1. Articles from nozomi nishimura

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    1. Computed optical coherence microscopy of mouse brain ex vivo

      Computed optical coherence microscopy of mouse brain ex vivo

      The compromise between lateral resolution and usable imaging depth range is a bottleneck for optical coherence tomography (OCT). Existing solutions for optical coherence microscopy (OCM) suffer from either large data size and long acquisition time or a nonideal point spread function. We present volumetric OCM of mouse brain ex vivo with a large depth coverage by leveraging computational adaptive optics (CAO) to significantly reduce the number of OCM volumes that need to be acquired with a Gaussian beam focused at different depths. We demonstrate volumetric reconstruction of ex-vivo mouse brain with lateral resolution of 2.2  μm, axial resolution of ...

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    2. Device and method for inducing vascular injury and/or blockage in an animal model

      Ultrashort laser pulses are used to induce photodisruptive breakdown in vasculature in an animal to controllably produce hemorrhage, thrombosis or breach of the blood-brain barrier in individual, specifically-targeted blood vessels. Damage is limited to the targeted vessels such that neighboring vessels exhibit no signs of vascular damage, including vessels directly above and directly below the targeted vessel. Ultrashort laser pulses of lower energy are also used to observe and quantify the baseline and altered states of blood flow. Observation and measurement may be performed by TPLSM, OCT or other known techniques, providing a real-time, in vivo model for the dynamics ...
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    1-2 of 2
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    1. (1 articles) Cornell University
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    Computed optical coherence microscopy of mouse brain ex vivo The Structural and Comparative Analysis of Intravitreal Dexamethasone Implant (Ozurdex) and Anti-VEGF Injection in Branched Retinal Vein Occlusion Patients by Optical Coherence Tomography Angiography Images Quantitation Vascular Responses to First-Generation Sirolimus-Eluting Stents and Bare-Metal Stents Beyond 10 Years Ocular Parameters Evaluation in Relation to the Refractive Error using Optical Coherence Topography Micro Optical Coherence Tomography for Coronary Imaging Macular Vessel Density in Diabetic Retinopathy Patients: How Can We Accurately Measure and What Can It Tell Us? Systems and methods for long working distance optical coherence tomography (OCT) Evaluation of the retinal nerve fiber layer with optic coherence tomography in patients with alcohol use disorder Predictive OCTA Biomarkers After Endoscopic Endonasal Pituitary Surgery NEI joins call for standardization of ophthalmic imaging devices Repeatability of Optical Coherence Tomography Angiography Measurements in Patients with Retinal Vein Occlusion Retinal Vascularization Analysis on Optical Coherence Tomography Angiography before and after Intraretinal or Subretinal Fluid Resorption in Exudative Age-Related Macular Degeneration: A Pilot Study