1. Articles from Shulian Wu

    1-11 of 11
    1. Depth-independent internal fingerprint based on optical coherence tomography

      Depth-independent internal fingerprint based on optical coherence tomography

      Optical coherence tomography (OCT) was used for imaging three-dimensional fingerprint to overcome the effects of different skin states and fake fingerprint. However, the OCT-based fingerprint features depend on the depth of fingertip skin which is still challenging for biometric recognition and encryption. In this work, we presented a new approach of maximum intensity projection (MIP) image of the epidermal-dermal junction (DEJ) to extract the internal fingerprint that is independent of the depth of fingertip skin. To begin with, the surface and DEJ were segmented based on the deep learning algorithm. Then the internal fingerprint was extracted by the MIP image ...

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    2. Quantitative analysis of vascular changes during photoimmunotherapy using speckle variance optical coherence tomography (SV-OCT)

      Quantitative analysis of vascular changes during photoimmunotherapy using speckle variance optical coherence tomography (SV-OCT)

      Near-infrared (NIR) photoimmunotherapy (NIR-PIT) is an emerging cancer therapy based on a monoclonal antibody and phthalocyanine dye conjugate. Direct tumor necrosis and immunogenic cell death occur during NIR irradiation. However, the alteration of tumor blood vessels and blood volume inside the blood vessels induced by the NIR-PIT process is still unknown. In our study, a speckle variance (SV) algorithm combined with optical coherence tomography (OCT) technology was applied to monitor the change of blood vessels and the alterations of the blood volume inside the blood vessels during and after NIR-PIT treatment. Vascular density and the measurable diameter of the lumen ...

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    3. Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo

      Orthogonal‐polarization‐gating optical coherence tomography for human sweat ducts in vivo

      We propose an orthogonal‐polarization‐gating optical coherence tomography (OPGOCT) for human sweat ducts in vivo . OPG‐OCT is composed of the orthogonal linearly polarized light of a sample arm individually interfering with orthogonal linearly polarized lights of the reference arms, where OPG‐OCT induces two images, one reflecting the projection intensity and the other the horizontal linear diattenuation (HLD). The results demonstrate that OPG‐OCT projection intensity could improve the image quality of sweat ducts. HLD also clearly illustrates the spiral shape of the sweat ducts. Finally, sweat ducts in intensity image are segmented by employing convolutional neural networks ...

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    4. Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo

      Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo

      We propose an orthogonal-polarization-gating optical coherence tomography (OPGOCT) for human sweat ducts in vivo. OPG-OCT is composed of the orthogonal linearly polarized light of a sample arm individually interfering with orthogonal linearly polarized lights of the reference arms, where OPG-OCT induces two images, one reflecting the projection intensity and the other the horizontal linear diattenuation (HLD). The results demonstrate that OPG-OCT projection intensity could improve the image quality of sweat ducts. HLD also clearly illustrates the spiral shape of the sweat ducts. Finally, sweat ducts in intensity image are segmented by employing convolutional neural networks (CNN). The proportions of left-handed ...

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    5. Observation and analysis on skin cancer induced by UVB irradiation using optical coherence tomography

      Observation and analysis on skin cancer induced by UVB irradiation using optical coherence tomography

      Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are the prevalent skin cancers, which have a quite high incidence in the white race. In recent years, however, their incidences have been increasing in the yellow race, resulting in a great threat to the public health. According to researches, chronics UVB irradiation (280nm~320nm) is the major culprit of skin cancer in humans. In our study, the model of UVB induced skin cancer was established firstly. Optical coherence tomography (OCT) combined with the histopathology was exploited to monitor the morphologic and histological changes of the process of UVB induced skin ...

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    6. Experimental research and observation of the skin response of mice with a second-degree scald duringirradiation by a CO 2 laser

      Experimental research and observation of the skin response of mice with a second-degree scald duringirradiation by a CO 2 laser

      Second-degree scalding is a common dermatological injury. Inappropriate treatment methods in clinical practice always produce scarring, and can lead to skin cancer and other complications in the longer term. In this study optical coherence tomography (OCT) combined with a skin detector was used to monitor the response of second-degree scalded skin tissue irradiated by a CO2 laser. The process of treatment of second-degree scalding was systematically studied from the perspective of tissue optics. The OCT signal intensity was stronger within the whole recovery period in the experimental group undergoing CO2 laser treatment, and the attenuation coefficient (μt) returned ...

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    7. Optical features for chronological aging and photoaging skin by optical coherence tomography

      Optical features for chronological aging and photoaging skin by optical coherence tomography

      Abstract  The characteristics of skins in different aging processes were obtained by optical coherence tomography (OCT) single scattering model, and their optical parameters were analyzed quantitatively. Significant differences were found in epidermis thickness and attenuation coefficients in chronological aging skins and photonaging skins. These parameters can be served as indicators of skin type as well as the progress of aging. These results are valuable to the study of aging skin, and they could further help to understand the mechanism of aging.

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    8. Optical characters and texture maps of skin and the aging mechanism by use of multiphoton microscopy and optical coherence tomography

      Optical characters and texture maps of skin and the aging mechanism by use of multiphoton microscopy and optical coherence tomography

      Cutaneous aging is a complicated biological process affecting different constituents of skin, which can be divided into two types: the chronological aging and the photo-aging. The two cutaneous aging processes often co-exist accompanying with each other. The effects are often overlapped including changes in epithelium and dermis. The degeneration of collagen is a major factor in dermal alteration with aging. In this study, multiphoton microscopy (MPM) with its high resolution imaging and optical coherence tomography (OCT) with its depth resolved imaging were used to study the anti-aging dermatology in vivo. It was attempted to make the optical parameter and texture ...

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    9. Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography

      Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography
      It is imperative to evaluate the tissue wound healing response after laser irradiation so as to develop effective devices for this clinical indication, and evaluate the thermal damage degree to take appropriate treatment. In our research, we prepare 6 white rat (approximately 2 months old, weight :28±2g). Each rat was injected intraperitoneally a single dose of 2% pentobarbital sodium. After the rat was anesthetized, the two side of the rats' back were denuded and antisepsised a standardized. An Er:YAG laser (2940nm, 2.5J/cm2, single spot, 4 times) was irradiated on rat skin in vivo, and the skin ...
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    10. Monitoring collagen remodeling on opto-thermal response of photoaged skin irradiated by Er:YAG laser with optical coherence tomography

      Monitoring collagen remodeling on opto-thermal response of photoaged skin irradiated by Er:YAG laser with optical coherence tomography

      The Optical Coherence Tomography technology was used to perform noninvasive cross-sectional imaging of internal structures in photoaged mouse skin irradiated by Er:YAG laser. The mice were irradiated chronically with a steady dose of ultraviolet irradiation. Various laser light doses were irradiated on the back skins of the photoaged mouse. An OCT was used to observe the process of the collagen remodeling in dermis. The relationship between optical characteristic parameter such as attenuation coefficient and light dose was discovered. The total attenuation coefficient increased when the light dose increased. Our findings showed that Er:YAG laser could be used for ...

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    11. Combined optical coherence tomography based on the extended Huygens-Fresnel principle and histology of mouse skin

      Combined optical coherence tomography based on the extended Huygens-Fresnel principle and histology of mouse skin

      Noninvasive measurement technique to obtain tissue optical properties such as the scattering coefficient µs and the anisotropy factor g using optical coherence tomography (OCT) scattering model which based on the Extended Huygens-Fresnel principle is developed in our paper. Older and younger mouse-skin are as animal model to compare its scattering coefficient µs and the anisotropy factor g, the outcome shows that scattering coefficient µs is increased with the age of mouse-skin. Furthermore, we have made age's mouse-skin into H.E stain slices; the result of its morphology is consistent with the OCT imaging and OCT-EHF principle. All of that ...

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    1-11 of 11
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  2. Topics in the News

    1. (7 articles) Fujian Normal University
    2. (1 articles) University of Maryland
    3. (1 articles) Photop Technologies
    4. (1 articles) National Institutes of Health
    5. (1 articles) University of Tübingen
    6. (1 articles) Stanford University
    7. (1 articles) Johns Hopkins University
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    Combined optical coherence tomography based on the extended Huygens-Fresnel principle and histology of mouse skin Monitoring the process of tissue healing of rat skin in vivo after laser irradiation based on optical coherence tomography Monitoring collagen remodeling on opto-thermal response of photoaged skin irradiated by Er:YAG laser with optical coherence tomography Optical characters and texture maps of skin and the aging mechanism by use of multiphoton microscopy and optical coherence tomography Optical features for chronological aging and photoaging skin by optical coherence tomography Experimental research and observation of the skin response of mice with a second-degree scald duringirradiation by a CO 2 laser Observation and analysis on skin cancer induced by UVB irradiation using optical coherence tomography Orthogonal-polarization-gating optical coherence tomography for human sweat ducts in vivo Quantitative analysis of vascular changes during photoimmunotherapy using speckle variance optical coherence tomography (SV-OCT) Depth-independent internal fingerprint based on optical coherence tomography Optical coherence tomography findings in patients with transfusion-dependent β-thalassemia Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea