1. Articles from Donald T. Tan

    1-6 of 6
    1. Refractive lenticule extraction flap and stromal bed morphology assessment with anterior segment optical coherence tomography

      Refractive lenticule extraction flap and stromal bed morphology assessment with anterior segment optical coherence tomography

      Purpose To evaluate the flap and stromal bed after refractive lenticule extraction using optical coherence tomography (OCT). Setting Singapore National Eye Centre, Singapore. Design Longitudinal case series. Methods Horizontal scans (RTVue) were taken preoperatively and after refractive lenticule extraction. Two procedures were performed: femtosecond lenticule extraction and small-incision femtosecond lenticule extraction. Flap and bed thicknesses were measured at the center (0.0 mm) and 1.5 mm and 3.0 mm to either side. Results At 1 week, the mean flap at 0.0 mm was borderline thicker (P=.056) and at +3.0 mm significantly thicker after femtosecond lenticule ...

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    2. Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty

      Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty

      Background To assess repeatability of the Zhongshan Assessment Program (ZAP) software measurement of Anterior Segment Optical Coherence Tomography (ASOCT) images and correlate with graft trephine diameter following Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) Methods Retrospectively evaluated interventional case series. 121 consecutive eyes undergoing DSAEK over a 26 month period underwent ASOCT imaging 1 month after their surgery. ASOCT images were processed using ZAP software which measured the graft and cornea parameters including anterior and posterior graft arc length and cord length, posterior cornea arc length (PCAL) and anterior chamber width. Results The graft measurements showed good repeatability on ASOCT using ...

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    3. Intraoperative use of spectral-domain optical coherence tomography during Descemet’s stripping automated endothelial keratoplasty

      Intraoperative use of spectral-domain optical coherence tomography during Descemet’s stripping automated endothelial keratoplasty

      Purpose: To evaluate the intraoperative changes in the donor lenticule, recipient cornea, and the reduction of interface fluid thickness during Descemet’s stripping and automated endothelial keratoplasty with EndoGlide™ (Angiotech Pharmaceuticals Inc, Vancouver, Canada) donor insertion, using intraoperative spectral-domain optical coherence tomography. Methods: Prospective observational case series of patients underwent Descemet’s stripping and automated endothelial keratoplasty using the EndoGlide inserter. Spectral-domain optical coherence tomography (iVue; Optovue Inc, Fremont, CA) with a handheld probe was used to image the cornea and anterior chamber. Standardized software was used to measure interface fluid gap, host cornea, and donor lenticule thicknesses during the ...

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    4. Reproducibility of Cornea Measurements in Anterior Segment OCT images of Normal Eyes and Eyes with Bullous Keratopathy Analyzed with the Zhongshan Assessment Program (ZAP)

      Reproducibility of Cornea Measurements in Anterior Segment OCT images of Normal Eyes and Eyes with Bullous Keratopathy Analyzed with the Zhongshan Assessment Program (ZAP)

      Purpose: To determine the interobserver and intraobserver measurement reproducibility of cornea parameters of both normal eyes and eyes with bullous keratopathy obtained with the Zhongshan Assessment Program (ZAP, Guangzhou, China) on Anterior segment optical coherence tomography (AS-OCT, Visante; Carl Zeiss Meditec, Dublin, CA) images. Methods: Comparative study of 24 healthy volunteers and 25 subjects with bullous keratopathy (BK). AS-OCT images were independently analyzed by two examiners. Parameters examined: anterior chamber depth (ACD), central corneal thickness (CCT), posterior corneal curvature (PCC) and posterior corneal arc length (PCAL). Interobserver and intraobserver reproducibility of the above parameters was calculated in terms of limits ...

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    5. Laser in situ keratomileusis flap measurements: Comparison between observers and between spectral-domain and time-domain anterior segment optical coherence tomography

      Laser in situ keratomileusis flap measurements: Comparison between observers and between spectral-domain and time-domain anterior segment optical coherence tomography

      Purpose To evaluate the between-observer (interobserver) and between-instrument (intraobserver) variability in flap thickness measurements after laser in situ keratomileusis (LASIK) using spectral-domain and time-domain anterior segment optical coherence tomography (AS-OCT). Setting Singapore National Eye Centre. Design Evaluation of diagnostic test or technology. Methods Two independent masked observers measured flap thickness 1 month after LASIK using spectral-domain (RTVue) or time-domain (Visante) AS-OCT. The measurements were taken at central (0.0 mm), −1.5 mm, and +1.5 mm locations. Measurements were repeated to assess between-instrument variability. Results There was no statistically significant difference in mean flap thickness between the 2 observers ...

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    6. Biometry of the Cornea and Anterior Chamber in Chinese Eyes: an Anterior Segment Optical Coherence Tomography Study

      Purpose: To investigate the normative data of corneal and anterior segment biometric parameters in Chinese adults and their associations for use in preoperative assessment for corneal and anterior segment surgery. Methods: This cross-sectional, population based study included 750 subjects aged 50 years. The subjects underwent an ophthalmic examination including imaging using anterior segment optical coherence tomography (AS-OCT). Dimensions were subsequently measured with the Zhongshan Assessment Program (ZAP). We also include posterior corneal arc length (PCAL), a novel parameter defined as the arc distance between scleral spurs on the posterior border of the cornea. Correlations with age, gender, height, weight, body ...

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    1-6 of 6
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    Laser in situ keratomileusis flap measurements: Comparison between observers and between spectral-domain and time-domain anterior segment optical coherence tomography Reproducibility of Cornea Measurements in Anterior Segment OCT images of Normal Eyes and Eyes with Bullous Keratopathy Analyzed with the Zhongshan Assessment Program (ZAP) Intraoperative use of spectral-domain optical coherence tomography during Descemet’s stripping automated endothelial keratoplasty Correlation of anterior segment optical coherence tomography measurements with graft trephine diameter following descemet stripping automated endothelial keratoplasty Refractive lenticule extraction flap and stromal bed morphology assessment with anterior segment optical coherence tomography Evaluating Retinal and Choroidal Perfusion Changes After Ocular Massage of Healthy Eyes Using Optical Coherence Tomography Angiography Dermal Epidermal Junction Detection for Full-Field Optical Coherence Tomography Data of Human Skin by Deep Learning OctNET: A Lightweight CNN for Retinal Disease Classification from Optical Coherence Tomography Images The Association between Tear Film Thickness as Measured with OCT and Symptoms and Signs of Dry Eye Disease: A Pooled Analysis of 6 Clinical Trials Optical Coherence Tomography Utility in Management of Coronary Artery Injury due to Blunt Chest Trauma Optical coherence tomography angiography analysis of the retina in patients recovered from COVID-19: A case-control study Optical Coherence Tomography to Predict Plaque Progression: A Glimpse Into the Crystal Ball?