, and we determined the area where all layers could be identified in at least 95% (macula) or 90% (ONH) of subjects. Macular volumes were divided in 2 × 2, 4 × 4, 6 ...

      Read Full Article
    6. Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images

      Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images

      The 3-D spectral-domain optical coherence tomography (SD-OCT) images of the retina often do not reflect the true shape of the retina and are distorted differently along the x and y axes. In this paper, we propose a novel technique that uses thin-plate splines in two stages to estimate and correct the distinct axial artifacts in SD-OCT images. The method was quantitatively validated using nine pairs of OCT scans obtained with orthogonal fast-scanning axes, where a segmented surface was compared after both datasets had been corrected. The mean unsigned difference computed between the locations of this artifact-corrected surface after the single-spline ...

      Read Full Article
    1-6 of 6
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (5 articles) University of Groningen
    2. (2 articles) University of Iowa
    3. (2 articles) Milan Sonka
    4. (2 articles) Kyungmoo Lee
    5. (2 articles) Michael D. Abràmoff
    6. (2 articles) Topcon Medical Systems
    7. (1 articles) Erasmus University
    8. (1 articles) Mona K. Garvin
    9. (1 articles) Young H. Kwon
    10. (1 articles) Heidelberg Engineering
    11. (1 articles) Joost Daemen
    12. (1 articles) Notal Vision
    13. (1 articles) Thorlabs
  3. Popular Articles

  4. Picture Gallery

    Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images Optimizing the Information Yield of 3-D OCT in Glaucoma Influence of coherence length, signal-to-noise ratio, log transform, and low-pass filtering on layer thickness assessment with OCT in the retina Effect of optic disc–fovea distance on the normative classifications of macular inner retinal layers as assessed with OCT in healthy subjects Retinal layers in Parkinson's disease: A meta-analysis of spectral-domain optical coherence tomography studies Quantification and Repeatability of Vessel Density and Flux as Assessed by Optical Coherence Tomography Angiograph Fantom Encore Sirolimus-eluting Bioresorbable Scaffold for Treatment of De-novo CAD: the ENCORE-I Study Assessment of Microcirculatory Dysfunction in Septic Shock Patients by OCTA OCT system used at home demonstrates potential for daily monitoring of AMD Optical Coherence Tomography Biomarkers of the Outer Blood—Retina Barrier in Patients with Diabetic Macular Oedema Retinal Boundary Segmentation in Stargardt Disease Optical Coherence Tomography Images Using Automated Multi-channel swept source optical coherence tomography concept based on photonic integrated circuits