1. Articles from Desmond Adler

    1-12 of 12
    1. Optical buffer-based apparatus for increasing light source repetition rate

      Optical buffer-based apparatus for increasing light source repetition rate

      In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the first optical coupler and a second end in optical communication with a second mirror, wherein light entering the first arm of the first optical coupler leaves the first arm of ...

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    2. Multimodal imaging system, apparatus, and methods

      Multimodal imaging system, apparatus, and methods

      In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L1 and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In ...

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    3. Optical coherence tomography control systems and methods

      Optical coherence tomography control systems and methods

      In part, the invention relates to methods, devices, and systems suitable for controlling a light source. The light source is configured for use in a data collection system such as an optical coherence tomography system. The light source can be controlled with a drive waveform. Linearizing and symmetrizing parameters of the light source such as forward and backward scan durations is achieved using a suitable drive waveform. Phase, amplitude, and other parameters for different harmonics of a fundamental wave can be identified that improve operating parameters such as the duty cycle and peak frequency matching between scans. The fundamental wave ...

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    4. Optical buffering methods, apparatus, and systems for increasing the repetition rate of tunable light sources

      Optical buffering methods, apparatus, and systems for increasing the repetition rate of tunable light sources

      In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the first optical coupler and a second end in optical communication with a second mirror, wherein light entering the first arm of the first optical coupler leaves the first arm of ...

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    5. Vascular Data Processing And Image Registration Systems, Methods, And Apparatuses

      Vascular Data Processing And Image Registration Systems, Methods, And Apparatuses

      In part, the invention relates to processing, tracking and registering angiography images and elements in such images relative to images from an intravascular imaging modality such as, for example, optical coherence tomography (OCT). Registration between such imaging modalities is facilitated by tracking of a marker of the intravascular imaging probe performed on the angiography images obtained during a pullback. Further, detecting and tracking vessel centerlines is used to perform a continuous registration between OCT and angiography images in one embodiment.

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    6. Optical Coherence Tomography Control Systems And Methods

      Optical Coherence Tomography Control Systems And Methods

      In part, the invention relates to methods, devices, and systems suitable for controlling a light source (7). The light source is configured for use in a data collection system such as an optical coherence tomography system (5). The light source (7) can be controlled with a drive waveform (10, 22, 55, 70). Linearizing and symmetrizing parameters of the light source (7) such as forward (35, 60, 75) and backward (33, 63, 77) scan durations is achieved using a suitable drive waveform (22, 55, 70).

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    7. Miniature optical elements for fiber-optic beam shaping

      Miniature optical elements for fiber-optic beam shaping

      In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that ...

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    8. Methods, systems, and devices for timing control in electromagnetic radiation sources

      Methods, systems, and devices for timing control in electromagnetic radiation sources

      In one embodiment, the invention relates to systems, methods and devices for improving the operation of an electromagnetic radiation source or component thereof. In one embodiment, the source is a laser source. A Fourier domain mode locked laser can be used in various embodiments. The sources described herein can be used in an optical coherence tomography (OCT) system such as a frequency domain OCT system. In one embodiment, laser coherence length is increased by compensating for dispersion. A frequency shifter can also be used in one embodiment to compensate for a tunable filter induced Doppler shift.

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    9. Bench-to-bedside success: intravascular optical coherence tomography

      Bench-to-bedside success: intravascular optical coherence tomography

      After more than 20 years of academic research and industrial development, optical coherence tomography has found a new home in the interventional cardiology suite. If one were to ask a physician to describe an ideal medical imaging technology, the resulting wish list might include high resolution, high sensitivity, and rapid acquisition speeds, all delivered at low cost with minimal risk to the patient in a platform that is simple and easy to use. Neglect any one of these requirements, and the technology in question might at best be relegated to a niche research role. Since its invention in 1991 by ...

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    10. Miniature Optical Elements For Fiber-Optic Beam Shaping

      Miniature Optical Elements For Fiber-Optic Beam Shaping
      In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that ...
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    11. Miniature Optical Elements For Fiber-Optic Beam Shaping

      Miniature Optical Elements For Fiber-Optic Beam Shaping
      In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that ...
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    12. Clinical studies of frequency domain optical coherence tomography in the coronary arteries: the first 200 patients

      Clinical studies of frequency domain optical coherence tomography in the coronary arteries: the first 200 patients
      We report clinical study results of three-dimensional (3D) in vivo imaging of human coronary arteries using frequency domain optical coherence tomography (FD-OCT). At the time of this report, over 2000 patients in over 10 countries have been imaged using FD-OCT systems and disposable fiberoptic catheters developed by LightLab Imaging Inc. The first commercial versions of the systems were introduced in Europe in May 2009. The system operates at 50,000 axial lines/s, performing a 50 mm spiral pullback in 2.5 seconds with a rotational frame rate of 100 Hz. The commercial system employs a proprietary micro-cavity swept laser ...
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    1-12 of 12
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  2. Topics in the News

    1. (12 articles) Desmond C. Adler
    2. (12 articles) Abbot
    3. (7 articles) Joseph M. Schmitt
    4. (4 articles) Chris L. Petersen
    5. (2 articles) Lightlab C7 XR OCT Imaging System
    6. (1 articles) Massachusetts Institute of Technology
    7. (1 articles) James G. Fujimoto
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    Clinical studies of frequency domain optical coherence tomography in the coronary arteries: the first 200 patients Miniature Optical Elements For Fiber-Optic Beam Shaping Miniature Optical Elements For Fiber-Optic Beam Shaping Bench-to-bedside success: intravascular optical coherence tomography Miniature optical elements for fiber-optic beam shaping Methods, systems, and devices for timing control in electromagnetic radiation sources Optical Coherence Tomography Control Systems And Methods Vascular Data Processing And Image Registration Systems, Methods, And Apparatuses Optical buffering methods, apparatus, and systems for increasing the repetition rate of tunable light sources Optical coherence tomography control systems and methods Competency-Based Assessment of Interventional Cardiology Fellows’ Abilities in Intracoronary Physiology and Imaging Real-time, non-contact, cellular imaging and angiography of human cornea and limbus with common-path Full-field/SD OCT