1. Articles from Simon K. Law

    1-4 of 4
    1. Prediction of Glaucoma Progression with Structural Parameters: Comparison of Optical Coherence Tomography and Clinical Disc Parameters

      Prediction of Glaucoma Progression with Structural Parameters: Comparison of Optical Coherence Tomography and Clinical Disc Parameters

      Purpose To test the hypothesis that baseline optical coherence tomography (OCT) measures predict visual field (VF) progression in a cohort of patients with suspected or established glaucoma and compare their performance to semiquantitative optic disc measures. Design Observational cohort study. Methods Setting: Academic institution. Study Population One-hundred seventy-one eyes of 95 patients with good-quality baseline retinal nerve fiber layer (RNFL) and macular OCT images and disc photographs with >2 years of follow-up and ≥5 VFs. Observation Procedures Baseline macular and RNFL OCT measures and cup-to-disc ratio and disc damage likelihood score. Main Outcome Measures Prediction of glaucomatous visual field deterioration ...

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    2. Structure-Function Relationships between Spectral-Domain OCT and Standard Achromatic Perimetry

      Structure-Function Relationships between Spectral-Domain OCT and Standard Achromatic Perimetry

      Purpose: To explore structure-function relationships in early glaucoma with spectral-domain optical coherence tomography (SD-OCT) and standard achromatic perimetry. Methods: One hundred thirty-six eyes of 97 patients with suspected or early glaucoma were enrolled from the clinical database at UCLA's Glaucoma Division. All patients had good-quality peripapillary retinal nerve fiber layer (RNFL)/optic disc measurements (Optic Disc Cube 200x200, Cirrus HD-OCT) and a reliable 24-2 SITA-Standard Humphrey visual field (VF) within a 6-month period. Correlations of global and sectoral RNFL thickness and rim area (RA) measurements with corresponding global and regional VF sensitivities (both in logarithmic [dB] and 1/Lambert ...

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    3. Characterization of Retinal Nerve Fiber Layer in Nonglaucomatous Eyes With Tilted Discs

      Clinical assessment of the optic disc and nerve fiber layer (NFL) is an important method to diagnose and monitor the progress of glaucomatous optic neuropathy but is often difficult in eyes with tilted discs.1-3 Clinically, there are 2 orientations of tilting of the optic disc: temporal and inferior1 (Figure 1). Optical coherence tomography (OCT) demonstrates an acceptable diagnostic ability for glaucoma by comparing an individual patient's NFL thickness profile with those in a normative database.4-6 The purpose of this study is to characterize the NFL of nonglaucomatous eyes with tilted discs using OCT.

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    4. Optic disc image in advanced age-related macular degeneration

      Evaluation of the optic disc and retinal nerve fiber layer is an essential part of the ophthalmic examination for diagnosis and for monitoring the progress of various types of optic neuropathy. Qualitative evaluation with stereoscopic optic disc photography is the traditional clinical method for the documentation of the optic disc appearance for serial comparisons. Recently, many imaging techniques have become available for optic disc and retinal nerve fiber layer evaluation. Confocal scanning laser ophthalmoscopy, scanning laser polarimetry and optical coherence tomography are currently the most widely used techniques by the ophthalmic community. These techniques have been reported to be reproducible ...
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      Mentions: UCLA
    1-4 of 4
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  2. Topics in the News

    1. (2 articles) David Geffen School of Medicine
    2. (2 articles) UCLA
    3. (2 articles) Joseph Caprioli
    4. (1 articles) Carl Zeiss Meditec
    5. (1 articles) Zeiss Cirrus HD-OCT
    6. (1 articles) National University of Singapore
    7. (1 articles) University of Lübeck
    8. (1 articles) Singapore Eye Research Institute
    9. (1 articles) Imperial College London
    10. (1 articles) University College London
    11. (1 articles) Leiden University
    12. (1 articles) Baylor College of Medicine
    13. (1 articles) Gereon Hüttmann
    14. (1 articles) Patrick W. Serruys
    15. (1 articles) Irina V. Larina
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