1. Articles from X. Yang

    1-3 of 3
    1. Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method

      Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method

      Fiber-optic probes for sensing and biomedical imaging applications such as optical coherence tomography (OCT) frequently employ sections of graded-index (GRIN) fiber to re-focus the diverging light from the delivery fiber. Such GRIN fiber microlenses often possess aberrations that cause significant distortions of the focused output beam. Current design methods based on ABCD matrix transformations of Gaussian beams cannot model such effects and are therefore inadequate for the analysis and design of high-performance probes that require diffraction-limited output beams. We demonstrate use of the beam propagation method (BPM) to analyze beam distortion in GRINlensed fibers resulting from index profiles that exhibit ...

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    2. 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe

      Evaluation of degradation in the structure of skeletal muscle is important for the assessment or diagnosis of many myopathies, such as Duchenne muscular dystrophy. Histological analysis is the gold standard to evaluate such degradation but requires excision and fixation of the tissue. This is undesirably invasive in patients and precludes longitudinal study of disease progression in patients or animal models. Optical coherence tomography (OCT) is a high-resolution (∼10μm) imaging modality capable of visualising muscle structure and the morphological changes in muscular dystrophy. However, because of the limited image penetration of OCT (∼2mm), previous studies have been restricted to imaging ...

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    3. Ultrathin side-viewing needle probe for optical coherence tomography

      Ultrathin side-viewing needle probe for optical coherence tomography

      We present the smallest reported side-viewing needle probe for optical coherence tomography (OCT). Design, fabrication, optical characterization, and initial application of a 30-gauge (outer diameter 0.31 mm) needle probe are demonstrated. Extreme miniaturization is achieved by using a simple all-fiber probe design incorporating an angle-polished and reflection-coated fiber-tip beam deflector. When inserted into biological tissue, aqueous interstitial fluids reduce the probe’s inherent astigmatism ratio to 1.8, resulting in a working distance of 300 μm and a depth-of-field of 550 μm with beam diameters below 30 μm. The needle probe was interfaced with an 840 nm spectral-domain OCT ...

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    1-3 of 3
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  2. Topics in the News

    1. (3 articles) University of Western Australia
    2. (3 articles) Dirk Lorenser
    3. (3 articles) David D. Sampson
    4. (2 articles) Xiaojie Yang
    5. (2 articles) Rodney W. Kirk
    6. (2 articles) Texas A&M University
    7. (2 articles) Oregon Health & Science University
    8. (2 articles) SUNY at Stony Brook
    9. (2 articles) Joseph A. Izatt
    10. (2 articles) Yingtian Pan
    11. (1 articles) Robert A. McLaughlin
    12. (1 articles) Duke University
    13. (1 articles) Baylor College of Medicine
    14. (1 articles) Brian E. Applegate
    15. (1 articles) Makoto Araie
    16. (1 articles) Javier A. Jo
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    Ultrathin side-viewing needle probe for optical coherence tomography 3D imaging of internal structures of skeletal muscle with an ultrathin side-viewing optical needle probe Accurate Modeling and Design of Graded-Index Fiber Probes for Optical Coherence Tomography using the Beam Propagation Method Software Postdoctoral Position in Optical imaging at Casey Eye Institute, Oregon Health & Science University Automated classification of optical coherence tomography images for the diagnosis of oral malignancy in the hamster cheek pouch Corneal Topographic Analysis of Patients With Mooren Ulcer Using 3-Dimensional Anterior Segment Optical Coherence Tomography A survey of current and anticipated use of standard and specialist equipment by UK optometrists Optical coherence Doppler tomography for quantitative cerebral blood flow imaging This is Your Brain's Blood Vessels on Cocaine Blood flow dynamics reflect degree of outflow tract banding in Hamburger-Hamilton stage 18 chicken embryos Evaluation of two quantitative analysis methods of optical coherence tomography for detection of enamel demineralization and comparison with microhardness - Cara - 2014 - Lasers in Surgery and Medicine - Wiley Online Library Relationship between Optical Coherence Tomography and Electrophysiology of the Visual Pathway in Non-Optic Neuritis Eyes of Multiple Sclerosis Patients