1. Articles from brian wong

    1-7 of 7
    1. Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography

      Purpose Studies examining the anterior chamber angle and angle closure disease often compare quantitative angle information obtained using anterior segment optical coherence tomography (ASOCT) with one of several ordinal scales derived using gonioscopy. We test the assumption that the ordinal gonioscopic angle grades have equal step sizes and can be analysed using metric statistics. Methods The medical records of 214 consecutive patients who were referred for assessment of the anterior chamber angle were prospectively examined using gonioscopy and ASOCT (Spectralis Optical Coherence Tomography, OCT, www.heidelbergengineering.com ). Anterior chamber angle parameters (angle opening distance, AOD, and trabecular‐iris space area ...

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    2. Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling.

      Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling.

      We understand now that sleep of sufficient length and quality is required for good health. This is particularly true for infants and children, who have the added physiologic task of growth and development, as compared to their adult counterparts. Sleep-related breathing disorders (SRBDs) are common in childhood and if unrecognized and not treated can result in significant morbidity. For example, children with obstructive sleep apnea (OSA) can exhibit behavioral, mood, and learning difficulties. If left untreated, alterations in the function of the autonomic nervous system and a chronic inflammatory state result, contributing to the risk of heart disease, stroke, glucose ...

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      Mentions: UC Irvine
    3. Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system

      Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system
      Vocal fold vibration is vital in voice production and the correct pitch of speech. University of California Irvine researchers have developed a high speed functional optical coherence tomography (OCT) system with a center wavelength of 1050 nm and an imaging speed of 100,000 A-lines per second and demonstrated imaging of the vibration of an ex-vivo swine vocal fold. High quality vocal fold images during vibration was demonstrated at an imaging speed of 100 frames per second. Functional information, such as vibration frequency and vibration amplitude, was obtained by analyzing the tissue surface during vibration. The axial direction velocity distribution ...
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      Mentions: UC Irvine
    4. Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT

      Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT
      Vocal fold vibration is vital in voice production and the correct pitch of speech. We have developed a high speed functional optical coherence tomography (OCT) system with a center wavelength of 1050 nm and an imaging speed of 100,000 A-lines per second. We imaged the vibration of an ex-vivo swine vocal fold. At an imaging speed of 100 frames per second, we demonstrated high quality vocal fold images during vibration. Functional information, such as vibration frequency and vibration amplitude, was obtained by analyzing the tissue surface during vibration. The axial direction velocity distribution in the cross-sectional images of the ...
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      Mentions: UC Irvine
    5. Emerging applications for OCT in the head and neck

      Emerging applications for OCT in the head and neck
      Objectives To describe the current and promising new applications of the Optical Coherence Tomography (OCT) as a helpful tool when imaging the different sites in the head and neck. Using the OCT Niris system, which is the first commercially available OCT device for applications outside the field of ophthalmology. Methods We obtained OCT images of normal, benign, premalignant and malignant lesions in different areas of the head and neck. The OCT imaging system has a tissue penetration depth of approximately 1-2mm, a scanning range of 2mm and a spatial depth resolution of approximately 10-20μm. Imaging was performed using a flexible ...
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      Mentions: Imalux UC Irvine
    6. Imaging of the Pediatric Airway Using Optical Coherence Tomography

      Objectives: Optical coherence tomography (OCT) is an imaging modality that uses a broadband light source to produce high‐resolution cross‐sectional images in living tissue (8–20 μm). A prospective study of normal, benign, and pathologic tissues in the pediatric airway was conducted to assess the utility of OCT technology in characterizing the microanatomy of the pediatric upper aerodigestive tract in vivo. Study Design: Prospective clinical trial. Materials and Methods: Fifteen patients from 1 to 17 years of age underwent surgical endoscopy and OCT for various airway disorders. OCT imaging was performed at a frame rate of 1 Hz using ...

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      Mentions: UC Irvine
    7. In vivo three-dimensional spectral domain endoscopic optical coherence tomography using a microelectromechanical system mirror

      Woonggyu Jung, Daniel T. McCormick, Yeh-Chan Ahn, Ali Sepehr, Matt Brenner, Brian Wong, Norman C. Tien, Zhongping Chen A biopsy is a well-known medical test used to evaluate tissue abnormality. Biopsy specimens are invasively taken from part of a lesion and visualized by microscope after chemical treatment. However, diagnosis by means of biopsy is not only variable due to depth and location of specimen but may also ... [Opt. Lett. 32, 3239-3241 (2007)]
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      Mentions: UC Irvine
    1-7 of 7
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  2. Topics in the News

    1. (6 articles) UC Irvine
    2. (1 articles) University of New South Wales
    3. (1 articles) Imalux
    4. (1 articles) Capital Medical University
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    Emerging applications for OCT in the head and neck Imaging vibrating vocal folds with a high speed 1050 nm swept source OCT and ODT Feature Of The Week 12/18/11: UC Irvine Demonstrates Functional Imaging of Vibrating Vocal Folds with a High Speed OCT and ODT system Pediatric Sleep-Related Breathing Disorders: Advances in imaging and computational modeling. Assessment of angle closure spectrum disease as a continuum of change using gonioscopy and anterior segment optical coherence tomography Trojan-Horse Diameter-Reducible Nanotheranostics for Macroscopic/Microscopic Imaging-Monitored Chemo-Antiangiogenic Therapy Thickness of retinal pigment epithelium–Bruch’s membrane complex in adult Chinese using optical coherence tomography Interocular symmetry of optical coherence tomography parameters in healthy children and adolescents Fluorescein Leakage and Optical Coherence Tomography Angiography Features of Microaneurysms in Diabetic Retinopathy Cross-free in both lateral and axial directions Fourier-domain full-field optical coherence tomography Microperimetry, Humphrey field analyzer, and optical coherence tomography in detecting glaucoma: a comparative performance study Scanning optimization of an electrothermally-actuated MEMS mirror for applications in optical coherence tomography endoscopy