1. Articles from X. Yang

    1-3 of 3
    1. Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method

      Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method

      Fiber-optic probes for sensing and biomedical imaging applications such as optical coherence tomography (OCT) frequently employ sections of graded-index (GRIN) fiber to re-focus the diverging light from the delivery fiber. Such GRIN fiber microlenses often possess aberrations that cause significant distortions of the focused output beam. Current design methods based on ABCD matrix transformations of Gaussian beams cannot model such effects and are therefore inadequate for the analysis and design of high-performance probes that require diffraction-limited output beams. We demonstrate use of the beam propagation method (BPM) to analyze beam distortion in GRINlensed fibers resulting from index profiles that exhibit ...

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    2. 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      Evaluation of degradation in the structure of skeletal muscle is important for the assessment or diagnosis of many myopathies, such as Duchenne muscular dystrophy. Histological analysis is the gold standard to evaluate such degradation but requires excision and fixation of the tissue. This is undesirably invasive in patients and precludes longitudinal study of disease progression in patients or animal models. Optical coherence tomography (OCT) is a high-resolution (∼10μm) imaging modality capable of visualising muscle structure and the morphological changes in muscular dystrophy. However, because of the limited image penetration of OCT (∼2mm), previous studies have been restricted to imaging ...

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    3. Ultrathin side-viewing needle probe for optical coherence tomography

      Ultrathin side-viewing needle probe for optical coherence tomography

      We present the smallest reported side-viewing needle probe for optical coherence tomography (OCT). Design, fabrication, optical characterization, and initial application of a 30-gauge (outer diameter 0.31 mm) needle probe are demonstrated. Extreme miniaturization is achieved by using a simple all-fiber probe design incorporating an angle-polished and reflection-coated fiber-tip beam deflector. When inserted into biological tissue, aqueous interstitial fluids reduce the probe’s inherent astigmatism ratio to 1.8, resulting in a working distance of 300 μm and a depth-of-field of 550 μm with beam diameters below 30 μm. The needle probe was interfaced with an 840 nm spectral-domain OCT ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) University of Western Australia
    2. (3 articles) Dirk Lorenser
    3. (3 articles) David D. Sampson
    4. (2 articles) Xiaojie Yang
    5. (2 articles) Rodney W. Kirk
    6. (1 articles) Robert A. McLaughlin
    7. (1 articles) Yonsei University
    8. (1 articles) Imperial College London
    9. (1 articles) University of Manchester
    10. (1 articles) Chang Gung University
    11. (1 articles) Erasmus University
    12. (1 articles) Chan Yun Kim
    13. (1 articles) Patrick W. Serruys
    14. (1 articles) Yusuke Fujino
    15. (1 articles) Ji Hyun Kim
    16. (1 articles) Yoshinobu Onuma
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    Ultrathin side-viewing needle probe for optical coherence tomography 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method Focus defect and dispersion mismatch in full-field optical coherence microscopy Imaging outcomes of bioresorbable scaffold overlap: an optical coherence tomography analysis from the ABSORB EXTEND trial Combined spectral-domain optical coherence tomography and hyperspectral imaging applied for tissue analysis: preliminary results A Case Report of Occipital Lobe Epilepsy and Related Optical Coherence Tomography Findings Comparison of Central Corneal Thickness Measured by Swept-source Optical Coherence Tomography and Ultrasound Pachymetry One-year follow-up optical coherence tomography after endovascular treatment with a new-generation zotarolimus-eluting stent for chronic mesenteric ischemia Speckle noise reduction for optical coherence tomography images via non-local weighted group low-rank representation Stent loss during chronic total occlusion percutaneous coronary intervention: optical coherence tomography-guided stent ‘crushing and trapping Near-IR and CP-OCT imaging of suspected occlusal caries lesions