1. Articles from M. Tariq Bhatti

    1-9 of 9
    1. Spectral Domain-Optical Coherence Tomography of the Vitreopapillary Interface in Acute Non-Arteritic Anterior Ischemic Optic Neuropathy

      Spectral Domain-Optical Coherence Tomography of the Vitreopapillary Interface in Acute Non-Arteritic Anterior Ischemic Optic Neuropathy

      Purpose To use spectral domain-optical coherence tomography (SD-OCT) to assess whether epipapillary vitreous traction from evolving posterior vitreous detachment (PVD) is mechanistically involved in the pathogenesis of non-arteritic anterior ischemic optic neuropathy (NAION). Design Retrospective cohort study. Methods.Setting Single academic center. Patient or study population Eighty eyes in 74 subjects presenting within 2 weeks of symptom onset of NAION. Intervention or observation procedures SD-OCT imaging of the optic nerve head, macula, and peripapillary retinal nerve fiber layer (pRNFL) were reviewed for PVD and vitreopapillary traction (VPT). Main Outcome Measures Prevalence and incidence of PVD and VPT, logMAR best-corrected visual ...

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      Mentions: Duke University
    2. Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema

      Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema

      Purpose To determine whether the diameter of Bruch’s membrane opening (BMO) can distinguish mild papilledema from pseudopapilledema using optical coherence tomography (OCT). Methods The medical records of pediatric patients with pseudopapilledma due to optic nerve head (ONH) drusen, patients with papilledema, and normal control subjects were reviewed retrospectively. All eyes underwent OCT imaging of the BMO and retinal nerve fiber layer (RNFL). Transverse horizontal diameter of the BMO and papillary height were measured. Mean BMO, papillary height, and RNFL were compared and receiver operating characteristic (ROC) curves were used to calculate the area under the curve (AUC) and determine ...

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    3. Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema

      Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema

      Purpose To determine whether the diameter of Bruch’s membrane opening (BMO) can distinguish mild papilledema from pseudopapilledema using optical coherence tomography (OCT). Methods The medical records of pediatric patients with pseudopapilledma due to optic nerve head (ONH) drusen, patients with papilledema, and normal control subjects were reviewed retrospectively. All eyes underwent OCT imaging of the BMO and retinal nerve fiber layer (RNFL). Transverse horizontal diameter of the BMO and papillary height were measured. Mean BMO, papillary height, and RNFL were compared and receiver operating characteristic (ROC) curves were used to calculate the area under the curve (AUC) and determine ...

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    4. Emerging Applications of Optical Coherence Tomography in Pediatric Optic Neuropathies

      Emerging Applications of Optical Coherence Tomography in Pediatric Optic Neuropathies

      Limited cooperation and attention span often lead to poorly reliable assessments of visual acuity and visual fields in children, making diagnosis and monitoring of pediatric optic neuropathies challenging. As a noninvasive imaging modality, optical coherence tomography (OCT) could offer particular utility in this patient population. OCT provides high-resolution characterization of the optic nerve head, peripapillary retinal nerve fiber layer, and cellular layers of the macula, all of which can be used to assess the severity of optic nerve disease qualitatively and quantitatively. Application of OCT to pediatric patients has been limited by technical factors and lack of pediatric normative databases ...

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      Mentions: Duke University
    5. Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema

      Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema

      New Spectralis (Heidelberg, Germany) segmentation software allows automatic quantitation of the thickness of each macular layer. We evaluated the role of Spectralis spectral domain optical coherence tomography (SD-OCT) segmentation in children during acute papilledema to predict the subsequent development of optic atrophy.

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    6. The application of optical coherence tomography in neurologic diseases

      The application of optical coherence tomography in neurologic diseases

      Optical coherence tomography (OCT) has become an increasingly popular tool in various disciplines of medicine, particularly ophthalmology and neurology. It is an imaging technology that has revolutionized the practice of ophthalmology by providing anatomic detail of pathologic changes in the retina and optic nerve. OCT is routinely used as an ancillary test that can aid in the diagnosis and monitoring of neuro-ophthalmic diseases such as papilledema, optic neuritis, and neuroretinitis. OCT measurements have also been shown to predict visual prognosis in compressive optic neuropathies. Changes in OCT measurements have been used to study the course of particular neurologic diseases such ...

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    7. Retinal Atrophy in Eyes With Resolved Papilledema Detected by Optical Coherence Tomography

      Retinal Atrophy in Eyes With Resolved Papilledema Detected by Optical Coherence Tomography

      Background: To apply automated spectral domain optical coherence tomography (SD-OCT) segmentation to eyes with resolving papilledema. Methods: Ninety-four patients with idiopathic intracranial hypertension seen at the Duke Eye Center neuro-ophthalmology clinic between November 2010 and October 2011 were reviewed. Excluded were eyes with papilledema with Frisen grade >2, other optic neuropathies or retinopathies, and those that did not have SD-OCT imaging. The remaining 43 patients were split into 2 groups: non-atrophic papilledema and atrophic papilledema. Automated SD-OCT segmentation was performed on patients with non-atrophic papilledema and age-matched controls for each of the 9 regions of the Early Treatment Diabetic Retinopathy ...

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    8. Differentiating Glaucomatous from Non-Glaucomatous Optic Nerve Cupping by Optical Coherence Tomography

      Differentiating Glaucomatous from Non-Glaucomatous Optic Nerve Cupping by Optical Coherence Tomography
      Abstract: Background: In clinical practice, the differentiation of glaucomatous from non-glaucomatous cupping can be difficult, even for experienced observers. The purpose of this study was to evaluate the role of optical coherence tomography (OCT) in differentiating glaucomatous from non-glaucomatous optic nerve cupping in a cross-sectional pilot study. Methods: Eleven consecutive patients presenting to the Duke Eye Center from September 2007 to July 2008 with nonglaucomatous optic nerve cupping and 12 patients with glaucomatous optic nerve cupping were identified. All patients underwent Stratus® OCT imaging: fast macular map, fast retinal nerve fiber layer (RNFL) 3.4 thickness, and fast optic disc ...
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    9. Optical coherence tomography in the evaluation of neurofibromatosis type 1 subjects with optic pathway gliomas

      Introduction: Neurofibromatosis type 1 (NF1) is the most common hereditary neurocutaneous disorder and associated with optic pathway gliomas (OPGs) in ∼15% of affected children. OPGs can be difficult to detect on clinical inspection, often requiring neuro-imaging. Optical coherence tomography (OCT) has been shown to be a useful diagnostic technology in several pediatric eye conditions including glaucoma and idiopathic intracranial hypertension. Our prospective case-series evaluates OCT findings of retinal nerve fiber layer (RNFL) loss from optic atrophy due to OPGs in pediatric NF1 subjects.
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    1-9 of 9
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    1. (5 articles) Duke University
    2. (2 articles) Sharon F. Freedman
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    5. (1 articles) Jost B. Jonas
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    Differentiating Glaucomatous from Non-Glaucomatous Optic Nerve Cupping by Optical Coherence Tomography Retinal Atrophy in Eyes With Resolved Papilledema Detected by Optical Coherence Tomography The application of optical coherence tomography in neurologic diseases Optical coherence tomography macular segmentation as predictor for optic atrophy in children with acute papilledema Emerging Applications of Optical Coherence Tomography in Pediatric Optic Neuropathies Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema Bruch’s membrane opening on optical coherence tomography in pediatric papilledema and pseudopapilledema Spectral Domain-Optical Coherence Tomography of the Vitreopapillary Interface in Acute Non-Arteritic Anterior Ischemic Optic Neuropathy Optical imaging techniques could offer non-invasive method to measure swelling within the brain, new study finds Using Optical Coherence Tomography as a Surrogate of Measurements of Intracranial Pressure in Idiopathic Intracranial Hypertension Endoscopic imaging in inflammatory bowel disease: current developments and emerging strategies 2D Ultrasonic Array-based Optical Coherence Elastography