1. Articles from qiang wu

    1-14 of 14
    1. Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study

      Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study

      Introduction : This prospective, multicenter, randomized study was designed to analyze the benefits of ticagrelor over clopidogrel in reducing subclinical stent thrombosis (ST) in patients with coronary artery disease who underwent implantation of a second-generation drug-eluting stent (DES). Methods : About 352 patients with single de novo coronary stenosis were randomly assigne`d to either clopidogrel group (aspirin plus clopidogrel) or ticagrelor group (aspirin plus ticagrelor) after DES implantation for 1 year. Baseline clinical characteristics, blood chemistry markers, coronary artery angiography (CAG), and optical coherence tomography (OCT) were obtained during the index procedure. Data about clinic, CAG and OCT were also collected ...

      Read Full Article
    2. Automatic Choroid Layer Segmentation from Optical Coherence Tomography Images Using Deep Learning

      Automatic Choroid Layer Segmentation from Optical Coherence Tomography Images Using Deep Learning

      The choroid layer is a vascular layer in human retina and its main function is to provide oxygen and support to the retina. Various studies have shown that the thickness of the choroid layer is correlated with the diagnosis of several ophthalmic diseases. For example, diabetic macular edema (DME) is a leading cause of vision loss in patients with diabetes. Despite contemporary advances, automatic segmentation of the choroid layer remains a challenging task due to low contrast, inhomogeneous intensity, inconsistent texture and ambiguous boundaries between the choroid and sclera in Optical Coherence Tomography (OCT) images. The majority of currently implemented ...

      Read Full Article
    3. Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography

      Choroidal Variations in Diabetic Macular Edema: Fluorescein Angiography and Optical Coherence Tomography

      Purposes : To (i) evaluate variations in choroidal thickness (CT) and choroidal volume (CV) in diabetic macular edema (DME), as demonstrated by fluorescein angiography (FA) and enhanced depth-imaging (EDI) optical coherence tomography (OCT) (EDI-OCT) and (ii) correlate these variations with visual acuity. Methods : This study was a retrospective observational case series of patients with diabetic retinopathy (DR) and DME. The study groups comprised 77 DR patients ( n = 87), all of whom underwent color fundus photography, FA, and OCT on the same day. The control group comprised 25 age-matched healthy individuals ( n = 50 eyes). CT was measured by manual segmentation (EDI-OCT built-in ...

      Read Full Article
    4. Anterior lens capsule and epithelium thickness measurements using spectral-domain optical coherence tomography

      Anterior lens capsule and epithelium thickness measurements using spectral-domain optical coherence tomography

      Background To investigate the anterior lens capsule and epithelium thickness (defined as anterior lens capsular complex: ALCC) in normal Chinese subjects using spectral-domian optical coherence tomography (SD-OCT) and examine the factors that may influence the ALCC, such as age, gender, pupil diameter (PD) and signal strength index (SSI). Methods A prospective observational case series. One-hundred-thirty-four normal subjects (134 eyes) were included. The ALCCs were determined manually via SD-OCT. Using the pupil center as a reference position, the central ALCC (CALCC), nasal 1-mm ALCC (NALCC), temporal 1-mm ALCC (TALCC) and PD were measured manually. Results The mean CALCC, NALCC and TALCC ...

      Read Full Article
    5. Comparison of spectral-domain optical coherence tomography for intra-retinal layers thickness ...

      Comparison of spectral-domain optical coherence tomography for intra-retinal layers thickness ...

      Purpose To compare intra-retinal layer thickness measurements between eyes with no or mild diabetic retinopathy (DR) and age-matched controls using Spectralis spectral-domain optical coherence tomography (SD-OCT). Methods Cross-sectional observational analysis study. High-resolution macular volume scans (30° * 25°) were obtained for 133 type 2 diabetes mellitus (T2DM) patients with no DR, 42 T2DM patients with mild DR and 115 healthy controls. The mean thickness was measured in all 9 Early Treatment Diabetic Retinopathy Study (ETDRS) sectors for 8 separate layers, inner retinal layer (IRL), outer retinal layer (ORL) and total retina (TR), after automated segmentation. The ETDRS grid consisted of three ...

      Read Full Article
    6. Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Aim The aim of the study was to investigate the interchangeability and reliability of macular perfusion measurements using optical coherence tomography angiography. Methods A prospective cross-sectional observational study. Healthy adult Chinese subjects were recruited. Macular perfusion parameters were automatically analysed by software included in a spectral-domain optical coherence tomography system. The vessel density (VD) of the whole, parafovea, superior-hemi, inferior-hemi, fovea, temporal, superior, nasal and inferior quadrants as well as the foveal avascular zone (FAZ) and choroidal capillary VD (CCVD) were quantified. Results A total of 51 eyes in 27 subjects were included (8 men and 19 women, mean age ...

      Read Full Article
    7. Macular Thickness in Myopia: An OCT Study of Young Chinese Patients

      Macular Thickness in Myopia: An OCT Study of Young Chinese Patients

      Purposes : To investigate macular thickness (MT) in young myopic Chinese patients using Spectralis optical coherence tomography (OCT) and to assess its association with gender, axial length (AL), spherical equivalent (SE), and intraocular pressure (IOP). Methods : Included in this study were 133 myopic Chinese patients, aged 18–30 years. All underwent complete ophthalmic examinations and Spectralis OCT. Inner, central, and outer foveal regions of the macula were measured. Results : The central fovea was the thinnest of the three macular regions (mean thickness, 250.1 ± 15.3 μm). Women had consistently thinner MTs than did men, except in the outer superior and ...

      Read Full Article
    8. Macular Thickness Assessed with Optical Coherence Tomography in Young Chinese Myopic Patients

      Macular Thickness Assessed with Optical Coherence Tomography in Young Chinese Myopic Patients

      Purpose. To evaluate the variations in macular thickness in young Chinese myopic persons and the association with axial length (AL), spherical equivalence refraction (SE), age, intraocular pressure, and sex. Methods. In total, 133 young Chinese myopic subjects between 18 and 30 years of age were selected. The macular thickness was assessed using third-generation optical coherence tomography. AL, intraocular pressure, and SE were also measured. Results. The mean central foveal thickness was   µ m. The macula was consistently thinner in women than in men. Central foveal thickness had a significant positive correlation with AL and a negative correlation with SE. In the ...

      Read Full Article
    9. Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis

      Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis

      Aims To investigate swept-source optical coherence tomography (OCT) angiography in the optic nerve head (ONH) and parafoveal regions in patients with multiple sclerosis (MS). Methods Fifty-two MS eyes and 21 healthy control (HC) eyes were included. There were two MS subgroups: 38 MS eyes without an optic neuritis (ON) history (MS −ON), and 14 MS eyes with an ON history (MS +ON). The OCT images were captured by high-speed 1050 nm swept-source OCT. The ONH flow index (FI) and parafoveal FI were quantified from OCT angiograms. Results The mean ONH FI was 0.160±0.010 for the HC group ...

      Read Full Article
    10. Mean central corneal thickness and corneal power measurements in pigmented and white rabbits using Visante optical coherence tomography and ATLAS corneal topography

      Mean central corneal thickness and corneal power measurements in pigmented and white rabbits using Visante optical coherence tomography and ATLAS corneal topography

      Objective To document central corneal thickness (CCT) and power measurements in pigmented and white rabbits using Visante anterior segment optical coherence tomography (AS-OCT) and the Humphrey ATLAS Corneal Topography System (HACTS). Animal studied Fourteen female rabbits (seven pigmented and seven white rabbits) were involved in this study. Procedure Twenty-eight eyes underwent AS-OCT and HACTS examination. Central corneal thickness, corneal power in the steepest and flattest meridians, astigmatism, pupil diameter (PD), and white-to-white (WTW) were calculated. Results The CCT was 390 ± 14.2 and 373 ± 7.2 μm for pigmented and white rabbits, respectively. The CCT values showed statistical difference between ...

      Read Full Article
    11. IOL Tilt and Decentration Estimation from 3 Dimensional Reconstruction of OCT Image

      IOL Tilt and Decentration Estimation from 3 Dimensional Reconstruction of OCT Image

      Purpose To evaluate intraocular lens (IOL) tilt and decentration by anterior segment optical coherence tomography (AS-OCT) using 3-dimensional (3D) reconstruction method. Design Prospective observational case series. Participants Thirty-nine patients (39 eyes) were included. Methods The IOL positions of all eyes were examined by AS-OCT. Images were obtained in 4 axes (0–180 degrees, 45–225 degrees, 90–270 degrees, and 135–315 degrees) using the quadrant-scan model. The cross-sectional images were analyzed with MATLAB software. Main Outcome Measures The angle (θ) between the reference pupillary plane and the IOL plane, the distances between the center points of the pupil circle and ...

      Read Full Article
    12. Comparison of central macular thickness between two spectral-domain optical coherence tomography in elderly non-mydriatic eyes

      Comparison of central macular thickness between two spectral-domain optical coherence tomography in elderly non-mydriatic eyes

      AIM: To compare central macular thickness (CMT) measurements obtained by two spectral-domain optical coherence tomography (SD-OCT) exams, and to evaluate measurement reproducibility and agreement between these two exams, and to investigate the relationship between CMT and possible influencing factors such as age, sex, eye (OD/OS), and operators in elderly non-mydriatic eyes. METHODS: Seventy-two normal subjects were included. Every subject underwent CMT measurement twice using one of two SD-OCT (OSE-2000, Moptim, Shenzhen, China & 3-D OCT-1000, Topcon, Tokyo, Japan) instruments respectively where we randomly chose one eye in each patient for the test; these exams were performed by two operators over ...

      Read Full Article
    13. Normal corneal thickness measurements in pigmented rabbits using spectral-domain anterior segment optical coherence tomography

      Normal corneal thickness measurements in pigmented rabbits using spectral-domain anterior segment optical coherence tomography

      Objective To document the thickness of the central cornea in pigmented rabbits using spectral-domain anterior segment optical coherence tomography (AS-OCT). Animals studied Seventeen pigmented rabbits (6 male, 11 female, both eyes) were involved in this study. Procedures Thirty-four eyes from healthy pigmented rabbits underwent a complete ophthalmologic examination, including AS-OCT. Eight radial scans, 6 mm in length and centered on the cornea, were obtained using the AS-OCT. Corneal thickness was automatically calculated using pachymetry software. Measurements were displayed as the mean and standard deviation for each of the 17 regions defined by the software. The regions were the center (1 ...

      Read Full Article
    14. Evaluating subconjunctival bleb function after trabeculectomy using slit-lamp optical coherence tomography and ultrasound biomicroscopy

      Background The existing classifications for evaluating glaucoma filtering blebs rely mostly on external bleb characteristics and the postoperative control of intraocular pressure (IOP). Internal bleb structures are not carefully observed. This study aimed to analyze and compare glaucoma filtering bleb morphology using slit-lamp-adapted optical coherence tomography (SL-OCT) and ultrasound biomicroscopy (UBM), and to classify blebs according to results and intraocular pressure. Methods We followed 29 eyes of 21 male patients and 40 eyes of 32 female patients who underwent glaucoma filtering surgery in Sixth People’s Hospital of Shanghai, between 2002 and 2006. The blebs were imaged using SL-OCT and ...
      Read Full Article
    1-14 of 14
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. Topics in the News

    1. (8 articles) Shanghai Jiao Tong University
    2. (2 articles) Center for Ophthalmic Optics and Lasers
    3. (2 articles) Oregon Health & Science University
    4. (2 articles) David Huang
    5. (2 articles) Yali Jia
    6. (2 articles) Topcon Medical Systems
    7. (2 articles) Carl Zeiss Meditec
    8. (2 articles) Heidelberg Engineering
    9. (1 articles) Nanjing University of Science and Technology
    10. (1 articles) Shenzhen Moptim Imaging Technique Co.
  3. Popular Articles

  4. Picture Gallery

    Normal corneal thickness measurements in pigmented rabbits using spectral-domain anterior segment optical coherence tomography Comparison of central macular thickness between two spectral-domain optical coherence tomography in elderly non-mydriatic eyes IOL Tilt and Decentration Estimation from 3 Dimensional Reconstruction of OCT Image Mean central corneal thickness and corneal power measurements in pigmented and white rabbits using Visante optical coherence tomography and ATLAS corneal topography Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis Macular Thickness Assessed with Optical Coherence Tomography in Young Chinese Myopic Patients Macular Thickness in Myopia: An OCT Study of Young Chinese Patients Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography Comparison of spectral-domain optical coherence tomography for intra-retinal layers thickness ... In vivo dynamic characterization of the human tympanic membrane using pneumatic optical coherence tomography Negative Vessel Remodeling in Stargardt Disease Quantified with Volume-Rendered Optical Coherence Tomography Angiography Spectral Domain – Optical Coherence Tomography findings in Triple-A Syndrome – A case series from Pakistan