Close Message
None

Articles from Robert W. Knighton

1-9 of 9
Categories:
Applications: Art, Bronchoscopy, Cardiology, Dentistry, Dermatology, Developmental Biology, Endoscopy, Glucose, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Urology
Business News: Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
Technology: Broadband Sources, Doppler, Probes, Tunable Sources
Miscellaneous: Jobs & Studentships, Student Theses, Textbooks

  1. Characteristics of Optic Nerve Head Drusen on Optical Coherence Tomography Images

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Feb 5 2010) Ophthalmology

    BACKGROUND AND OBJECTIVE To describe the characteristics of optic nerve head drusen in optical coherence tomography (OCT) images. PATIENTS AND METHODS Cross-sectional images of the optic nerve were obtained in seven patients with optic nerve head drusen with Stratus and spectral-domain OCT (Carl Zeiss Meditec, Dublin, CA). These were compared to optic disc photographs, autofluorescence, and echography images. For comparison, these tests were performed on four patients with papilledema and three patients with small optic discs. RESULTS Optic nerve head drusen typically elevated the disc surface and appeared as an optically empty cavity, sometimes with a perceptible reflection from the ... (Read Full Article)

    Comment on Article Mentions:   Zeiss Stratus OCT   University of Miami   Carl Zeiss Meditec

  2. Spectral Domain Optical Coherence Tomographic Imaging of Geographic Atrophy

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Apr 6 2009) Ophthalmology

    BACKGROUND AND OBJECTIVE To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using fundus autofluorescence (FAF). PATIENTS AND METHODS Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. RESULTS GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference ... (Read Full Article)

    Comment on Article Mentions:   Carl Zeiss Meditec   Philip J. Rosenfeld   University of Miami

  3. Spectral Domain Optical Coherence Tomography for Proliferative Diabetic Retinopathy With Subhyaloid Hemorrhage

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Dec 11 2008) Ophthalmology

    A prototype 6-µm axial resolution spectral domain optical coherence tomography (SD-OCT) device was used to image the retina of a patient with uncontrolled diabetes mellitus who had proliferative diabetic retinopathy with subhyaloid hemorrhage. A raster scan pattern with 128 B-scans covering a 6 × 6 × 2-mm volume of the retina was obtained. SD-... (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   Keck School of Medicine   University of Miami

  4. Macular Spectral-domain Optical Coherence Tomography in Patients with X-linked Retinoschisis

    Explore Article BJO Online (Nov 18 2008) Ophthalmology

    Purpose: The purpose of this study is to evaluate macular anatomy in patients with X-linked retinoschisis (XLRS) using spectral-domain OCT (SD-OCT). Methods: Consecutive observational case series. Clinical features were obtained through retrospective chart review. Only eyes without prior surgical interventions and those scanned with SD-OCT were included. The OCT images were analyzed. Results: Fourteen eyes of 7 males with XLRS scanned with SD-OCT, age 5 to 45 years, were identified. On clinical examination, stellate spoke-like cystic maculopathy was present in 9 eyes, and an atrophic foveal lesion in 5 eyes. SD-OCT revealed cystoid spaces accounting for retinal splitting in the ... (Read Full Article)

    Comment on Article Mentions:   Keck School of Medicine   Carmen A. Puliafito   University of Miami

  5. Macular Thickness Measurements in Normal Eyes Using Spectral Domain Optical Coherence Tomography

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Sep 10 2008) Ophthalmology

    BACKGROUND AND OBJECTIVE Knowledge of the macular thickness in a normal population is important for the evaluation of pathological macular change. The purpose of this study was to define and measure macular thickness in normal eyes using spectral domain optical coherence tomography (OCT). PATIENTS AND METHODS Fifty eyes from 50 normal subjects (29 men and 21 women, aged 22 to 68 years) were scanned with a prototype Cirrus HD-OCT system (5 µm axial resolution) (Carl Zeiss Meditec, Inc.). The proprietary Cirrus segmentation algorithm was used to produce retinal thickness maps, which were then averaged over 9 regions defined by a ... (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   Keck School of Medicine   University of Miami

  6. Calibration of Fundus Images Using Spectral Domain Optical Coherence Tomography

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Sep 10 2008) Ophthalmology

    BACKGROUND AND OBJECTIVE Measurements performed on fundus images using current software are not accurate. Accurate measurements can be obtained only by calibrating a fundus camera using measurements between fixed retinal landmarks, such as the dimensions of the optic nerve, or by relying on a calibrated model eye provided by a reading center. However, calibrated spectral domain OCT (SD-OCT) could offer a convenient alternative method for the calibration of any fundus image. PATIENTS AND METHODS The ability to measure exact distances on SD-OCT fundus images was tested by measuring the distance between the center of the fovea and the optic nerve. ... (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   Keck School of Medicine   University of Miami

  7. Spectral Domain Optical Coherence Tomographic Imaging of Geographic Atrophy

    Explore Article Ophthalmic Surgery, Lasers and Imaging (Sep 10 2008) Ophthalmology

    BACKGROUND AND OBJECTIVE To compare images of geographic atrophy (GA) obtained using spectral domain optical coherence tomography (SD-OCT) with images obtained using auto fluorescence (FAF). PATIENTS AND METHODS Five eyes from patients with dry AMD were imaged using SD-OCT and FAF, and the size and shape of the GA were compared. RESULTS GA appears bright on SD-OCT compared with the surrounding areas with an intact retinal pigment epithelium because of increased reflectivity from the underlying choroid. SD-OCT and FAF both identified GA reproducibly, and measurement of the area of GA is comparable between the two methods with a mean difference ... (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   Keck School of Medicine   University of Miami

  8. Corneal birefringence mapped by scanning laser polarimetry

    Explore Article opticsinfobase.org (Aug 21 2008) Ophthalmology

    Corneal birefringence mapped by scanning laser polarimetry Corneal birefringence affects polarization-sensitive optical measurements of the eye. Recent literature supports the idea that corneal birefringence is biaxial, although with some disagreement among reports and without considering corneas with very low values of central retardance. This study ... [Opt. Express 16, 13738-13751 (2008)] (Read Full Article)

    Comment on Article Mentions:   Carl Zeiss Meditec

  9. Enhanced optical coherence tomography for anatomical mapping

    Explore Article PatFT » Page 1 of 1 (Nov 27 2007) Ophthalmology , Patents

    A system, method and apparatus for anatomical mapping utilizing optical coherence tomography. In the present invention, 3-dimensional fundus intensity imagery can be acquired from a scanning of light back-reflected from an eye. The scanning can include spectral domain scanning, as an example. A fundus intensity image can be acquired in real-time. The 3-dimensional data set can be reduced to generate an anatomical mapping, such as an edema mapping and a thickness mapping. Optionally, a partial fundus intensity image can be produced from the scanning of the eye to generate an en face view of the retinal structure of the eye ... (Read Full Article)

    Comment on Article Mentions:   Carmen A. Puliafito   Giovanni Gregori   University of Miami

1-9 of 9
HomeAll ArticlesProfilesQuotesComments Login Register Powered by HiveFire