1. Articles from robert r. alfano

    1-10 of 10
    1. Method and apparatus for producing supercontinuum light for medical and biological applications

      Method and apparatus for producing supercontinuum light for medical and biological applications

      A method and an apparatus are provided for producing SuperContinuum (SC) light for medical and biological applications is provided. Pulses are focused from a laser system into at least one of a pressurized cell and one or more fibers. A pump pulse is converted into the SC light at a specified rate of repetition. The SC light is applied at the specified rate of repetition to tissue for medical and biological applications.

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      Mentions: Robert R. Alfano
    2. New Shine on Old Gems

      New Shine on Old Gems
      Trivalent chromium-doped LIGO/LISO offers the widest lasing bandwidth in the telecommunications windows. Newly developed Cr3+ laser crystals called LIGO and LISO, developed at the Institute for Ultrafast Spectroscopy and Lasers (IUSL) at City College of the City University of New York, extend the family of ruby and alexandrite lasers operating in the near-infrared from 1150 to 1620 nm for possible 6-fs-pulse-generation and telecommunications applications. Combined with Ti:sapphire crystals, pulses as short as approximately 2 fs could be produced. In addition, the broad spectral operation of these materials is suitable for generating 6-fs-pulse optical coherence tomography, condensed matter physics ...
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    3. The Supercontinuum Laser Source: Fundamentals with Updated References (Book)

      The Supercontinuum Laser Source: Fundamentals with Updated References (Book)
      Photonics and nonlinear optics are important areas of science, engineering and technology. One of the most important ultrafast nonlinear optical processes is the supercontinuum (SC) – the production of intense white light pulses covering: uv, visible, NIR, MIR, and IR. It is produced using ultrashort laser pulses (ps/fs) to produce the ultrabroad band of frequencies. This book covers the fundamental principles and surveys research of current thinkers and experts in the field with updated references of the key breakthroughs over the past decade and a half. The application of SC are time-resolved pump-SC probe absorption and excitation spectroscopy for chemistry ...
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    4. Imaging systems and methods to improve backscattering imaging using circular polarization memory

      An optical technique to improve the imaging of a target inside suspensions of scattering particles includes the illumination of the scattering particles with circularly polarized light. The backscattered light from the host medium preserves the helicity of incident light, while the backscattered light reflected from the target is predominated with light of opposite helicity. Based on the observed helicity difference in the emerging light that originated at the target and that backscattered from the medium, the present optical technique improves the image contrast using circular polarization. This approach makes use of polarization memory which leads to the reflected light from ...
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    5. Method and apparatus for producing a multiple optical channel source from a supercontinuum generator for WDM communication

      A system and method for producing a multiple optical channel source (MOCS). The method includes producing the SC in a medium using at least one femto-second or pico-second optical input pump pulse; splitting input pump pulse or resultant output SC pulse(s) into a plurality of collinear pulses; applying a time delay .tau. between the least one of input pump pulse or SC pulses; and producing a MOCS by the spectral interference of the plurality of SC pulses. The system includes a laser producing femto-second or pico-second pump pulses, a medium with a high value of the .chi..sup.(3 ...
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    6. System and method for performing selected optical measurements utilizing a position changeable aperture

      A system and method for performing selected optical measurements on a sample is provided utilizing an optical coherence domain reflectometer which includes a diffraction grating. A broad band light source produces light having a short coherence length. A beamsplitter splits the light into a signal beam and a reference beam. A reference mirror is disposed to receive the reference beam. A lens brings the signal beam to focus on the sample. A diffraction grating receives reflections from the sample and from the reference mirror, the reflections being incident on the diffraction grating with respect to said diffraction grating normal such ...
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    7. Sub-surface imaging under paints and coatings using early light spectroscopy

      A system for non-destructively imaging surfaces through a coating, in accordance with the present invention, includes a near-infrared (NIR) light source for illuminating a coated surface. A detector is positioned in an operative relationship with the NIR light source to receive light backscattered from the coated surface and from the coating. A gating device is positioned in an operative relationship with the detector to selectively permit light to pass to the detector to measure optical characteristics of the backscattered light such that determinations of a state of a surface below the coating is determined based on the optical characteristics of ...
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    8. Performing selected optical measurements with optical coherence domain reflectometry

      A system and method for performing selected optical measurements on a sample is provided utilizing an optical coherence domain reflectometer which includes a diffraction grating. A broad band light source produces light having a short coherence length. A beamsplitter splits the light into a signal beam and a reference beam. A reference mirror is disposed to receive the reference beam. A lens brings the signal beam to focus on the sample. A diffraction grating receives reflections from the sample and from the reference mirror, the reflections being incident on the diffraction grating with respect to said diffraction grating normal such ...
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    9. Non-linear optical tomography of turbid media

      An apparatus utilizing non-linear optical signals for use in constructing a three-dimensional tomographic map of an in vivo biological tissue for medical disease detection purposes. In one embodiment, said apparatus comprises a stage for supporting the in vivo biological tissue; a laser for illuminating the in vivo biological tissue with a focused beam of laser light, the light emerging from the in vivo biological tissue comprising fundamental light, harmonic wave light, and fluorescence due to multi-photon excitation; a filter for selectively passing only at least one of the harmonic wave light and the fluorescence; one or more detectors for individually ...
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    10. Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents

      A method and system for imaging an object in a turbid medium. According to one embodiment, the method involves (a) making the object luminescent by adding to the object a contrast agent of the type that emits at least partially polarized light when appropriately excited with polarized radiation; (b) exciting the luminescent object through the turbid medium with polarized radiation so as to cause luminescent light to be emitted from the luminescent object, the luminescent light initially being at least partially polarized; (c) after the luminescent light has emerged from the turbid medium, the luminescent light consisting of a ballistic ...

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    1-10 of 10
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    1. (10 articles) Robert R. Alfano
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    The Supercontinuum Laser Source: Fundamentals with Updated References (Book) New Shine on Old Gems Method and apparatus for producing supercontinuum light for medical and biological applications Combining Deep Learning With Optical Coherence Tomography Imaging to Determine Scalp Hair and Follicle Counts Efficacy and Safety of Laser‐Assisted Combination Chemotherapy: An Explorative Imaging‐Guided Treatment With 5‐Fluorouracil and Cisplatin for Basal Cell Carcinoma A NOVEL FINDING OF HYPERREFLECTIVE MATERIAL IN THE SILICONE-RETINA INTERFACE: An Optical Coherence Tomographic and Histopathological Study SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY, FLUORESCEIN ANGIOGRAPHY, AND INDOCYANINE GREEN ANGIOGRAPHY COMPARISONS REVISITED: Using a Novel Deep-Learning-Assisted Approach for Image Registration AUTOMATED RETINAL LAYER SEGMENTATION AND THEIR THICKNESS PROFILES IN HEALTHY SUBJECTS: A Comparison of 55° Wide-field and Conventional 30° Spectral Domain-Optical Coherence Tomography RELATIONSHIP BETWEEN PREOPERATIVE FOVEAL MICROSTRUCTURE AND VISUAL ACUITY IN MACULA-OFF RHEGMATOGENOUS RETINAL DETACHMENT: Imaging Analysis by Swept Source Optical Coherence Tomography Vitreous Seeding in Retinocytoma: Importance of Optical Coherence Tomography Utility of Spectral-Domain Optical Coherence Tomography in Differentiating Papilledema From Pseudopapilledema: A Prospective Longitudinal Study Visualizing and quantifying cutaneous microvascular reactivity in humans using optical coherence tomography: Impaired dilator function in diabetes