1. Articles from Kazuhiro Sasaki

    1-4 of 4
    1. Three-dimensional retinal and choroidal capillary imaging by power Doppler optical coherence angiography with adaptive optics

      Three-dimensional retinal and choroidal capillary imaging by power Doppler optical coherence angiography with adaptive optics

      Retinal and choroidal vascular imaging is a key to the better understanding and diagnosis of eye diseases. To achieve comprehensive three-dimensional capillary imaging, we used an enhanced vascular imaging technique, so called adaptive optics optical coherence angiography (AO-OCA). AO-OCA enables in vivo high-resolution and high-contrast micro-vascular imaging by detecting Doppler frequency shifts. Using this technique, the retinal and choroidal vasculatures of healthy subjects were imaged. The results show that both intensity and Doppler power images have sufficient contrast to discriminate almost all vasculatures from the static tissue. However, the choriocapillaris, pre-arterioles, and post-venules in the Sattler layer were more contrasted ...

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    2. Extended depth of focus adaptive optics spectral domain optical coherence tomography

      Extended depth of focus adaptive optics spectral domain optical coherence tomography
      We present an adaptive optics spectral domain optical coherence tomography (AO-SDOCT) with a long focal range by active phase modulation of the pupil. A long focal range is achieved by introducing AO-controlled third-order spherical aberration (SA). The property of SA and its effects on focal range are investigated in detail using the Huygens-Fresnel principle, beam profile measurement and OCT imaging of a phantom. The results indicate that the focal range is extended by applying SA, and the direction of extension can be controlled by the sign of applied SA. Finally, we demonstrated in vivo human retinal imaging by altering the ...
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    3. Simultaneous high-resolution retinal imaging and high-penetration choroidal imaging by one-micrometer adaptive optics optical coherence tomography

      Simultaneous high-resolution retinal imaging and high-penetration choroidal imaging by one-micrometer adaptive optics optical coherence tomography
      Adaptive optics optical coherence tomography (AO-OCT) provides three-dimensional high-isotropic-resolution retinal images in vivo. We developed AO-OCT with a 1.03-μm probing beam and demonstrated high-penetration, high-resolution retinal imaging. Axial scans are acquired with a speed of 47,000 lines/s. AO closed loop is configured with a single deformable mirror. Seven eyes of 7 normal subjects were examined. Signal enhancement was found for all subjects. A rippled interface between nerve fiber layer and ganglion cell layer, boundary between ganglion cell layer and inner plexiform layer, and chorioscleral interface were identified. Simultaneous high-resolution and high-penetration choroidal imaging may be useful for ...
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    4. Adaptive optics spectral domain optical coherence tomography with one-micrometer light source

      Adaptive optics spectral domain optical coherence tomography with one-micrometer light source
      Adaptive optics spectral domain optical coherence tomography (AO SD-OCT) has provided three-dimensional high isotropic resolution retinal images in vivo. In order to enhance the image quality of deep region of the eye, the alternative wavelength of 1-µm has been used for ophthalmic OCT. This study aims to develop AO SD-OCT with one-micrometer probe and demonstrated high penetration and high resolution retinal imaging. A broadband 1-µm SLD light source (Suplerlum) have the center wavelength of 1.03 µm and the spectral bandwidth of 106 nm. Axial scans were obtained by an InGaAs line scan camera with the speed of 47,000 ...
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    1-4 of 4
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  2. Topics in the News

    1. (4 articles) University of Tsukuba
    2. (4 articles) Shuichi Makita
    3. (4 articles) Yoshiaki Yasuno
    4. (1 articles) Oregon Health & Science University
    5. (1 articles) Masahiro Yamanari
    6. (1 articles) Barry Cense
    7. (1 articles) Imagine Eyes
    8. (1 articles) Eric A. Swanson
    9. (1 articles) Canon Medical Systems
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    Adaptive optics spectral domain optical coherence tomography with one-micrometer light source Simultaneous high-resolution retinal imaging and high-penetration choroidal imaging by one-micrometer adaptive optics optical coherence tomography Extended depth of focus adaptive optics spectral domain optical coherence tomography Three-dimensional retinal and choroidal capillary imaging by power Doppler optical coherence angiography with adaptive optics Changes in Amblyopia Using Optical Coherence Tomography Integrated optical system with photonic integrated circuit including coherent optical receiver and optical phased array Surface emitting laser, information acquiring apparatus, imaging apparatus, laser array, and method of manufacturing surface emitting laser Automatic choroidal segmentation in OCT images using supervised deep learning methods Optoretinography: optical measurements of human cone and rod photoreceptor responses to light Nodular skin lesions: correlation of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) features OCT and Ophthalmology in the Age of Artificial Intelligence, Tuesday Oct 8, 2019 1:00P EDT Compensation for the Influence of Fluctuations in the Distance to the Object During Noncontact Probing in Spectral Domain Optical Coherence Tomography