1. Articles from JoAnn Giaconi

    1-5 of 5
    1. Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements

      Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements

      Purpose To evaluate the performance of ganglion cell layer/inner plexiform layer (GCL/IPL) measurements with spectral-domain optical coherence tomography (Cirrus HD-OCT) for detection of early glaucoma and to compare results to retinal nerve fiber layer (RNFL) measurements. Design Cross-sectional prospective diagnostic study. Methods We enrolled 99 subjects, including 59 eyes with glaucoma (47 subjects) (mean deviation >−6.0 dB) and 91 normal eyes (52 subjects). Patients underwent biometry and peripapillary and macular OCT imaging. Performance of the GCL/IPL and RNFL algorithms was evaluated with area under receiver operating characteristic curves (AUC), likelihood ratios, and sensitivities/specificities adjusting for ...

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    2. Measurement of the Optic Disc Vertical Tilt Angle With Spectral-Domain Optical Coherence Tomography and Influencing Factors

      Measurement of the Optic Disc Vertical Tilt Angle With Spectral-Domain Optical Coherence Tomography and Influencing Factors

      Purpose To report a novel method for measuring the vertical tilt angle of the optic nerve (ON) head and to investigate the associated factors. Design Cross-sectional diagnostic study. Methods One hundred and twelve normal, glaucomatous, and glaucoma suspect eyes (99 patients) were enrolled in this study. Subjects underwent a full eye examination, biometry, and spectral-domain optical coherence tomography (SDOCT). The vertical tilt angle was measured on high-resolution cross-sectional SDOCT images passing through the ON head and foveal centers using the inner edges of the Bruch membrane opening as the reference plane. The correlation between the vertical tilt angle with the ...

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    3. Measurement of Optic Disc Size and Rim Area with Spectral-Domain OCT and Scanning Laser Ophthalmoscopy

      Measurement of Optic Disc Size and Rim Area with Spectral-Domain OCT and Scanning Laser Ophthalmoscopy

      Purpose: To compare optic disc and neuroretinal rim area measurements from spectral-domain optical coherence tomography (SD-OCT) to those from confocal scanning laser ophthalmoscopy. Methods: Seventy-one eyes from 43 normal subjects or suspected/definite glaucoma patients were prospectively enrolled. All subjects had biometry with the IOLMaster and disc/retinal nerve fiber layer (RNFL) imaging with Cirrus SD-OCT (Optic Disc Cube 200x200) and Heidelberg Retina Tomograph (HRT). Keratometry-corrected (K-corrected) HRT measurements and uncorrected Cirrus disc and rim areas and disc measurements corrected for eye magnification with Bennett's formula (AL-corrected) along with 30-degree sectoral rim areas, vertical cup-to-disc ratio (VCDR), and cup ...

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    4. Structure-Function Relationships between Spectral-Domain OCT and Standard Achromatic Perimetry

      Structure-Function Relationships between Spectral-Domain OCT and Standard Achromatic Perimetry

      Purpose: To explore structure-function relationships in early glaucoma with spectral-domain optical coherence tomography (SD-OCT) and standard achromatic perimetry. Methods: One hundred thirty-six eyes of 97 patients with suspected or early glaucoma were enrolled from the clinical database at UCLA's Glaucoma Division. All patients had good-quality peripapillary retinal nerve fiber layer (RNFL)/optic disc measurements (Optic Disc Cube 200x200, Cirrus HD-OCT) and a reliable 24-2 SITA-Standard Humphrey visual field (VF) within a 6-month period. Correlations of global and sectoral RNFL thickness and rim area (RA) measurements with corresponding global and regional VF sensitivities (both in logarithmic [dB] and 1/Lambert ...

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    5. Characterization of Retinal Nerve Fiber Layer in Nonglaucomatous Eyes With Tilted Discs

      Clinical assessment of the optic disc and nerve fiber layer (NFL) is an important method to diagnose and monitor the progress of glaucomatous optic neuropathy but is often difficult in eyes with tilted discs.1-3 Clinically, there are 2 orientations of tilting of the optic disc: temporal and inferior1 (Figure 1). Optical coherence tomography (OCT) demonstrates an acceptable diagnostic ability for glaucoma by comparing an individual patient's NFL thickness profile with those in a normative database.4-6 The purpose of this study is to characterize the NFL of nonglaucomatous eyes with tilted discs using OCT.

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    1-5 of 5
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  2. Topics in the News

    1. (5 articles) David Geffen School of Medicine
    2. (5 articles) Joseph Caprioli
    3. (3 articles) UCLA
    4. (3 articles) Zeiss Cirrus HD-OCT
    5. (2 articles) Carl Zeiss Meditec
    6. (1 articles) University College London
    7. (1 articles) Medical University of Vienna
    8. (1 articles) Kings College London
    9. (1 articles) Stefan G. Sacu
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    Structure-Function Relationships between Spectral-Domain OCT and Standard Achromatic Perimetry Measurement of Optic Disc Size and Rim Area with Spectral-Domain OCT and Scanning Laser Ophthalmoscopy Measurement of the Optic Disc Vertical Tilt Angle With Spectral-Domain Optical Coherence Tomography and Influencing Factors Macular Ganglion Cell/Inner Plexiform Layer Measurements by Spectral Domain Optical Coherence Tomography for Detection of Early Glaucoma and Comparison to Retinal Nerve Fiber Layer Measurements Deep iterative vessel segmentation in OCT angiography Subretinal Drusenoid Deposits and Photoreceptor Loss Detecting Global and Local Progression of Geographic Atrophy by SD-OCT Imaging Ultra-high-resolution SD-OCM imaging with a compact polarization-aligned 840 nm broadband combined-SLED source Sparse Domain Gaussianization for Multi-variate Statistical Modeling of Retinal OCT Images Optical reflectance contrast of micro- and nano-structures revealed with intravital micro-OCT (Thesis) In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography–based tumor characterization Morphological changes in intraretinal microvascular abnormalities after anti-VEGF therapy visualized on optical coherence tomography angiography SD-OCT peripapillary nerve fibre layer and ganglion cell complex parameters in glaucoma: principal component analysis