1. Articles from brian wong

    1-7 of 7
    1. Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Purpose Studies examining the anterior chamber angle and angle closure disease often compare quantitative angle information obtained using anterior segment optical coherence tomography (ASOCT) with one of several ordinal scales derived using gonioscopy. We test the assumption that the ordinal gonioscopic angle grades have equal step sizes and can be analysed using metric statistics. Methods The medical records of 214 consecutive patients who were referred for assessment of the anterior chamber angle were prospectively examined using gonioscopy and ASOCT (Spectralis Optical Coherence Tomography, OCT, www.heidelbergengineering.com ). Anterior chamber angle parameters (angle opening distance, AOD, and trabecular‐iris space area ...

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    2. Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling.

      Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling.

      We understand now that sleep of sufficient length and quality is required for good health. This is particularly true for infants and children, who have the added physiologic task of growth and development, as compared to their adult counterparts. Sleep-related breathing disorders (SRBDs) are common in childhood and if unrecognized and not treated can result in significant morbidity. For example, children with obstructive sleep apnea (OSA) can exhibit behavioral, mood, and learning difficulties. If left untreated, alterations in the function of the autonomic nervous system and a chronic inflammatory state result, contributing to the risk of heart disease, stroke, glucose ...

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    3. Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system

      Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system
      Vocal fold vibration is vital in voice production and the correct pitch of speech. University of California Irvine researchers have developed a high speed functional optical coherence tomography (OCT) system with a center wavelength of 1050 nm and an imaging speed of 100,000 A-lines per second and demonstrated imaging of the vibration of an ex-vivo swine vocal fold. High quality vocal fold images during vibration was demonstrated at an imaging speed of 100 frames per second. Functional information, such as vibration frequency and vibration amplitude, was obtained by analyzing the tissue surface during vibration. The axial direction velocity distribution ...
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    4. Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT

      Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT
      Vocal fold vibration is vital in voice production and the correct pitch of speech. We have developed a high speed functional optical coherence tomography (OCT) system with a center wavelength of 1050 nm and an imaging speed of 100,000 A-lines per second. We imaged the vibration of an ex-vivo swine vocal fold. At an imaging speed of 100 frames per second, we demonstrated high quality vocal fold images during vibration. Functional information, such as vibration frequency and vibration amplitude, was obtained by analyzing the tissue surface during vibration. The axial direction velocity distribution in the cross-sectional images of the ...
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    5. Emerging applications for OCT in the head and neck

      Emerging applications for OCT in the head and neck
      Objectives To describe the current and promising new applications of the Optical Coherence Tomography (OCT) as a helpful tool when imaging the different sites in the head and neck. Using the OCT Niris system, which is the first commercially available OCT device for applications outside the field of ophthalmology. Methods We obtained OCT images of normal, benign, premalignant and malignant lesions in different areas of the head and neck. The OCT imaging system has a tissue penetration depth of approximately 1-2mm, a scanning range of 2mm and a spatial depth resolution of approximately 10-20μm. Imaging was performed using a flexible ...
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    6. Imaging of the Pediatric Airway Using Optical Coherence Tomography

      Objectives: Optical coherence tomography (OCT) is an imaging modality that uses a broadband light source to produce high‐resolution cross‐sectional images in living tissue (8–20 μm). A prospective study of normal, benign, and pathologic tissues in the pediatric airway was conducted to assess the utility of OCT technology in characterizing the microanatomy of the pediatric upper aerodigestive tract in vivo. Study Design: Prospective clinical trial. Materials and Methods: Fifteen patients from 1 to 17 years of age underwent surgical endoscopy and OCT for various airway disorders. OCT imaging was performed at a frame rate of 1 Hz using ...

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    7. In vivo three-dimensional spectral domain endoscopic optical coherence tomography using a microelectromechanical system mirror

      Woonggyu Jung, Daniel T. McCormick, Yeh-Chan Ahn, Ali Sepehr, Matt Brenner, Brian Wong, Norman C. Tien, Zhongping Chen A biopsy is a well-known medical test used to evaluate tissue abnormality. Biopsy specimens are invasively taken from part of a lesion and visualized by microscope after chemical treatment. However, diagnosis by means of biopsy is not only variable due to depth and location of specimen but may also ... [Opt. Lett. 32, 3239-3241 (2007)]
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    1-7 of 7
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  2. Topics in the News

    1. (6 articles) UC Irvine
    2. (6 articles) Brian J. F. Wong
    3. (6 articles) Zhongping Chen
    4. (3 articles) Marc Rubinstein
    5. (2 articles) Allen I. Foulad
    6. (2 articles) Gangjun Liu
    7. (2 articles) Arya Saidi
    8. (2 articles) Wenjuan Qi
    9. (1 articles) James M. Ridgway
    10. (1 articles) Shuguang Guo
    11. (1 articles) University of Washington
    12. (1 articles) University of Melbourne
    13. (1 articles) Dresden University of Technology
    14. (1 articles) University of Bonn
    15. (1 articles) Julia Walther
    16. (1 articles) Frank G. Holz
    17. (1 articles) Edmund Koch
    18. (1 articles) Steffen Schmitz-Valckenberg
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    Emerging applications for OCT in the head and neck Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling. Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography Carotid Disease and Retinal Optical Coherence Tomography Angiography Parameters in Type 2 Diabetes: The Fremantle Diabetes Study Phase II Retinal Vascular Density on Optical Coherence Tomography Angiography and Age-related Central and Peripheral Hearing Loss in a Southern Italian Older Population Optical coherence tomography outcomes from SPRINT-MS, a multicenter, randomized, double-blind trial of ibudilast in progressive multiple sclerosis Microvascular alterations in children with optic disk drusen evaluated by optical coherence tomography angiography Polarization sensitive optical coherence tomography for imaging microvascular information within living tissue without polarization-induced artifacts Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images In Vivo Endoscopic Optical Coherence Tomography of the Healthy Human Oral Mucosa: Qualitative and Quantitative Image Analysis